KEGG   Mus musculus (house mouse): 269878
Entry
269878            CDS       T01002                                 
Symbol
Megf8, Egfl4, b2b1702.2Clo, b2b1702Clo, b2b288Clo, m687Ddg, mKIAA0817
Name
(RefSeq) multiple EGF-like-domains 8
  KO
K23664  multipile epidermal growth factor-like domains protein 8
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04340  Hedgehog signaling pathway
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    269878 (Megf8)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified [BR:mmu04990]
    269878 (Megf8)
Domain-containing proteins not elsewhere classified [BR:mmu04990]
 Laminin domain-containing proteins
  Laminin EGF-like domain-containing proteins
   269878 (Megf8)
SSDB
Motif
Pfam: Kelch_3 Kelch_4 Kelch_5 Kelch_1 Kelch_6 CUB Laminin_EGF EGF_CA EGF_3 PSI EGF_2 PSI_integrin hEGF EGF
Other DBs
NCBI-GeneID: 269878
NCBI-ProteinID: NP_001153872
MGI: 2446294
Ensembl: ENSMUSG00000045039
UniProt: P60882
Position
7:25016589..25065342
AA seq 2789 aa
MALGGALALALALALAVLGPLSLRVLAGDCKGQRQVLREAPGFVTDGAGNYSVNGNCEWL
IEAPSPQHRILLDFLFLDTECTYDYLFVYDGDSPQGPLLASLSGSTRPPPIEASSGKMLL
HLFSDANYNLLGFNASFRFSLCPGGCQNHGQCKSPGVCVCEPGWGGPDCGLQECSAYCGS
HGTCASTLGPCRCEPGFLGRACDLHLWENQGAGWWHSVSAGDPAFSARIGAAGAFLSPPG
LLAVFGGQDLNKALGDLVLYNFSTNTWESWDLTPAPAARHSHVAVAWAGLLVLMGGELAN
GLLTNDVWAFSPLGGGHWELLAPPASSSSGPPGLAGHAAALVDDIWLYVSGGRTQHDLFS
SGLFRFRLDHTSRGYWEQVIPAGGRPPAATGHSMVFHAPSRTLLVHGGHRPSTARFSVRV
NSTELFHVERRVWTTLKGRDGLQGPRERAFHTASVLGNYMVVYGGNVHTHYQEEKCYEDG
IFFYHLGCHQWVSGAELAPPGTPEGRAAPPSGRYSHVAAVLGGSVLLVAGGYSGRPRGDL
MAYKVPPFVFQAPALDYHLDYCSMYTDHSVCSRDPECSWCQGACQAAPPPGTPSGACPAA
SCLGLGRLLSDCQACLAFSSPTAPPRGPGALGWCVHNESCLPRPEQARCRGEQISGTVGW
WGPAPVFVTSLEACVTQSFLPGLHLLTFQQPPNASQPDKVSIVRSTTITLTPSPETDVSL
VYRGFIHPLLPGGPGGPGAEDVAVWARAQRLHVLARMARGPDTENMEEVGRWVAQQEKET
RRLQRPGSDRLFPLPGRGNKYAVEIRGQLNGSAGPGHSELTLLWDRTGVPGGSEISFFFL
EPYRSSACTSYSSCLGCLADQGCGWCLNSATCHLRQGRAHCEDDGSGESLLVLVPALCPL
CEEHRDCHACTQDPFCEWHQSTNRKGDAACSRRGRGRGALKNPEECPPLCSQRLTCEDCL
ANSSQCAWCQSTHTCFLFAAYLARYPHGGCRGWDDSVHSEPRCRSCGGFLTCHECLQSHE
CGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLPVALPARWAYARCPDVDECRL
GLARCHPRATCLNTPLSYECHCQRGYQGDGITHCNRTCLEDCGHGVCSGPPDFTCVCDLG
WTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRRRGPGYCDECQDWTWGEHCERCRPGSFG
NATGSGGCRPCQCNGHGDPRRGHCDNLTGLCFCQDHTEGAHCQICSPGYYGDPRAGGSCF
RECGGRALLTNVSSVALGSRRFGGLLPPGGGAARAGPGLSYCVWVVSATEALQPCVPGTL
CPPLTLTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQAL
SGLLVLHWEANGSSSWGFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWA
GPHCRMALCPENCNAHTGAGICNQSLGVCICAEGFGGPDCATKLDGGQLVWETLMDSRLS
