KEGG   Mus musculus (mouse): 23938Help
Entry
23938             CDS       T01002                                 

Gene name
Map2k5, AI324775, AI428457, MEK5, Mapkk5, Prkmk5
Definition
mitogen-activated protein kinase kinase 5 (EC:2.7.12.2)
Orthology
K04463  
mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
Organism
mmu  Mus musculus (mouse)
Pathway
MAPK signaling pathway
Gap junction
Neurotrophin signaling pathway
Oxytocin signaling pathway
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    23938 (Map2k5)
 Cellular Processes
  Cell communication
   04540 Gap junction
    23938 (Map2k5)
 Organismal Systems
  Endocrine system
   04921 Oxytocin signaling pathway
    23938 (Map2k5)
  Nervous system
   04722 Neurotrophin signaling pathway
    23938 (Map2k5)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     23938 (Map2k5)
Protein kinases [BR:mmu01001]
 Serine/threonine protein kinases: STE group
  STE7 family
   23938 (Map2k5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
MGI: 
Ensembl: 
UniProt: 
Structure
PDB: 

Jmol
Position
9 C; 9
AA seq 448 aa AA seqDB search
MLWLALGPFCAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAF
EYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGL
KVNTRAGPSQHTSPVVSDSLPSNSLKKSSAELRKILANGQMNEQDIRYRDTLGHGNGGTV
YKAHHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISIC
TEFMDGGSLDVYRKIPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTGGQVKLC
DFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQ
KNQGSLMPLQLLQCIVDEDSPVLPLGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIV
QFNDGNSTVVSMWVCRALEERRSQQGPP
NT seq 1347 nt NT seq  +upstreamnt  +downstreamnt
atgctgtggctggcccttggccccttctgtgccatggagaaccaggtgctggtgattcgg
atcaagattccaaatagtggcgcggtggactggaccgtgcactccgggccgcagttactc
ttcagggatgttctggatgtgataggccaggttctgcctgaagcgacgacgacagcgttt
gaatatgaagatgaagatggtgataggattacagtaagaagcgatgaagagatgaaggca
atgctgtcctactattattccacagtaatggaacagcaagtaaatggccagctaatagag
ccgctgcagatatttccaagagcctgcaagcctcctggggaacggaacatacatggcctg
aaggtgaatacacgggctgggccatctcaacacaccagccctgtggtctcagattcgctt
ccaagcaatagcttgaagaagtcctcagctgaactgagaaagatactggccaacggccag
atgaatgaacaagacatacggtatcgagacacccttggtcatggcaacggaggcacagtc
tacaaagcacatcatgtcccaagtgggaaaattttagctgtaaaggttattctgttagac
attacactggagcttcagaagcagatcatgtctgagctggaaatcctttataagtgtgac
tcatcgtatatcataggattttacggggcatttttcgtagaaaacaggatttcaatttgt
acagaattcatggatggggggtctttggatgtatataggaaaattccagagcacgtcctt
ggaagaattgcagttgcagttgttaaaggccttacctatctgtggagtttaaagatttta
cacagagatgtgaagccctccaacatgcttgtaaacacaggcggacaggtcaagctgtgt
gactttggcgtgagcacacagctggtgaattctatagccaagacgtatgttggaacaaat
gcttacatggcaccagaaagaatttcaggagagcagtatgggatccattctgacgtgtgg
agcttaggaatctctttcatggagcttgctcttgggaggtttccatatcctcagattcag
aaaaaccagggatctttaatgcctctccagcttctgcagtgcattgttgatgaggattcg
ccggtccttccgcttggagagttctcggagccgtttgtacatttcatcactcagtgcatg
aggaagcagcccaaggagagaccggcgcctgaggagctgatgggtcacccattcatcgtg
cagttcaatgatggaaactccactgtggtgtccatgtgggtgtgccgagctctagaggag
aggcggagccagcagggacccccgtga

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