KEGG   Mus musculus (mouse): 394436Help
Entry
394436            CDS       T01002                                 

Gene name
Ugt1a1, Gnt1, UDPGT_1-1, UGT1A01, Udpgt-1a, UgtBr1
Definition
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)
Orthology
K00699  
glucuronosyltransferase [EC:2.4.1.17]
Organism
mmu  Mus musculus (mouse)
Pathway
Pentose and glucuronate interconversions
Ascorbate and aldarate metabolism
Steroid hormone biosynthesis
Starch and sucrose metabolism
Retinol metabolism
Porphyrin and chlorophyll metabolism
Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Drug metabolism - other enzymes
Metabolic pathways
Chemical carcinogenesis
Module
Glucuronate pathway (uronate pathway)
Ascorbate biosynthesis, animals, glucose-1P => ascorbate
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Metabolism
  Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    394436 (Ugt1a1)
   00053 Ascorbate and aldarate metabolism
    394436 (Ugt1a1)
   00500 Starch and sucrose metabolism
    394436 (Ugt1a1)
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    394436 (Ugt1a1)
  Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    394436 (Ugt1a1)
   00860 Porphyrin and chlorophyll metabolism
    394436 (Ugt1a1)
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    394436 (Ugt1a1)
   00982 Drug metabolism - cytochrome P450
    394436 (Ugt1a1)
   00983 Drug metabolism - other enzymes
    394436 (Ugt1a1)
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    394436 (Ugt1a1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.17  glucuronosyltransferase
     394436 (Ugt1a1)
Glycosyltransferases [BR:mmu01003]
 Others
  Hydrophobic molecule
   394436 (Ugt1a1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
MGI: 
UniProt: 
Position
1 D; 1 44.55 cM
AA seq 535 aa AA seqDB search
MTVVCWSSRLLLLLPYLLLCVFGPSASHAGRLLVFPMDGSHWLSMLGVIQQLQQKGHEVV
VIAPEASIHIKEGSFYTLRKFPVPFQKENVTATLVELGRTAFNQDSFLLRVVKIYMKVKR
DSSMLLAGCSHLLHNAEFMASLEESHFDALLTDPFLPCGSIVAQYLTVPTVYFLNKLPCS
LDSEATQCPVPLSYVPKSLSFNSDRMNFLQRVKNVLLAVSENFMCRVVYSPYGSLATEIL
QKEVTVQDLLSPASIWLMRSDFVKDYPRPIMPNMVFIGGINCLQKKPLSQEFEAYVNASG
EHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQN
DLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEM
TADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAA
HDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH
NT seq 1608 nt NT seq  +upstreamnt  +downstreamnt
atgactgtggtgtgctggagctcgcgtttgcttctgcttcttccgtaccttctgttgtgt
gtgttcggtccctctgcatcccacgctgggaggctgttagtgttccctatggatggaagc
cactggctgagtatgcttggagttattcagcagctccagcagaaggggcacgaagttgtg
gtcatagcacctgaagcctcaatacacataaaagaaggatcattttacactctgaggaag
ttccctgtgccattccagaaggaaaatgtgacagctactttggtggaacttggacggact
gcctttaatcaagattcttttctgctgcgcgtggtcaaaatatatatgaaagtcaaaagg
gattccagtatgctcctagctggctgctcccacctgctgcacaatgccgagtttatggcc
tctctggaagaaagtcactttgatgctctgctgacagaccctttccttccctgtggctcc
attgtggcccagtacctgactgtgcccactgtgtacttcttgaataaattgccatgcagc
ctggattcagaagctacccaatgccccgtcccattgtcctacgtgcccaagagtttgtct
ttcaactcagaccgcatgaacttcctacagcgagtgaagaacgtgctcctggccgtgtca
gagaactttatgtgcagagtggtttattccccctatgggtcacttgccactgaaatctta
cagaaagaagtgactgtccaggatcttctgagccctgcatctatctggctgatgagaagt
gactttgtgaaagattaccccaggcccatcatgcccaacatggtttttattggtggtata
aattgccttcagaaaaagcccctatcccaggaatttgaagcctatgtcaacgcctctggg
gagcatggcatcgttgttttctctttgggatccatggtctcagagattccggagaagaaa
gccatggaaattgctgaggctttgggcagaattcctcagacggtcctgtggcgctacacc
ggaactagaccatcgaatcttgcaaagaacacaattcttgtcaaatggctaccccaaaat
gatctgcttggtcatccaaagactcgggcattcatcacacactctggctcccatggtatt
tatgaaggaatatgcaatggagttccgatggtgatgatgcccctatttggcgatcagatg
gacaatgccaagcgcatggaaactcggggagctggggtgaccctgaatgtccttgaaatg
actgctgatgatttggaaaatgcccttaaaactgtcatcaacaacaagagctacaaggag
aacatcatgcgcctctccagccttcacaaggaccgtcctatagagcctctggacctggct
gtgttctgggtggaatacgtgatgaggcacaagggggcaccacacctgcgcccggccgcc
catgacctcacctggtatcagtaccactccttggatgtgattggcttcctcctggccatt
gtgttgacagtggtcttcattgtctttaaatgttgtgcctatggctgccggaaatgcttt
gggggaaaggggcgagtgaagaaatcacacaaatccaagacccattga

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