KEGG   Mus musculus (mouse): 26416Help
Entry
26416             CDS       T01002                                 

Gene name
Mapk14, CSBP2, Crk1, Csbp1, Mxi2, PRKM14, PRKM15, p38, p38-alpha, p38MAPK, p38a, p38alpha
Definition
mitogen-activated protein kinase 14 (EC:2.7.11.24)
Orthology
K04441  
p38 MAP kinase [EC:2.7.11.24]
Organism
mmu  Mus musculus (mouse)
Pathway
MAPK signaling pathway
Rap1 signaling pathway
FoxO signaling pathway
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Signaling pathways regulating pluripotency of stem cells
Platelet activation
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
RIG-I-like receptor signaling pathway
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Retrograde endocannabinoid signaling
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
GnRH signaling pathway
Progesterone-mediated oocyte maturation
Prolactin signaling pathway
Amyotrophic lateral sclerosis (ALS)
Salmonella infection
Pertussis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Hepatitis C
Influenza A
Epstein-Barr virus infection
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    26416 (Mapk14)
   04010 MAPK signaling pathway
    26416 (Mapk14)
   04370 VEGF signaling pathway
    26416 (Mapk14)
   04668 TNF signaling pathway
    26416 (Mapk14)
   04068 FoxO signaling pathway
    26416 (Mapk14)
 Cellular Processes
  Cellular commiunity
   04550 Signaling pathways regulating pluripotency of stem cells
    26416 (Mapk14)
 Organismal Systems
  Immune system
   04611 Platelet activation
    26416 (Mapk14)
   04620 Toll-like receptor signaling pathway
    26416 (Mapk14)
   04621 NOD-like receptor signaling pathway
    26416 (Mapk14)
   04622 RIG-I-like receptor signaling pathway
    26416 (Mapk14)
   04660 T cell receptor signaling pathway
    26416 (Mapk14)
   04664 Fc epsilon RI signaling pathway
    26416 (Mapk14)
   04670 Leukocyte transendothelial migration
    26416 (Mapk14)
  Endocrine system
   04912 GnRH signaling pathway
    26416 (Mapk14)
   04914 Progesterone-mediated oocyte maturation
    26416 (Mapk14)
   04917 Prolactin signaling pathway
    26416 (Mapk14)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    26416 (Mapk14)
  Nervous system
   04728 Dopaminergic synapse
    26416 (Mapk14)
   04723 Retrograde endocannabinoid signaling
    26416 (Mapk14)
   04722 Neurotrophin signaling pathway
    26416 (Mapk14)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    26416 (Mapk14)
  Development
   04380 Osteoclast differentiation
    26416 (Mapk14)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    26416 (Mapk14)
  Neurodegenerative diseases
   05014 Amyotrophic lateral sclerosis (ALS)
    26416 (Mapk14)
  Infectious diseases
   05132 Salmonella infection
    26416 (Mapk14)
   05133 Pertussis
    26416 (Mapk14)
   05152 Tuberculosis
    26416 (Mapk14)
   05164 Influenza A
    26416 (Mapk14)
   05160 Hepatitis C
    26416 (Mapk14)
   05169 Epstein-Barr virus infection
    26416 (Mapk14)
   05145 Toxoplasmosis
    26416 (Mapk14)
   05140 Leishmaniasis
    26416 (Mapk14)
   05142 Chagas disease (American trypanosomiasis)
    26416 (Mapk14)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     26416 (Mapk14)
Protein kinases [BR:mmu01001]
 Serine/threonine protein kinases: CMGC group
  MAPK family [OT]
   26416 (Mapk14)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
MGI: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
17 A3.3; 17 14.85 cM
AA seq 360 aa AA seqDB search
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG
TPPAYLINRMPSHEARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt NT seq  +upstreamnt  +downstreamnt
atgtcgcaggagaggcccacgttctaccggcaggagctgaacaagaccatctgggaggtg
cccgaacgataccagaacctgtccccggtgggctcgggcgcctatggctcggtgtgtgct
gcttttgatacaaagacggggcatcgtgtggcagttaagaagctgtcgagaccgtttcag
tccatcattcacgccaaaaggacctaccgagagttgcgtctgctgaagcacatgaaacac
gaaaatgtgattggtctgttggatgtgttcacacccgcaaggtcactggaggaattcaat
gacgtgtacctggtgacccatctcatgggggcggacctgaacaacatcgtgaagtgccag
aagctgaccgacgaccacgttcagtttctcatctaccagatcctccgagggctgaagtat
atacattcggctgacataattcacagggacctaaagcccagcaacctagctgtgaacgaa
gactgtgagctcaagattctggattttgggctggctcggcacactgatgatgagatgaca
ggctacgtggctaccaggtggtaccgagccccagagatcatgctgaattggatgcactat
aaccagacagtggatatttggtccgtgggctgcatcatggctgagctgttgaccggaaga
acgttgtttcctggtacagaccatattaaccagcttcagcagataatgcgtctgacgggg
acaccccctgcttatctcattaacaggatgccaagccatgaggcaagaaactacattcag
tctctggcccagatgccgaagatgaacttcgcaaatgtatttattggtgccaatcccctg
gctgtcgacctactggagaagatgctcgttttggactcagataagaggatcacagcagcc
caagctcttgcgcatgcctactttgctcagtaccacgaccctgatgatgagcctgttgct
gacccttatgaccagtcctttgaaagcagggaccttctcatagatgagtggaagagcctg
acctatgatgaagtcatcagctttgtgccaccaccccttgaccaagaagaaatggagtcc
tga

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