ADTASRFLHRLGHTMVEGPDATLWMFGGLGLPQGLLGNLYRYSVSERRWTQMLAGAEDGG
PGPSPRSFHAAAYVPAGRGAMYLLGGLTAGGVTRDFWVLNLTTLQWRQEKPPQNMELPAV
AGHTLTARRGLSLLLVGGYSPENGFNQQLLEYQLATGTWVSGAQSGTPPTGLYGHSAVYH
EATDSLYVFGGFRFHVELAAPSPELYSLHCPDRTWSLLAPSQGAKPRPRLFHASALLGDT
MVVLGGRSDPDEFSSDVLLYQVNCNTWLLPALTRPAFVGSPMEESVAHAVAAVGSRLYIS
GGFGGVALGRLLALTLPPDPCRLLPSPEACNQSGACTWCHGACLSGDQAHRLGCGVPPCS
PMPRSPEECRRLRTCSECLARHPRTLQPGDGEASIPRCKWCTNCPEGACIGRNGSCTSEN
DCRINQREVFWAGNCSEAACGAADCEQCTREGKCMWTRQFKRTGETRRILSVQPTYDWTC
FSHSLLNVSPMPVESSPPLPCPTPCHLLPNCTSCLASKGADGGWQHCVWSSSLQQCLSPS
YLPLRCMAGGCGRLLRGPESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGHCMEGGLS
GPRDGLTCGRPGASWAFLSCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNVT
GVCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSECAGVGAQDHCLLCRNH
TKGSHCEQCLPLFVGSALGGGTCRPCHAFCRGNSHVCVSRKELEMARKEPEKYSLDPEEI
ETWVAEGPSEDEAVCVNCQNNSYGDRCESCLHGYFLLDGKCTKCQCNGHADTCNEQDGTG
CPCQNNTETGTCQGSSPSDRRDCYKYQCAKCRESFHGSPLGGQQCYRLISVEQECCLDPT
SQTNCFHEPKRRALGPGRTVLFGVQPKFTNVDIRLTLDVTFGAVDLYVSTSYDTFVVRVA
PDTGVHTVHIQPPPPPPPPPPPADGVPRVAADLGGLGTGSGSGSPVEPRVREVWPRGLIT
YVTVTEPSAVLVVRSVRDRLVITYPHEHHALKSSRFYLLLLGVGDPNGPGANGSADSQGL
LFFRQDQAHIDLFVFFSVFFSCFFLFLSLCVLLWKAKQALDQRQEQRRHLQEMTKMASRP
FAKVTVCFPPDPAGPAPAWKPAGLPPPAFRRSEPFLAPLLLTGAGGPWGPMGGGCCPPAL
PATTAGLRAGPITLEPTEDGMAGVATLLLQLPGGPHAPNGACLGSALVTLRHRLHEYCGG
SGGAGGSGHGGGGGRKGLLSQDNLTSMSL
NT seq 8370 nt   +upstreamnt  +downstreamnt
atggccttgggtggagctctggccttggcccttgcactggccttggcagtgctgggaccg
ctgtccctcagggtcctggctggtgactgcaaggggcagcggcaggtgctacgggaggcg
ccaggcttcgtgacggatggtgcgggcaactacagcgtcaacggcaactgcgagtggctt
atcgaggccccgagccctcagcaccggatcctgctggacttccttttcctggacacggag
tgcacttatgactacctctttgtgtatgacggtgactcgccccaaggccctctgcttgct
agtctgagtgggagcacccggcccccacccattgaggcttcctcaggcaagatgctcctc
cacctcttcagcgatgccaactacaacctgctgggctttaacgcctccttccgcttctcc
ctgtgtcccggaggctgccagaaccatgggcagtgcaagtccccgggagtgtgcgtttgc
gagccgggctggggaggtccagactgcggcctgcaggagtgctcagcctactgtggcagc
catggcacctgcgcctcgaccctgggaccatgccgctgtgaacctggattcttgggacga
gcctgtgacctgcacttgtgggagaaccagggggctggttggtggcacagtgtgagtgcc
ggggaccctgccttctctgcccgaattggggcagctggtgcctttctgtccccaccaggg
ctgctggctgtctttggaggccaggaccttaacaaggccctgggtgaccttgtcctgtat
aacttctccacgaacacctgggagtcctgggacctgacgcctgctccggctgcccgtcat
tctcatgtggccgtggcctgggctggcttgctggtgctgatgggtggtgagctggccaat
ggcttgctaaccaatgatgtgtgggcctttagccccctgggtggaggccactgggagctc
ctggcaccacctgcttccagttcttctgggcccccggggctggcaggccatgcagctgct
ctggtggatgacatctggctttatgtgtccggtggccgcactcagcatgacctcttttct
tctggcctcttccggttccgcctggaccacaccagcaggggctattgggagcaggtgatc
