KEGG   Mycobacterium abscessus subsp. bolletii GO 06: MYCMA_2218Help
Entry
MYCMA_2218        CDS       T02177                                 

Gene name
hemD
Definition
porphyrin biosynthesis protein hemD (EC:4.2.1.75)
Orthology
K13542  
uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
Organism
mmv  Mycobacterium abscessus subsp. bolletii GO 06
Pathway
Porphyrin and chlorophyll metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Module
Heme biosynthesis, glutamate => protoheme/siroheme
Brite
KEGG Orthology (KO) [BR:mmv00001]
 Metabolism
  Metabolism of cofactors and vitamins
   00860 Porphyrin and chlorophyll metabolism
    MYCMA_2218 (hemD)
Enzymes [BR:mmv01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     MYCMA_2218 (hemD)
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.75  uroporphyrinogen-III synthase
     MYCMA_2218 (hemD)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
complement(4037424..4039073)
Genome map
AA seq 549 aa AA seqDB search
MTRGRKKPGRILFVGSGPGDPGLLTVRARAVLTGATVAFTDPDVPQAVLDLVGSAVELPE
PAPAKPATGGDEAPAAANNEAAAEPPLTIDIRPALGDPADVAKTLVAEARSGVDVVRLVA
GDPLSIDSVLAEVHAVTRTQVAFEILPGLASSTAVPAYAGLPPGSAHTVADVRGDVDWAA
LAAAPGPLILHATPTHVPDAAKALIEHGLADQTLVAVTAQGTTCAQRTVETTLASLIDGV
PVDANDPHGPMTGALVLTIGRVVAGRSKLNWWESRALYGWTVLVPRTKDQAGEMSDKLVG
YGALPVEVPTIAVEPPRSPAQMERAVKGLVDGRYQWVVFTSTNAVRAVWEKFAEFGLDAR
AFSGVKIACVGQATADKVRAFGINPELVPAGEQSSLGLLDEFPPYDDVFDPVNRVLLPRA
DIATETLAEGLRERGWEIDDVTAYRTVRAAPPAAQTREMIKTGGFDAVCFTSSSTVRNLV
GIAGKPHARTIVACIGPKTAETAVEFGLRVDVQPETAAVGPLVEALAEHAARLRTEGALP
PPRKKSRRR
NT seq 1650 nt NT seq  +upstreamnt  +downstreamnt
atgaccagggggcgcaagaagccagggcgcattctgttcgttggttccggacctggagac
cccggtctgttgaccgtccgggcgcgcgcggtgctcacaggtgccacggtcgcgttcacc
gatcccgatgtgccgcaggcggtactcgatctcgtggggtcggcggtcgaacttcctgaa
cccgcgcccgccaaaccggcaacgggaggcgatgaggctcccgccgcggcgaataacgaa
gccgctgccgagccgccgctcaccatcgacattcgccccgccttgggtgatccggccgat
gtcgccaagacactcgtcgccgaggcccgcagcggtgtggacgtggtgcggttggtcgcc
ggcgacccactctcgatcgattcggtgctcgccgaggtccatgccgtcacgcggacccag
gtggcctttgaaatcctgcccggtctcgcttcgagcaccgcggtgcccgcctacgcgggc
ctgcccccgggctcggcccacaccgtggccgatgtgcgcggcgacgtggattgggcggcc
ctggccgctgctcccggcccgctgattctgcacgcgaccccgacgcatgtgcccgacgcc
gccaaggcgctcatcgagcatggcctggccgaccagactctggtcgcggtcaccgcgcag
ggcaccacgtgcgcacagcgcaccgtggagaccacactggcctcgctgatcgacggcgtc
ccggtggacgccaacgacccgcacgggccgatgaccggcgccctggtgctgacgatcggc
cgcgtggtcgccggccgctcgaagctgaactggtgggaaagccgtgccctgtacggctgg
accgtgttggtgccccgtaccaaggatcaagccggcgagatgagcgacaagctcgtcggg
tacggcgccttgcccgtcgaggtgccgaccattgccgtcgaacccccgcgcagtccggcc
caaatggaaagggctgtgaagggtttggtcgacggccggtaccagtgggtggtgttcacc
tccaccaacgcggtgcgtgccgtgtgggagaagttcgccgagttcggcctggacgcccgc
gccttctccggtgtgaagatcgcgtgtgtgggccaggcgaccgccgacaaggtgcgcgcc
ttcggcatcaacccggagctggttcctgccggtgagcagtcctcgctaggcctgctcgac
gagttcccgccctacgacgacgttttcgatccggtgaaccgggtgctgttgccgcgggcc
gacatcgccaccgagacccttgccgagggactgcgggaacgcggctgggagatcgacgac
gtgaccgcgtaccgcaccgtgcgcgcggccccgccggcggcgcagacccgcgagatgatc
aagaccggtgggttcgacgcggtctgcttcacatcgagctctacggttcgcaacctggtg
ggtatcgcgggcaagccgcatgcacgcaccattgtggcgtgcatcgggccgaaaaccgct
gagaccgcagtcgaattcgggttgcgagtggatgtgcagccggagacagcggccgtgggc
ccgctggtcgaggctctcgccgagcacgccgcccggctgcgcaccgaaggtgcactgccg
ccgccgcgcaagaagagccggcggagataa

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