KEGG   Mus musculus (mouse): 30955Help
Entry
30955             CDS       T01002                                 

Gene name
Pik3cg, 5830428L06Rik, PI3Kgamma, p110gamma
Definition
(RefSeq) phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
  KO
K21289  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu00562  Inositol phosphate metabolism
mmu04022  cGMP-PKG signaling pathway
mmu04072  Phospholipase D signaling pathway
mmu04151  PI3K-Akt signaling pathway
mmu04261  Adrenergic signaling in cardiomyocytes
mmu04371  Apelin signaling pathway
mmu04611  Platelet activation
mmu04725  Cholinergic synapse
mmu04921  Oxytocin signaling pathway
mmu05145  Toxoplasmosis
mmu05167  Kaposi's sarcoma-associated herpesvirus infection
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    30955 (Pik3cg)
 Environmental Information Processing
  Signal transduction
   04371 Apelin signaling pathway
    30955 (Pik3cg)
   04072 Phospholipase D signaling pathway
    30955 (Pik3cg)
   04022 cGMP - PKG signaling pathway
    30955 (Pik3cg)
   04151 PI3K-Akt signaling pathway
    30955 (Pik3cg)
 Organismal Systems
  Immune system
   04611 Platelet activation
    30955 (Pik3cg)
  Endocrine system
   04921 Oxytocin signaling pathway
    30955 (Pik3cg)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    30955 (Pik3cg)
  Nervous system
   04725 Cholinergic synapse
    30955 (Pik3cg)
 Human Diseases
  Infectious diseases
   05167 Kaposi's sarcoma-associated herpesvirus infection
    30955 (Pik3cg)
   05145 Toxoplasmosis
    30955 (Pik3cg)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     30955 (Pik3cg)
Membrane trafficking [BR:mmu04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    30955 (Pik3cg)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PI3Ka PI3_PI4_kinase PI3K_rbd PI3K_C2 DUF4135 DUF3244
Motif
Other DBs
NCBI-GeneID: 30955
NCBI-ProteinID: NP_001139672
MGI: 1353576
Ensembl: ENSMUSG00000020573
Vega: OTTMUSG00000033083
UniProt: Q9JHG7 Q3UVA4 Q8C5Q7
Position
12; 12 A3
AA seq 1102 aa AA seqDB search
MELENYEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFVLPTSQRISKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDQFLLLYQKKGQWYEIYDRYQVVQTLD
CLHYWKLMHKSPGQIHVVQRHVPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKIANNCIFIVIHRGTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMNISESQSEQDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNG
DEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFAEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCCKTPSLSSKASAETPGSESKGKAQLLYYVNLLLIDHRFLLRHGDY
VLHMWQISGKAEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREIWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLQDFTQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLESLQNSNLP
ESFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFKCADPTVLSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAQIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGSSGKKTSPHFQKFQDVCVRAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
NT seq 3309 nt NT seq  +upstreamnt  +downstreamnt
atggagctggagaactatgaacaaccggtggttctaagagaggacaacctccgccggcgc
cggaggatgaagccacgcagcgcagcaggcagcctgtcttccatggagctcatccccatt
gagttcgtactgcccaccagccagcgcatcagcaagactccagaaacagcgctgctgcat
