KEGG   Mycobacterium stephanolepidis: MSTE_00433
Entry
MSTE_00433        CDS       T05257                                 
Symbol
topA
Name
(GenBank) DNA topoisomerase 1
  KO
K03168  DNA topoisomerase I [EC:5.6.2.1]
Organism
mste  Mycobacterium stephanolepidis
Brite
KEGG Orthology (KO) [BR:mste00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:mste03032]
    MSTE_00433 (topA)
   03400 DNA repair and recombination proteins [BR:mste03400]
    MSTE_00433 (topA)
Enzymes [BR:mste01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.1  DNA topoisomerase
     MSTE_00433 (topA)
DNA replication proteins [BR:mste03032]
 Prokaryotic type
  DNA Topoisomerases
   MSTE_00433 (topA)
DNA repair and recombination proteins [BR:mste03400]
 Prokaryotic type
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHIIR (short-homology-independent illegitimate recombination)
     Facilitator
      MSTE_00433 (topA)
SSDB
Motif
Pfam: Topoisom_bac Toprim_C_rpt Toprim Toprim_4
Other DBs
NCBI-ProteinID: BAX95776
UniProt: A0A1Z4ES37
Position
421908..424685
AA seq 925 aa
MRRLVIVESPTKARKIAGYLGDGYVVESSRGHIRDLPRAAADVPAKYKSEPWARLGVNVD
EDFEPLYIVSPDKKGTVTELKGLLKDVDELYLATDGDREGEAIAWHLLETLKPKVPVRRM
VFHEITEQAILAAAQDPRDLDNNLVDAQETRRILDRLYGYEVSPVLWKKVGRNLSAGRVQ
SVATRIIVQRERDRMAFRSAGYWDLGAELDAGSEAKPPRFNARLLSVDALRVASGRDFDS
LGQVKKADDVLVLDEVRANALVAGLAHATLTVASAEEKPYTRKPYPPFMTSTLQQEAGRK
LRFSSERTMSIAQRLYENGYITYMRTDSTTLSESALTAARSQAAELYGSEYVHPSPRQYT
RKVKNAQEAHEAIRPAGETFKTPGQLHSLIDNDEFRLYELIWQRTVASQMADARGTTLSL
RLAGTATSGEQVVFTASGRTITFPGFLSAYVETVDELAGGEADDEERRLPQLKQGQTVTV
AELSADGHTTNPPARYTEASLIKALEELGIGRPSTYSSIIRTIQDRGYVHKRGSALVPSW
TAFAVIGLLEQHFGRLVDYDFTAAMEDDLDEIASGNERRTNWLNAFYFGGEHGVEGSVAR
AGGLKRLVGVNLEEIDAREVNSIKLFDDDQGRPIYVRVGKNGPYLERMITGDDGEPTPQR
ANVKDGVTPDELTVEMAEQLFAIPQEGRTLGVDPESGHEIVAKDGRFGPYVTEVLPAPPE
QLDAAEAEVKPKRGAKKVEGPKPRTGSLLKSMTLETVTLEDALKLLSLPRVVGVDPANGE
EITAQNGRYGPYLKRGTDSRSLATEDQMFTITLDEALKIYSEPKRRGGQAASAAPLRELG
ADSATGKPMVIKDGRFGPYVTDGETNASLRKGDDVLSITDERASELLADRRARGPVKRVK
KAPAKAAKKAPAKKAPAKKAAKKAT
NT seq 2778 nt   +upstreamnt  +downstreamnt
gtgcgacggctcgtcatcgtcgaatcaccgacgaaggcccgcaagatcgctggctacctc
ggcgacggatacgtcgtcgagtcctcgcgtggccacatccgggacctgccccgtgccgct
gccgacgttccggccaagtacaagtccgaaccctgggctcgactcggagtgaacgtcgac
gaagacttcgagccgctctacatcgtcagccccgacaagaagggcaccgtcaccgagctg
aagggcctgctgaaggacgttgacgagctctatctcgcaacggacggtgaccgcgagggt
gaggccatcgcctggcacctgctcgagactctcaagcccaaggtgcccgtcaggcgcatg
gtcttccacgagatcaccgagcaagccatcctggcggccgctcaggacccccgtgacctc
gacaacaacctcgtcgacgcacaggagacccgccgcatcctggaccggctctacggctac
