KEGG   Mycobacterium tuberculosis KZN 1435: TBMG_00956
Entry
TBMG_00956        CDS       T00940                                 
Name
(GenBank) NAD-dependent DNA ligase ligA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
mtb  Mycobacterium tuberculosis KZN 1435
Pathway
mtb03030  DNA replication
mtb03410  Base excision repair
mtb03420  Nucleotide excision repair
mtb03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:mtb00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    TBMG_00956
   03410 Base excision repair
    TBMG_00956
   03420 Nucleotide excision repair
    TBMG_00956
   03430 Mismatch repair
    TBMG_00956
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:mtb03032]
    TBMG_00956
   03400 DNA repair and recombination proteins [BR:mtb03400]
    TBMG_00956
Enzymes [BR:mtb01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     TBMG_00956
DNA replication proteins [BR:mtb03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     TBMG_00956
DNA repair and recombination proteins [BR:mtb03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     TBMG_00956
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     TBMG_00956
   MMR (mismatch excision repair)
    DNA ligase
     TBMG_00956
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      TBMG_00956
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT DNA_ligase_ZBD HHH_5 PTCB-BRCT HHH BRCT_2 Auto_anti-p27 Bactofilin
Other DBs
NCBI-ProteinID: ACT23997
Position
1039810..1041234
AA seq 474 aa
MRQKDPAVTARRRLRMICHGLGHVEGFRPATLHQAYLALRAWGLPVSEHTTLATDLAGVR
ERIDYWGEHRHEVDHEIDGVVVKVDEVALQRRLGSTSRAPRWAIAYKYPPEEAQTKLLDI
RVNVGRTGRITPFAFMTPVKVAGSTVGQATLHNASEIKRKGVLIGDTVVIRKAGDVIPEV
LGPVVELRDGSEREFIMPTTCPECGSPLAPEKEGDADIRCPNARGCPGQLRERVFHVASR
NGLDIEVLGYEAGVALLQAKVIADEGELFALTERDLLRTDLFRTKAGELSANGKRLLVNL
DKAKAAPLWRVLVALSIRHVGPTAARALATEFGSLDAIAAASTDQLAAVEGVGPTIAAAV
TEWFAVDWHREIVDKWRAAGVRMVDERDESVPRTLAGLTIVVTGSLTGFSRDDAKEAIVA
RGGKAAGSVSKKTNYVVAGDSPGSKYDKAVELGVPILDEDGFRRLLADGPASRT
NT seq 1425 nt   +upstreamnt  +downstreamnt
ctgcgccagaaagacccggcggtcaccgcgcgccgccggctgcggatgatctgccacggg
ctgggccacgtggagggctttcgcccggccaccctgcatcaggcatacctggcgttgcgg
gcatggggactgccggtttccgaacacaccaccctggcaaccgacctggccggtgtgcgc
gagcgcatcgactactggggcgagcaccgccacgaggtggaccacgaaatcgacggcgtg
gtggtcaaagtcgacgaggtggcgttgcagcgcaggctgggttccacgtcgcgggcgccg
cgctgggccatcgcctacaagtacccgcccgaggaagcgcagaccaagctgctcgacatc
cgggtgaacgtcggccgcaccgggcggatcacgccgtttgcgttcatgacgccggtgaag
gtggccgggtcgacggtgggacaggccaccctgcacaacgcctcggagatcaagcgcaag
ggcgtgctgatcggcgacaccgtggtgatccgcaaggccggcgacgtgatccccgaggtg
ctgggacccgtcgtcgaactgcgcgatggctccgaacgcgaattcatcatgcccaccacc
tgcccggagtgcggttcgccgttggcgccggagaaggaaggcgacgccgacatccgttgc
cccaacgcccgcggctgcccggggcaactgcgggagcgggttttccacgtcgccagccgc
aacggcctagacatcgaggtgctcggttacgaggcgggtgtggcgctcttgcaggcgaag
gtgatcgccgacgagggcgagctgttcgcgctgaccgagcgggacttgctgcgcaccgac
ctgttccgaaccaaggcaggcgaactgtcggccaacggcaaacggctgctggtcaacctc
gacaaggccaaggcggcaccgctgtggcgggtgctggtggcgctgtccatccgccatgtc
gggccgacggcggcccgcgccctggccaccgagttcggcagccttgacgccatcgccgcg
gcgtccaccgaccagctggccgccgtcgagggggtggggccgaccattgccgccgcggtc
accgagtggttcgccgtcgactggcaccgcgagatcgtcgacaagtggcgggccgccggg
gtgcgaatggtcgacgagcgtgacgagagtgtgccacgcacgctggccgggctgaccatc
gtggtcaccggctcgctgaccggtttctcccgcgacgacgccaaggaggcgatcgtggcc
cgcggcggcaaggccgccggctcggtgtcgaagaagaccaactatgtcgtcgccggagac
tcgccgggatccaaatacgacaaggcggtggagttgggggtgccgattctggacgaggat
gggttccggagactgctggccgacggacccgcgtcacgaacgtaa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (11)   
   Pfam (11)   
All databases (30)   

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