gtggctggccatggcaatgtggaacagatgaaagctcaggtgtggctgcgcgcactggag
accagtgtggctgcggagttctaccaccgattgggcccggaccaattcctcctgctctac
cagaagaaaggacaatggtatgagatctatgacaggtaccaagtggtgcagaccctagac
tgcctgcattactggaagttgatgcacaagagccctggccagatccacgtggtacagcga
cacgtaccttctgaggagaccttggctttccagaagcagctcacctccctgattggctat
gacgtcactgacatcagcaatgtgcacgatgatgagctagagttcactcgccgccgtctg
gttacgccccgcatggctgaagtggctggccgggatgccaaactctatgctatgcaccct
tgggtaacgtccaaacctctcccagactacctgtcaaaaaagattgccaacaactgcatc
ttcatcgtcatccaccgcggtaccaccagccaaaccatcaaggtctccgcagatgatact
cctggtaccatcctccagagcttcttcaccaagatggccaagaagaagtccctaatgaat
atctcagaaagtcaaagtgagcaggattttgtattgcgggtttgtggccgcgatgagtac
ctggtgggtgaaacacccctcaaaaatttccagtgggtgaggcagtgcctcaagaacgga
gatgaaatacacctggtgctcgacacgcctccagacccagcccttgatgaggtgaggaag
gaagaatggccgctggtggatgactgcactggagtcaccggctaccacgagcagctgacc
atccatggcaaggaccacgagagtgtgttcacagtgtctttgtgggactgcgaccgaaag
ttcagggtcaagatcagaggcattgatatccctgtcctgcctcggaacaccgacctcact
gtgtttgtggaagcgaacatccagcacgggcaacaagtcctctgccaaaggagaaccagc
cctaagcccttcgcagaagaggtactctggaatgtgtggctggagtttggcatcaaaatc
aaagacttgcccaaaggggctctattgaacctacagatctactgctgcaaaaccccatca
ctgtccagcaaggcttctgcagagactccaggctccgagtccaagggcaaagcccagctt
ctctattacgtgaacttgctgttaatagaccaccgtttcctcctccgccacggggactat
gtgctccacatgtggcagatatctggcaaggcagaggagcagggcagcttcaatgctgac
aagctcacatccgcaaccaatcctgacaaggagaactcaatgtccatttccatcctgctg
gacaattactgtcaccccatagctttgcctaagcaccggcccacccctgacccagaggga
gacagggttcgggctgaaatgcccaatcagcttcgaaagcaattggaggcgatcatagcc
acagatccacttaaccccctcacagcagaggacaaagaattgctctggcattttcgatat
gaaagcctgaagcatccgaaggcttaccctaagctattcagctcagtgaaatgggggcag
caagaaattgttgccaaaacgtaccagctgttagccagaagggagatctgggatcaaagt
gctttggacgttggcttaaccatgcagctcctggactgcaacttttcagacgagaatgtc
cgggccattgcagttcagaaactggagagcttagaggacgatgacgttttacattacctt
ctccagctggtacaggctgtgaaatttgaaccgtaccacgacagtgcgctggccagattc
ctgctgaagcgtggcttgaggaacaaaagaatcggtcacttcttgttctggttcctgcga
agtgagatcgcacagtccagacactatcagcagaggttcgctgtgatcctggaggcgtac
ctgcgaggctgtggcacagccatgttgcaggacttcacacagcaggtccatgtgattgag
atgttacagaaagtcaccattgatattaaatcgctctcggcagagaagtatgacgtcagt
tcccaagttatttcacagcttaagcaaaagcttgaaagccttcagaactccaatctcccc
gagagctttagagttccctatgatcctggactaaaagccggtaccctggtgatcgagaaa
tgcaaagtgatggcctccaagaagaagcccctgtggcttgagtttaagtgtgctgatccc
acagtcctatccaacgaaaccattggaatcatctttaaacatggtgatgatctgcgccaa
gacatgttgatcttgcagattctacgcatcatggagtccatttgggagactgaatctctg
gacctgtgccttctgccttacggttgcatctcaactggtgacaaaataggaatgatcgag
attgtaaaggatgccacaacgatcgctcaaattcagcaaagcacagtgggtaacacgggg
gcattcaaagatgaagtcctgaatcactggctcaaggaaaaatgtcctattgaagaaaag
tttcaggccgcagtggaaaggtttgtttactcctgtgcaggctactgtgtggccacattt
gttcttgggatcggtgacaggcacaacgacaacattatgatctcagagacaggaaaccta
tttcatatagacttcggacacattcttgggaattacaagagtttcctgggcatcaataaa
gagagagtgcccttcgtcctaaccccagacttcttgtttgtgatgggatcttctggaaaa
aagacaagtccacacttccagaaattccaggatgtctgtgttagagcttacctagctctt
cgccatcacacaaacctgttgatcatcttgttctccatgatgctgatgacaggaatgccc
cagctgacaagcaaagaggacattgaatatatccgggatgccctcaccgtgggaaaaagc
gaggaggacgctaagaaatatttccttgatcagatcgaagtctgcagagacaaaggatgg
actgtgcagtttaactggttcctacatcttgttcttggcatcaaacaaggagaaaagcac
tccgcttga

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