gaggtcagtcccgtgctgtggaagaaggtcggccggaatctgtccgccgggcgcgtgcaa
tcggtggcgacccggatcatcgtccagcgcgaacgcgatcgcatggcgttccgcagcgcc
ggatactgggatctgggcgccgaactggacgccggcagcgaggccaagcctccgcgtttc
aacgcccgcctgctgagcgttgacgcgctgcgcgtggcttccggtcgcgacttcgactcg
ctgggccaggtcaagaaggccgacgatgtgctggttctcgacgaggtgcgggccaacgct
ctggtcgccgggctggctcatgccaccctgacagtcgcctcggccgaggaaaagccatac
acccgtaagccctacccgccgttcatgacatcgacgctgcagcaggaagccgggcgcaag
ctgcggttctcctccgagcgcaccatgagcattgcgcagcggctgtatgaaaacggctac
atcacctatatgcgtaccgattccacgacgctgtccgaatcggcattgactgccgcgcgc
agccaggccgcggagttgtacggaagcgaatatgtgcatccctcgccacggcaatacacg
cgcaaggtgaaaaatgcgcaggaagcgcacgaggctattcgtcccgcaggcgagactttc
aaaactccgggacaattgcattcactgatcgacaatgacgaattccgtctgtacgagctg
atctggcaacgcacggttgcctcgcagatggccgatgcacgcgggaccacgctgagcctg
cgattggccggcaccgccacctcgggtgagcaggtggtgttcaccgccagcggccgcacc
atcaccttccccggcttcttgtcggcgtacgtcgagaccgtggatgagctggccggtggc
gaggcagacgacgaggagcgtcgtctgccacagctcaagcagggccagaccgtcacggtc
gcggagctgtccgcagacggccacaccaccaatccgcctgcccgatacaccgaagcctcg
ctcatcaaggcattggaagagttggggattgggcgtccgtcgacctactcctcgatcatc
cggaccatccaggaccgcggctacgtgcacaagcgcggcagtgcgctggtgccctcatgg
accgcgttcgcggtgatcggtctgctggagcaacacttcggccggctggtcgactacgac
ttcaccgccgcgatggaggatgacctcgacgagatcgcctccggcaacgaacggcgcaca
aactggttgaacgccttctattttggtggcgagcacggtgtcgagggttcagtagcccgc
gccggcggactcaagcgcctggtgggggtgaacctcgaggagatcgatgcccgcgaggtc
aactcgatcaagctgttcgacgatgaccagggtcgccccatctacgtgcgggtcggaaag
aacggcccgtacctggaacggatgatcaccggcgacgacggggaaccgaccccgcagcgc
gccaacgtcaaggacggcgtcacccccgatgagctgaccgtcgagatggctgagcagctg
ttcgcgatcccacaggagggccggacgctgggtgttgacccggagtccggacacgaaatc
gtcgccaaggatggacgtttcggcccttacgtcaccgaggtgctgcctgcaccgccggag
cagctggacgccgccgaggccgaggtgaagcccaagcggggcgccaagaaggtagaaggg
cccaagccgcgtaccggctcactgctgaagtccatgacgttggagacggtgacgctcgag
gacgcgctcaagctgctgtcattgccgcgcgtggtcggtgtcgatccggccaacggagaa
gagatcaccgcgcagaacgggcgttacggcccatacctcaagcgcggcaccgattctcga
tcgcttgccaccgaggatcagatgttcaccatcaccctcgatgaggcgctgaagatctac
tccgagcccaaacgtcgtggcggtcaggcggcttcggcggctccgctacgtgagcttggt
gcggattcggcgaccggcaaaccgatggtgatcaaggacggccgcttcggcccgtacgtc
accgacggtgagaccaacgccagcctgcgtaagggtgatgacgtgctgtcgatcaccgat
gagcgtgcctcggagttgcttgccgaccgtcgggcccgtgggcctgtgaagcgcgtcaag
aaggcgcctgcgaaggcggcaaagaaggctcccgccaagaaggccccggcgaagaaggcc
gccaagaaggcgacctag

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Ontology (4)   
   KEGG BRITE (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (4)   
   Pfam (4)   
All databases (14)   

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