ccggcaggtgggcggccccctgctgccactgggcactctatggtgttccatgccccatct
cgtactctgctggtccatggtggacaccggccttccactgcccggttttctgtgcgggtg
aattccactgagctcttccacgtggaacggcgtgtgtggaccacgctgaagggccgggat
gggctccagggtccacgggagagagccttccacactgccagtgttctaggaaactacatg
gtggtctatgggggcaatgtgcatacgcattaccaggaggaaaagtgttacgaagatggc
atcttcttctaccaccttggctgccaccagtgggtgtcaggggctgagcttgccccgcca
ggaacccctgagggtcgagcggcgcctcctagtggccgttactcacatgtggcagctgtt
cttggtggcagtgtcctgctggtggctgggggatatagtggccggcctcgtggggacttg
atggcctacaaggtgccccccttcgtgtttcaggcacctgccctagattaccacctggac
tattgttccatgtacacagaccacagtgtctgctcccgagacccggaatgcagctggtgt
cagggcgcttgccaagctgcgccccctcctgggactccctcaggagcttgtccagcggcc
agctgcctgggcctaggccgcctgctaagtgactgccaagcatgcctggccttcagcagc
cccacagctcctccccggggacctggcgccctaggttggtgtgtgcacaatgagagctgc
cttcctcggcctgagcaggcccgctgccgaggggagcagatctcaggcaccgtgggctgg
tgggggccagcacccgtcttcgtcacttccctggaggcttgtgtcacccagagcttcctc
cctggcctgcacctgctcaccttccagcagccacccaacgcctctcagcctgacaaggtc
tccattgtccgaagtacaactatcaccttgacacccagcccggagacagatgtgtcccta
gtctaccgaggcttcatccaccccctgctgccaggaggaccaggcggccctggggctgaa
gatgtggctgtgtgggctcgggcccagcgtctccatgtcctggcccggatggccagaggc
cctgacactgagaacatggaggaggtgggacgctgggtggctcagcaggagaaggagaca
cggcgtctgcagcgccctggctctgatcgcctcttcccattgccggggagaggcaacaag
tacgcggtggagatccgaggccagctcaacggctcggcaggccctgggcatagtgagctc
accctcctgtgggatcggactggagtgccgggtggcagtgagatctccttcttcttcctg
gagccctaccgctcttcggcctgcacctcctactcctcctgtctgggctgcctggctgat
cagggctgtggctggtgcctcaacagtgccacctgtcacctgcgtcaaggcagggcccac
tgtgaggatgatgggagcggcgagtccctgctggtgctggtgcctgccctctgtccactc
tgtgaggagcatcgtgactgtcatgcctgcacccaggaccccttctgtgagtggcatcag
agcaccaaccgcaaaggagatgcagcgtgcagccggcgaggccggggccgaggcgctctg
aagaacccagaggaatgccccccactctgcagccaacggctgacctgtgaggactgcctg
gccaactccagccagtgtgcctggtgccagtctactcacacctgcttcctgtttgctgcc
tacctggcccggtacccacatgggggctgccgtggctgggatgacagtgtgcactcagag
ccacggtgcaggagctgcggtggctttttgacttgtcatgagtgtctgcagagccacgag
tgtggttggtgtggcaacgaagacaaccccactctgggacggtgcctacaaggggacttc
tctggacccctgggtggggggaactgctccctctgggtgggagagggcctgggcctgcct
gtggctctccctgcccgctgggcttatgcccgctgtccagatgtggatgaatgtcgcctg
ggcctggcgaggtgtcacccacgggcaacctgcctgaacacgcctctcagctatgagtgt
cattgccagcgtggctaccagggcgatggcatcacacactgtaaccgcacgtgcctggaa
gactgtggccacggtgtgtgtagcggtcctccggacttcacttgtgtgtgtgacctgggc
tggacctcagacctgcccccacccacgcctgccccaggaccccctgcccctcgttgctct
cgggactgtggctgcagctttcatagccactgccgcaggcggggacctggctactgtgac
gagtgccaggactggacgtggggggaacactgtgaacggtgccggcctggcagctttggc
aatgcaaccggctctggtggctgccgaccctgccagtgtaacgggcatggggacccacgt
