KEGG T00940: TBMG

Mycobacterium tuberculosis KZN 1435: TBMG_01212

Entry

TBMG_01212 CDS T00940

Definition

dihydrofolate reductase dfrA

Orthology

K00287

dihydrofolate reductase [EC:1.5.1.3]

Organism

mtb Mycobacterium tuberculosis KZN 1435

Pathway

mtb00670	One carbon pool by folate
mtb00790	Folate biosynthesis
mtb01100	Metabolic pathways

Class

Metabolism; Metabolism of cofactors and vitamins; Folate biosynthesis [PATH:mtb00790]
Metabolism; Metabolism of cofactors and vitamins; One carbon pool by folate [PATH:mtb00670]

SSDB

Motif

Pfam:

DHFR_1

Other DBs

NCBI-GI:

253798155

NCBI-GeneID:

8164612

UniProt:

C6DLE4

Structure

PDB:

1DF7 1DG7 1DG5 1DG8 2CIG

Position

1341401..1341886

AA seq 161 aa
MTMVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLP
GRRNVVLSRQADFMASGAEVVGSLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIG
LPREAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS

NT seq 486 nt +upstreamnt +downstreamnt
gtgacgatggtggggctgatctgggctcaagcgacatcgggtgtcatcggccgcggcggc
gacatcccctggcgcttgcccgaggaccaggcgcatttccgggagatcaccatggggcac
acgatcgtgatgggccggcgcacatgggattcgctgccggctaaagtccggccgctgccc
ggccggcgaaatgtcgtactgagccgccaagctgactttatggccagcggggctgaggtt
gtcggttcactcgaggaggcgctgaccagcccggagacgtgggtgatcggaggcggacaa
gtctatgcgctggcgctgccgtacgcgaccagatgtgaggttaccgaggtcgacatcggc
ctgccgcgcgaagccggtgacgcgctggcccccgtgctggacgagacatggcggggcgag
acgggggagtggcgcttcagccggtccgggttgcggtaccggttgtacagctaccaccgc
tcatga

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (7)   
   KEGG ENZYME (1)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
3D Structure (5)   
   PDB (5)   
Protein domain (1)   
   Pfam (1)   
All databases (31)   

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