KEGG   Mycobacterium smegmatis JS623: Mycsm_00565Help
Entry
Mycsm_00565       CDS       T02423                                 

Definition
uroporphyrinogen-III synthase (EC:4.2.1.75 2.1.1.107)
Orthology
K13542  
uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
Organism
msa  Mycobacterium smegmatis JS623
Pathway
Porphyrin and chlorophyll metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Module
Heme biosynthesis, glutamate => protoheme/siroheme
Brite
KEGG Orthology (KO) [BR:msa00001]
 Metabolism
  Metabolism of cofactors and vitamins
   00860 Porphyrin and chlorophyll metabolism
    Mycsm_00565
Enzymes [BR:msa01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     Mycsm_00565
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.75  uroporphyrinogen-III synthase
     Mycsm_00565
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
599754..601451
Genome map
AA seq 565 aa AA seqDB search
MTGHSGRGRKTKPGRITFVGSGPGDPGLLTTRARTVLANAALIFTDPDVPEAVLALAGSE
LPPPSGPEPAEAPKAADTGDKDSDHAAAANAAPLASAIPGGPDIRPALGDPAEVAKTLAT
EARTGVDVVRLVAGDPLSVDAVITEVTALAKTHLDFEIVPGLPDTTAVPTYAGLPLGSAH
TVADVRGDVDWAALAAAPGPLILHATASHLPDAARTLIEHGLIDTTPTVVTANGTTCQQR
SVETTLAGLLDKAVLDKPAGSEPAGPLAGPLVVTIGKTVANRAKLNWWESRALYGWTVLV
PRTKDQAGEMSEKLVGHGALPVEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNA
VRAVWEKFNEFGLDARAFSGVKIACVGQATADRVRAFGINPELVPSGEQSSLGLLDEFPP
YDDVFDPVNRVLLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPASTREMIKTGG
FDAVCFTSSSTVRNLVGIAGKPHARTIVACIGPKTAETAAEFGLRVDVQPEVAAIGPLVD
ALAEHAARLRAEGALPPPRKKSRRR
NT seq 1698 nt NT seq  +upstreamnt  +downstreamnt
atgactgggcactcgggcagagggcgtaagacaaagcccggccgcatcaccttcgtcggc
tccgggccgggtgaccccggcctgctgacgacgcgggcgcgaacggtcctcgccaatgcc
gcgcttattttcaccgatcccgacgtgccagaagcggtgctcgcccttgcgggttccgag
ctgccgccgccgtcgggacctgagcctgctgaggcgccgaaagccgccgacaccggggat
aaggactcagaccatgccgccgccgccaatgcggctccgctggcctcggccattccgggc
ggtcccgacatccggcccgcgctgggcgatcctgccgaggtcgcgaagacgctggccacc
gaggcacgtacgggtgtcgacgtggtccggttggtcgcgggcgacccgctgtcggtggat
gcggtgatcaccgaggtcaccgcgctggccaagacgcatttggatttcgagatcgtcccg
gggctacccgacaccaccgcggtgccgacgtatgcggggctgccgctgggatcggcgcac
acggtggccgacgtccgcggtgacgtggactgggcggcgctggccgccgcgcctggccca
ctgatcctgcacgcgaccgcatctcatctgccggacgcggcgcgcacactgatcgagcac
gggctgatcgacaccacgccaaccgtcgtgaccgcgaatggcacgacgtgccaacaacgt
tcggtcgaaacgactctcgctggcctgctcgacaaggctgtgcttgataagcctgcgggc
agcgagcctgccggtccattggccggcccgctggtggtgacaatcggcaagaccgtcgcc
aaccgcgcgaagctcaactggtgggagagccgcgccctgtacggctggaccgtgctggtg
ccgcgcaccaaggatcaggccggcgagatgagcgaaaagctggtcggccacggcgcattg
cctgtcgaggtgccgaccatcgcggtcgaaccgccgcgtagccccgcgcagatggagcgt
gcggtcaagggccttgtcgatggccggttccagtgggtggtgttcacctccaccaacgcg
gtgcgtgcggtgtgggagaagttcaacgagttcggccttgacgcccgcgcgttctcgggt
gtgaagatcgcgtgcgtcggccaggccaccgccgaccgggtgcgggccttcggtatcaac
ccggagctggtgccgtcgggcgagcaatcctcgctgggcctgcttgacgaattcccgccc
tacgacgacgttttcgatccggtgaaccgggtgctgttgccgcgtgcggacatcgccacc
gagacgctggccgaagggcttcgcgagcgtgggtgggagatcgaggacgtcacggcctat
cgcacggtgcgtgcggcgccgccgcccgcgtcgacccgcgagatgatcaagaccggtgga
ttcgacgcggtttgcttcacgtcgagctcgacggtacgcaacctggtgggtatcgccggc
aagccgcatgcgcgcaccatcgtcgcgtgcatcggcccgaaaactgctgaaacagcagcg
gaattcggtctgcgcgtcgatgtacagccagaagtcgccgccatcggcccgctggtcgac
gcgctggccgagcacgccgcccggctacgtgccgaaggcgcgctgccgccaccgcgcaag
aagagccgcaggcgctga

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