cgtggccactgtgacaacctcactgggctctgcttctgccaggaccacactgagggtgcc
cactgtcagatttgctctccaggatactatggggacccccgagctggtggctcctgcttc
cgggagtgtgggggtcgtgcgctcctcaccaatgtgtcctcggtggctctgggctcccgc
cgctttgggggacttctgcctccaggtggtggggcagcaagagctgggcccgggctgtcc
tactgcgtgtgggttgtctctgccacagaagcgctgcagccctgtgtccctggcaccctc
tgccccccgctcaccctcaccttctctccagacagcagcacgccttgcacactgagctac
gtcctggcctttgatggattcccacgcttcctggacactggtgttgttcagtcagaccgg
agcctcatagctgccttctgcggccagcggcgtgacagacctctcactgtgcaggcttta
tcagggttacttgtgttgcactgggaagccaacggctcctcctcctggggattcaatgct
tctgtgggctctgcccggtgtggatcaggaggtcctggcagttgccctgtccctcaggaa
tgtgtgccccaggatggggctgcaggtgctggcctctgccgctgtcctcagggctgggct
ggccctcactgccgcatggctctgtgtcctgagaattgcaacgcccacaccggggcaggg
atttgtaaccagagcctaggtgtgtgcatctgtgctgagggctttggcggcccagactgt
gccacgaagctggatggtggacagttggtctgggaaacgctcatggacagccgcctctca
gctgatactgctagtcgcttccttcaccgcctgggacatactatggtagaggggcctgat
gccactttgtggatgtttgggggcctgggtctgccacagggcctgctgggaaacctgtac
aggtattcagtcagtgagcgcagatggacacagatgttggcaggagctgaggatgggggc
ccaggcccatcaccccgttccttccatgcagccgcctatgtgcctgctggccgaggtgcc
atgtacctgctggggggcctcacagctggaggcgtcacccgtgacttctgggtccttaac
ctcactaccctgcagtggagacaggagaagccccctcagaacatggagttgccagcggtc
gctggtcacacccttactgcccgtcgaggcctatctctgctcttggtgggtggctactcc
cccgaaaatggcttcaaccagcagttgttggagtaccagctagcaaccggcacctgggta
tctggagcccagagtgggacacccccaacaggtctctatggtcattctgcagtctaccac
gaggccaccgactccctctatgtgtttgggggtttccgcttccacgtggagctggcagca
ccttctccggagctctactccctgcactgtcctgaccgtacctggagcctgctggcacct
tctcagggggcaaagccccgaccccggcttttccacgcttcagctctgctcggagacacc
atggtggtccttggggggcgctcggaccctgatgaattcagcagtgatgttctgctctac
caggtcaactgcaacacctggctcctgcctgccctcacccgtccagcctttgtggggtcc
ccgatggaggagtctgtggcccatgcagtggcagcagttggtagccgcctgtacatctct
ggaggatttgggggagtagccttgggccgcctgctggcattgaccttgccccccgacccc
tgccgtctgctgccttcacctgaagcttgtaatcagtctggggcctgcacctggtgccat
ggtgcttgcctgtctggggaccaggcccacaggctgggttgtggggtgcccccttgctcc
ccaatgcctcgctcgcctgaggaatgtcggaggctgcggacctgcagtgagtgcctggcc
cgccatcctcggaccctgcagcctggagatggagaggcatccattccccgttgtaagtgg
tgtaccaactgcccagagggtgcctgcattgggcgcaatgggtcctgcacctcagagaat
gactgccgaatcaaccagcgagaggtcttctgggctggcaactgctcagaggctgcgtgt
ggggctgctgactgtgagcagtgcacgcgggagggcaagtgcatgtggacgcggcagttc
aagaggaccggggagactcgccgaatcctgtcagtgcagcccacctatgactggacttgc
ttcagccattccctgttgaatgtgtctcctatgccagtggagtcctcgcctccactgccc
tgccccacgccctgtcacctcctgcccaactgcacatcgtgcctggcctccaagggtgca
gatgggggctggcagcactgtgtgtggagcagcagcctccagcagtgtctgagcccctcc
tatctgcccttgcgatgtatggctggaggctgtgggcggctgcttagagggccagagagc
