KEGG T01993: MTCTRI2

Mycobacterium tuberculosis CTRI-2: MTCTRI2_0068

Entry

MTCTRI2_0068 CDS T01993

Gene name

icd2

Definition

isocitrate dehydrogenase

Orthology

K00031

isocitrate dehydrogenase [EC:1.1.1.42]

Organism

mto Mycobacterium tuberculosis CTRI-2

Pathway

mto00020	Citrate cycle (TCA cycle)
mto00480	Glutathione metabolism
mto01100	Metabolic pathways
mto01110	Biosynthesis of secondary metabolites
mto01120	Microbial metabolism in diverse environments
mto01210	2-Oxocarboxylic acid metabolism
mto01230	Biosynthesis of amino acids

Module

mto_M00010

Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate

Class

Metabolism; Carbohydrate metabolism; Citrate cycle (TCA cycle) [PATH:mto00020]
Metabolism; Metabolism of other amino acids; Glutathione metabolism [PATH:mto00480]

SSDB

Motif

Pfam:

IDH

Other DBs

NCBI-GI:

385996837

NCBI-GeneID:

12505236

UniProt:

G2N3C8

Position

complement(72312..74549)

AA seq 745 aa
MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE
EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ
EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH
GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE
QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS
DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR
AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE
EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLAVTRA
RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD
TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN
HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR
GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA
PDSDMTTAVMRPSKTFNAALEAVQG

NT seq 2238 nt +upstreamnt +downstreamnt
atgagcgccgaacagccgaccatcatttacacgctgaccgacgaggcgccgctgctggcg
acctacgcctttctgccgattgtgcgtgcctttgccgaaccggcgggcatcaagatcgag
gccagcgacatctctgtagcggcacgcatcctggcggaattccccgattacctgaccgag
gagcagcgggtaccggataacctcgccgaactgggccggctgactcagctacccgacacc
aacatcatcaagctgccgaacatcagcgcctcggtgccacagctggtagccgccatcaag
gaactgcaagacaagggttacgcggtcccagactacccggcggacccgaagactgaccag
gagaaggccatcaaagagcgctacgccagatgcctgggcagcgcggtgaacccggtactg
cgccaaggcaattcggaccgtcgggcgcccaaagcggtgaaggagtacgcgcgcaagcac
ccgcacagcatgggcgagtggtcgatggcctcacgcacccacgtagcgcacatgcggcac
ggtgacttctacgccggcgagaagtcgatgacactggaccgcgcgcgcaacgtgaggatg
gaactgctggccaagagcggcaagacgatcgtgctcaagcccgaggtgccgctggatgac
ggcgacgtcatcgacagcatgttcatgagcaagaaagcgctgtgcgacttctacgaagag
cagatgcaggatgcgttcgagaccggcgtgatgttctccttgcacgtcaaggcgaccatg
atgaaggtcagccaccccatcgtcttcggccacgcggtcaggatcttctacaaggacgcc
ttcgccaagcaccaggagctgttcgacgacttgggcgtcaacgtcaacaatggcttgtcc
gatctgtacagcaagatcgagtcgctgccggcgtcgcaacgcgacgagatcatcgaggac
ctacaccgttgccacgaacaccgccccgagctcgcgatggtcgattcggccagaggtatc
tccaacttccactcgccgagcgatgtgatcgtggacgcctcgatgcccgcgatgattcgc
gcgggcggcaagatgtatggcgccgacggaaagctcaaggacaccaaggcggtcaacccg
gagtccaccttctcgcgcatctatcaggagatcatcaacttctgcaagacaaatggccag
ttcgatccgacgacgatgggcaccgtccccaatgtgggtctgatggcccagcaggccgag
gagtacggctcgcacgacaagacgttcgagattcccgaggacggcgtcgccaacatcgtc
gatgtcgccaccggcgaggtgctgctgaccgagaacgtggaagccggcgacatctggcgc
atgtgcatcgtcaaggacgcaccgatccgtgactgggtcaagctggctgtcacccgcgcg
cgcatctccgggatgccggtgctgttctggctggacccgtaccgcccgcacgagaacgag
ctgatcaagaaggtcaagacatacctgaaagatcacgacaccgaaggtctggacatccag
atcatgtcgcaagtgcgatccatgcgctacacgtgcgagcgcctggtccgtggactggac
accatcgccgcgaccggcaacatcctgcgcgactacctcaccgacctgttcccgatcctg
gagttaggcaccagcgccaagatgctgtccgtcgttccgctgatggccggcggcggaatg
tacgagacgggggcgggcggttcggcacccaagcacgtcaaacaattggtggaggagaat
cacctgcgctgggattctctgggtgagttcctcgcgctgggcgccggtttcgaggatatc
ggcatcaagaccggtaacgagcgggccaaactcttgggtaagaccctggatgccgccatc
ggcaagctgctggacaacgacaagagtccgtcgcgcaaaaccggtgaactcgacaaccgg
ggcagccagttctacctcgccatgtactgggcacaagagctggccgcgcagaccgacgac
cagcagctggccgaacacttcgcctcgctggcagatgtgttgaccaaaaacgaagacgtc
atcgtgcgagagctcaccgaggtacaaggcgaaccggtggacatcggcggctactacgcg
ccggacagcgacatgactacggcggtgatgcggcccagcaagacgttcaatgcagcgctg
gaggctgtccaaggctga

All links

Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
Protein domain (1)   
   Pfam (1)   
All databases (27)   

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