KEGG   Mus musculus (mouse): 29857Help
Entry
29857             CDS       T01002                                 

Gene name
Mapk12, AW123708, Erk6, P38gamma, Prkm12, Sapk3
Definition
mitogen-activated protein kinase 12 (EC:2.7.11.24)
Orthology
K04441  
p38 MAP kinase [EC:2.7.11.24]
Organism
mmu  Mus musculus (mouse)
Pathway
MAPK signaling pathway
Rap1 signaling pathway
FoxO signaling pathway
Oocyte meiosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Signaling pathways regulating pluripotency of stem cells
Platelet activation
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
RIG-I-like receptor signaling pathway
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Retrograde endocannabinoid signaling
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
GnRH signaling pathway
Progesterone-mediated oocyte maturation
Prolactin signaling pathway
Amyotrophic lateral sclerosis (ALS)
Salmonella infection
Pertussis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Hepatitis C
Influenza A
Epstein-Barr virus infection
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    29857 (Mapk12)
   04010 MAPK signaling pathway
    29857 (Mapk12)
   04370 VEGF signaling pathway
    29857 (Mapk12)
   04668 TNF signaling pathway
    29857 (Mapk12)
   04068 FoxO signaling pathway
    29857 (Mapk12)
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    29857 (Mapk12)
  Cellular commiunity
   04550 Signaling pathways regulating pluripotency of stem cells
    29857 (Mapk12)
 Organismal Systems
  Immune system
   04611 Platelet activation
    29857 (Mapk12)
   04620 Toll-like receptor signaling pathway
    29857 (Mapk12)
   04621 NOD-like receptor signaling pathway
    29857 (Mapk12)
   04622 RIG-I-like receptor signaling pathway
    29857 (Mapk12)
   04660 T cell receptor signaling pathway
    29857 (Mapk12)
   04664 Fc epsilon RI signaling pathway
    29857 (Mapk12)
   04670 Leukocyte transendothelial migration
    29857 (Mapk12)
  Endocrine system
   04912 GnRH signaling pathway
    29857 (Mapk12)
   04914 Progesterone-mediated oocyte maturation
    29857 (Mapk12)
   04917 Prolactin signaling pathway
    29857 (Mapk12)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    29857 (Mapk12)
  Nervous system
   04728 Dopaminergic synapse
    29857 (Mapk12)
   04723 Retrograde endocannabinoid signaling
    29857 (Mapk12)
   04722 Neurotrophin signaling pathway
    29857 (Mapk12)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    29857 (Mapk12)
  Development
   04380 Osteoclast differentiation
    29857 (Mapk12)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    29857 (Mapk12)
  Neurodegenerative diseases
   05014 Amyotrophic lateral sclerosis (ALS)
    29857 (Mapk12)
  Infectious diseases
   05132 Salmonella infection
    29857 (Mapk12)
   05133 Pertussis
    29857 (Mapk12)
   05152 Tuberculosis
    29857 (Mapk12)
   05164 Influenza A
    29857 (Mapk12)
   05160 Hepatitis C
    29857 (Mapk12)
   05169 Epstein-Barr virus infection
    29857 (Mapk12)
   05145 Toxoplasmosis
    29857 (Mapk12)
   05140 Leishmaniasis
    29857 (Mapk12)
   05142 Chagas disease (American trypanosomiasis)
    29857 (Mapk12)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     29857 (Mapk12)
Protein kinases [BR:mmu01001]
 Serine/threonine protein kinases: CMGC group
  MAPK family [OT]
   29857 (Mapk12)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
MGI: 
Ensembl: 
UniProt: 
Position
15 E3; 15
AA seq 367 aa AA seqDB search
MSSPPPARKGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDESLDDFTDFYLVMPFMGTDLGKLM
KHETLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKILFKGNDHLDQLKEIMK
ITGTPPPEFVQKLQSAEAKNYMEGLPELEKKDFASVLTNASPQAVNLLERMLVLDAEQRV
TAAEALTHPYFESLRDTEDEPKAQKYDDSFDDVDRTLEEWKRVTYKEVLSFKPPRQLGAR
VPKETAL
NT seq 1104 nt NT seq  +upstreamnt  +downstreamnt
atgagctccccgccacccgcccgcaagggcttttaccgccaggaggtgaccaaaacggcc
tgggaggtgcgcgccgtgtaccaagacctgcagcccgttggctctggtgcctatggtgca
gtgtgctctgcagtagacagccgcactggcaacaaggtggccatcaagaagttgtaccgg
cccttccagtcggagctgtttgccaagcgcgcctacagagagttgcgcctcctcaaacac
atgcgccacgagaacgtcattgggctactggatgtgttcacacctgatgagtctctggac
gacttcacagacttctacctggtgatgccattcatgggcactgatctgggcaaactcatg
aagcatgagaccctgagtgaagacagaatccagtttcttgtgtatcagatgttgaagggg
ctgaagtatatccatgcggctggtgtcatccacagagacttgaagcctggcaacctggct
gtgaatgaggactgtgagctgaagatcctagactttggccttgccaggcaggcagacagt
gagatgacaggatatgtggtaacccggtggtatcgggcaccagaggtcatcttgaattgg
atgcgctacacgcagacagtggacatttggtccgttggctgcatcatggcggagatgatt
actgggaagatcctgttcaaaggcaatgaccacctggaccagctgaaggagatcatgaag
atcacagggacgccccctcctgagtttgttcagaagctacagagtgcagaggccaagaac
tacatggaaggcctccctgagttagaaaagaaggattttgcctctgtcctgaccaacgca
agccctcaggctgtgaatctcctggaaaggatgctggtgctggatgcggaacagcgggtg
acagcagctgaggcgttaacccatccatactttgagtcccttcgggacactgaggatgaa
cccaaggcccagaaatatgacgactcctttgatgatgtagaccgcacccttgaggaatgg
aagcgtgtgacttacaaggaagttctcagcttcaagcctcctaggcagctaggagccaga
gttccaaaggagacggctctgtga

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