KEGG T01992: CCDC5180

Mycobacterium tuberculosis CCDC5180: CCDC5180_2271

Entry

CCDC5180_2271 CDS T01992

Definition

branched-chain alpha-keto acid dehydrogenase subunit E2

Orthology

K00627

pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12]

Organism

mtl Mycobacterium tuberculosis CCDC5180

Pathway

mtl00010	Glycolysis / Gluconeogenesis
mtl00020	Citrate cycle (TCA cycle)
mtl00620	Pyruvate metabolism
mtl01100	Metabolic pathways
mtl01110	Biosynthesis of secondary metabolites
mtl01120	Microbial metabolism in diverse environments

Module

mtl_M00307

Pyruvate oxidation, pyruvate => acetyl-CoA

Class

Metabolism; Carbohydrate metabolism; Glycolysis / Gluconeogenesis [PATH:mtl00010]
Metabolism; Carbohydrate metabolism; Citrate cycle (TCA cycle) [PATH:mtl00020]
Metabolism; Carbohydrate metabolism; Pyruvate metabolism [PATH:mtl00620]

SSDB

Motif

Pfam:

2-oxoacid_dh Biotin_lipoyl E3_binding GCV_H Biotin_lipoyl_2

Other DBs

NCBI-GI:

385991805

NCBI-GeneID:

12500135

UniProt:

F7WVQ3

Structure

PDB:

3L60

Position

complement(2796965..2798113)

AA seq 382 aa
MPDLGEGLQEVTVTCWSVAVGDDVEINQTLCSVETAKAEVEIPSPYAGRIVELGGAEGDV
LKVGAELVRIDTGPTAVAQPNGEGAVPTLVGDGADAAIETSRRTSRPLAAPVVRKLAKEL
AVDLAALQRGSGAGGVITRADVLAAARGGVGAGPDVRPVHGVHARMAEKMTLSHKEIPTA
KASVEVICAELLRLRDRFVSAAPEITPFALTLRLLVIALKHNVILNSTWVDSGEGPQVHV
HRGVHLGFGAATERGLLVPVVTDAQDKNTRELASRVAELITGAREGTLTPAELRGSTFTV
SNFGALGVDDGVPVINHPEAAILGLGAIKPRPVVVGGEVVARPTMTLTCVFDHRVVDGAQ
VAQFMCELRDLIESPETALLDL

NT seq 1149 nt +upstreamnt +downstreamnt
gtgcccgacctcggcgagggactgcaggaagtgacggtgacgtgttggagcgtcgccgtc
ggcgacgatgtggagatcaaccagacgctgtgttcggtggagaccgccaaggccgaggtc
gaaatccccagcccgtatgccggccggatcgtcgagttaggcggcgccgaaggcgatgtg
ctcaaagtgggcgcggagctagttcggatcgacaccgggcccacggcagttgcgcagcct
aacggtgaaggagcggtccccacgttggtcggcgacggtgccgacgccgcgatcgaaacc
agtagacggacaagccggccgctggcggcaccggtagtgcgcaagctggccaaagagttg
gcggtcgacctggccgcattgcagcgtgggtcgggcgccggcggtgtgatcacccgggcc
gatgtgctggccgctgctcgaggcggcgtcggagccgggccggacgtgcggccggtccac
ggcgtgcacgcgcggatggccgaaaaaatgacgttgtcccacaaggagattccgaccgca
aaggccagcgttgaggtaatttgcgccgaactgctgcggctgcgcgaccggttcgtttcg
gcggcgcccgagattacaccgttcgcgctgacgctgcggctgctggttattgcattgaaa
cacaacgtaattctcaactcgacgtgggtcgactcgggcgaaggcccgcaagtacacgtg
catcgcggtgtgcatctggggttcggcgcggccactgagcgtggattgctggtgccggtg
gtgaccgacgcccaggacaagaacacccgcgaacttgcctcccgcgtagcggaattaatc
accggcgcacgtgaaggcactctcacacccgcggagctgcgcggttcgacgttcacggtg
tcgaacttcggggcgctgggagtcgacgacggcgtgccggtgatcaaccatcccgaagcg
gcgatcctgggtctgggggcgatcaagccgcgcccggtggtcgtcggcggcgaggttgtc
gcacggccgacgatgacgttgacttgtgtgttcgaccaccgcgttgtcgatggtgctcag
gtggcccagttcatgtgtgagctgcgggatctgatcgagtcgccggagaccgcgctgttg
gatctgtag

All links

Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
3D Structure (1)   
   PDB (1)   
Protein domain (5)   
   Pfam (5)   
All databases (26)   

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