tgctcgctgggctgtgctcaggcgacacagtgtgccctgtgcctgcgacgaccccactgt
ggctggtgtgcctggggaggccaggatgggggtggccattgcatggaaggaggtctcagt
ggtccccgagacgggctaacgtgtggacgtcccggggcctcctgggccttcctgtcttgc
ccccctgaggacgagtgtgcaaatgggcaccatgactgcaatgagacccagaactgccat
gaccagccccacggctacgagtgcagctgcaagacaggctacaccatggacaatgtgact
ggcgtctgccgccctgtgtgcgcccagggctgtgtgaacggatcctgtgtggagcctgat
cactgccgctgtcactttggctttgttggccgcaactgctccacagagtgtcgctgcaac
cgccacagtgagtgtgccggcgttggagcacaggaccactgcctgctgtgccggaaccac
accaagggtagccactgtgagcagtgtctcccactgttcgtgggttcggctttgggcggt
gggacctgccgaccctgccatgccttctgtcgcgggaacagccatgtgtgcgtctccagg
aaagagctagaaatggccagaaaggagccagagaagtactcactggatccagaggagatt
gaaacctgggtggcagaaggtcccagtgaagatgaagctgtgtgtgtgaactgtcagaac
aacagctacggggacagatgtgagagctgcctccacggctactttctcctggacgggaaa
tgcaccaagtgccagtgtaatggccacgctgacacctgtaacgagcaggacgggacagga
tgcccatgtcagaacaacacagagacaggcacctgccagggcagctctcccagtgaccgc
cgagactgctacaagtaccagtgtgctaagtgccgcgagtcattccacgggagcccgcta
ggtggccagcagtgttaccgactcatctctgtggaacaagagtgctgcctggaccccact
tcccagaccaactgcttccatgagccaaagcgccgggccctgggtcctggccgcaccgtg
ctgtttggcgtccaacccaagttcaccaatgtggacattcgcctgacactagacgtgacc
ttcggcgctgtggacctctatgtctccacctcctatgacacttttgtggtccgagtggcc
cctgacacaggcgtccacactgtgcacatccagccacctccacctcccccacctcccccg
cctcctgctgatggtgtacctcgggtggctgcggacctaggaggattggggactggaagt
gggtcaggatctccggtggagccacgggtccgggaggtgtggccacggggcctgattacc
tacgtcacagtgacggaaccctcggcagtgctggtggtccgcagtgtgagggacaggctg
gtgatcacctatccccatgagcaccacgccctcaaatccagccgcttctacctgctgctg
ctgggtgtaggagaccccaacgggcctggtgccaacggttcagcagactcacagggcctg
ctcttcttccggcaagaccaggcccacattgacctgttcgtcttcttctctgtcttcttt
tcctgcttcttcctcttcctctcactctgtgtgctcctctggaaggccaagcaggctctg
gaccagcgacaagagcagcgccgccacctgcaggagatgaccaagatggccagccgcccc
tttgccaaggtcactgtctgcttccctccagaccctgcaggcccagcacctgcatggaag
ccagctgggctccctcctcctgccttccgccgctctgagcctttcctagcacccctgttg
ctgacaggagccgggggtccctggggacccatgggaggcgggtgctgcccaccagccctc
cctgccaccacagctggcctacgagctggacccatcacccttgagcccacagaagatggc
atggctggtgtggccactctgctgctccagctgcctgggggtcctcatgctcccaatggg
gcctgccttgggtcagccctcgtcactctgcgtcataggctccatgagtactgtgggggc
agcgggggtgctggaggcagtggacacgggggtggtggaggccggaagggactgttgagt
caggacaatctcactagcatgtccctttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (133)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (127)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (15)   
   RefSeq(nuc) (1)   
   GenBank (7)   
   EMBL (7)   
Protein domain (14)   
   Pfam (14)   
All databases (169)   

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