KEGG   Mus musculus (mouse): 26397Help
Entry
26397             CDS       T01002                                 

Gene name
Map2k3, AW212142, MEK3, MKK3, Prkmk3, mMKK3b
Definition
mitogen-activated protein kinase kinase 3 (EC:2.7.12.2)
Orthology
K04432  
mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
mmu  Mus musculus (mouse)
Pathway
MAPK signaling pathway
Rap1 signaling pathway
Toll-like receptor signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
Inflammatory mediator regulation of TRP channels
GnRH signaling pathway
Amyotrophic lateral sclerosis (ALS)
Toxoplasmosis
Influenza A
Epstein-Barr virus infection
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    26397 (Map2k3)
   04010 MAPK signaling pathway
    26397 (Map2k3)
   04668 TNF signaling pathway
    26397 (Map2k3)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    26397 (Map2k3)
   04664 Fc epsilon RI signaling pathway
    26397 (Map2k3)
  Endocrine system
   04912 GnRH signaling pathway
    26397 (Map2k3)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    26397 (Map2k3)
 Human Diseases
  Neurodegenerative diseases
   05014 Amyotrophic lateral sclerosis (ALS)
    26397 (Map2k3)
  Infectious diseases
   05164 Influenza A
    26397 (Map2k3)
   05169 Epstein-Barr virus infection
    26397 (Map2k3)
   05145 Toxoplasmosis
    26397 (Map2k3)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     26397 (Map2k3)
Protein kinases [BR:mmu01001]
 Serine/threonine protein kinases: STE group
  STE7 family
   26397 (Map2k3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
MGI: 
Ensembl: 
Vega: 
UniProt: 
Position
11 B2; 11
AA seq 347 aa AA seqDB search
MESPAASPPASLPQTKGKSKRKKDLRISCVSKPPVSNPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNTQEQKRLLMDLDINMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLEKNMKIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADQFSPEFVD
FTSQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt NT seq  +upstreamnt  +downstreamnt
atggagtcgcccgccgcgagcccgccggccagcttgcctcagaccaaaggaaaatccaaa
aggaaaaaggacttacggatatcctgcgtgtccaagccacctgtgtccaaccccacaccc
ccccggaacctggactcccggaccttcatcactatcggagacagaaacttcgaagtggag
gctgatgacttggtgaccatctcagagctgggtcgtggagcctatggggtggtagagaaa
gtgcggcatgctcagagtggtaccatcatggctgtcaagcgcatccgggccacagtgaac
acacaggagcagaaacgtctgcttatggacctagacatcaacatgcgcacggtcgactgc
ttctacactgtcaccttctatggtgccctcttcagagagggggatgtatggatctgcatg
gagctcatggacacttccctggataagttctaccggaaggtgctggagaagaacatgaaa
attccggaagacatcctgggggagatcgctgtgtctatcgtgcgggccctggagcacctg
catagcaagctgtctgtgatccacagagatgtgaagccatccaatgtcctcatcaacaag
gaagggcatgtgaagatgtgcgactttggcatcagtggctacctggtggactctgtggca
aagacaatggatgctggctgcaagccttacatggcccctgagaggatcaaccctgaactg
aatcagaagggctacaatgtcaagtctgatgtctggagcctcggcatcaccatgatcgag
atggccattctgcgattcccttatgagtcttggggcacaccgttccagcagctgaagcag
gtggtggaggagccatccccacagctcccagcggaccagttctcccctgagtttgtggac
ttcactagccagtgcctaaggaagaaccctgcagagcgcatgagctacctggagctgatg
gaacacccattcttcaccttgcacaaaactaagaagacagacattgctgcctttgtgaag
gagatcctgggagaggattcatag

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