KEGG   Mycobacterium sp. JS623: Mycsm_02221
Entry
Mycsm_02221       CDS       T02423                                 
Name
(GenBank) DNA ligase, NAD-dependent
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
msa  Mycobacterium sp. JS623
Pathway
msa03030  DNA replication
msa03410  Base excision repair
msa03420  Nucleotide excision repair
msa03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:msa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    Mycsm_02221
   03410 Base excision repair
    Mycsm_02221
   03420 Nucleotide excision repair
    Mycsm_02221
   03430 Mismatch repair
    Mycsm_02221
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:msa03032]
    Mycsm_02221
   03400 DNA repair and recombination proteins [BR:msa03400]
    Mycsm_02221
Enzymes [BR:msa01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     Mycsm_02221
DNA replication proteins [BR:msa03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     Mycsm_02221
DNA repair and recombination proteins [BR:msa03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     Mycsm_02221
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Mycsm_02221
   MMR (mismatch excision repair)
    DNA ligase
     Mycsm_02221
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      Mycsm_02221
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT DNA_ligase_ZBD HHH_5 PTCB-BRCT HHH BRCT_2
Other DBs
NCBI-ProteinID: AGB22572
UniProt: L0IW65
Position
2187959..2190058
AA seq 699 aa
MSPKKPETVLAEQADDAPDADLRRRWQELADEVREHQFRYYVRDAPIISDAEFDKLLREL
QGLEDNHPELRTPDSPTQLVGGAGFATEFTQAEHLERMLSLDNVFSPDELAAWAARTKAE
IGDKAHYLCELKIDGVALALVYRDGRLERAATRGDGRTGEDVTLNARTIDDVPEKLTGSK
EFPVPAVLEVRGEVFFRVADFEDLNAGLVAEGKPPFANPRNSAAGSLRQKNPAVTARRKL
RMICHGLGHSEGFRPKTLHDAYRALAAWGLPVSEHTARVQGIDAVTEHIAYWGEHRHDVE
HEIDGVVVKVDEIALQRRLGSTSRAPRWAIAYKYPPEEATTKLLDIKVNVGRTGRVTPFA
FMEPVKVAGSTVSQATLHNASEVKRKGVLIGDTVVIRKAGDVIPEVLGPVVDLRDGSELE
FVMPTTCPECGTTLAPAKEGDADIRCPNTRSCPAQLRERVFHVAGRGAFDIEGLGYEAAT
ALLTSGVITDEGDLFTLGSPDLLRTDLFKTKDGNLSANGARLLVNLHEAKSRPLWRVLVA
LSIRHVGPTAARALATEYGSLDAVMAASQEELSVVEGVGPTIAAAVVEWFTVDWHRAIID
KWRAAGVRMADERDSSVERTLEGMSIVVTGSLTAYSRDDAKEAIVARGGKAASSVSKKTA
YVVAGDSPGSKYDKAVELGVPILDEDGFRRLLEHGPDGV
NT seq 2100 nt   +upstreamnt  +downstreamnt
gtgagtccgaagaagccggaaaccgtcctcgccgagcaggccgacgatgcccccgatgcc
gaccttcgccgccgttggcaagaactcgccgacgaggtgcgggagcatcagttccggtac
tacgtgcgcgacgcgccgatcatctccgacgcggagttcgacaagctgttgcgcgagctg
caggggctcgaggacaaccatccggaactgcgcacccctgactcgcccacccaactcgtc
ggcggtgcggggtttgccaccgaattcacccaggccgagcacctcgaacggatgctgtcg
ctggacaatgtcttctcgcccgatgagttggccgcctgggccgcccgcaccaaggccgag
atcggcgacaaggcgcactatctctgcgagctgaagatcgacggcgtggcgctggcgctg
gtgtatcgcgacggcaggctggaacgcgccgcgacccgcggtgacggccgcaccggtgag
gacgtcacgctcaacgcgcgcaccatcgacgacgtgcctgagaagctcaccgggtccaag
gagtttccggtacccgcggtccttgaggttcgcggcgaggttttcttccgtgtcgccgat
ttcgaagacctcaacgcgggccttgtcgccgagggcaagccgccgttcgcgaacccgcga
aacagtgcggcgggctcgctgcgacagaagaatccagccgtcactgctcgccgcaagctg
cggatgatctgccacggcctcggccactccgagggctttcggcccaagacgctgcacgat
gcctaccgcgcgctggcggcctggggactgccggtgtccgaacacaccgctcgtgtgcag
ggcatcgatgcggtcaccgaacacatcgcgtactggggtgagcaccggcacgacgtcgag
cacgaaatcgacggtgtggtggtcaaagtcgacgagatcgcgctgcagcgcaggctcggc
tcgacatcacgggcaccccgctgggccatcgcctacaaatacccgcccgaggaggccacc
accaaactgctcgacatcaaggtcaacgtcgggcgcaccggtcgcgtcacgccgttcgcg
ttcatggagccggtcaaggtcgccggctcgacggtcagccaggccacgctgcacaacgcg
tccgaggtcaagcgcaagggtgtgttgatcggcgacaccgtcgtcatccgcaaggccggc
gacgtgatccccgaggtgctgggtcccgtcgtcgatctgcgcgacggcagcgaactcgaa
ttcgtcatgcccacaacgtgtcccgaatgcggcaccacgctggcgcccgcgaaggagggc
gacgccgacatccgctgccccaacacccgatcgtgcccagcgcagctgcgggagagggtg
tttcacgtcgcggggcgcggcgcgttcgacatcgagggtctcggctacgaagcggccacc
gcgcttctgacgtcgggcgtcatcaccgacgagggagacctgttcaccctcggcagcccc
gacctgttgcgcaccgatctgttcaaaaccaaggacggcaacctgtcggccaacggcgca
cgactgttggtgaacctgcacgaggcgaagtcgcgtccgctgtggcgggtcctcgtcgca
ctgtcgatccggcatgtcggccccaccgctgcgcgcgcgctggccaccgaatacggcagc
ctcgacgcggtgatggcggcgtcgcaggaggagctgtccgtggtcgagggcgtcggtccg
accatcgccgctgctgttgtcgagtggttcaccgtcgactggcaccgcgcgatcatcgac
aagtggcgcgccgccggggtccggatggccgacgagcgcgacagcagcgtcgagcgcacg
ctcgagggcatgtcgatcgttgtcaccggatcgctcaccgcgtactcgcgcgacgatgcg
aaggaggccatcgtcgcgcgcggcggtaaggccgccagttcggtgtcgaagaagaccgcc
tatgtggtggccggcgattcaccgggctcgaagtacgacaaggccgtcgaactcggcgtg
ccgatcctcgacgaggacggctttcgcaggctgctcgaacacgggcccgacggagtctga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (9)   
   Pfam (9)   
All databases (29)   

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