| Entry |
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| Gene name |
ilvD
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| Definition |
(RefSeq) dihydroxy-acid dehydratase
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| KO |
| dihydroxy-acid dehydratase [EC: 4.2.1.9] |
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| Organism |
mtu Mycobacterium tuberculosis H37Rv
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| Pathway |
| Valine, leucine and isoleucine biosynthesis | | Pantothenate and CoA biosynthesis | | Metabolic pathways | | Biosynthesis of secondary metabolites | | Biosynthesis of antibiotics | | 2-Oxocarboxylic acid metabolism | | Biosynthesis of amino acids |
|
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| Module |
| Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine | | Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine |
|
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| Brite |
KEGG Orthology (KO) [BR:mtu00001]
Metabolism
Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Rv0189c (ilvD)
Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
Rv0189c (ilvD)
Enzymes [BR:mtu01000]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
Rv0189c (ilvD)
 |
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| SSDB |
    |
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| Motif |
 |
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| Other DBs |
NCBI-GeneID: NCBI-ProteinID: TubercuList: UniProt: |
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| Position |
complement(219996..221723)
 |
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| AA seq |
575 aa  
MPQTTDEAASVSTVADIKPRSRDVTDGLEKAAARGMLRAVGMDDEDFAKPQIGVASSWNE
ITPCNLSLDRLANAVKEGVFSAGGYPLEFGTISVSDGISMGHEGMHFSLVSREVIADSVE
VVMQAERLDGSVLLAGCDKSLPGMLMAAARLDLAAVFLYAGSILPGRAKLSDGSERDVTI
IDAFEAVGACSRGLMSRADVDAIERAICPGEGACGGMYTANTMASAAEALGMSLPGSAAP
PATDRRRDGFARRSGQAVVELLRRGITARDILTKEAFENAIAVVMAFGGSTNAVLHLLAI
AHEANVALSLQDFSRIGSGVPHLADVKPFGRHVMSDVDHIGGVPVVMKALLDAGLLHGDC
LTVTGHTMAENLAAITPPDPDGKVLRALANPIHPSGGITILHGSLAPEGAVVKTAGFDSD
VFEGTARVFDGERAALDALEDGTITVGDAVVIRYEGPKGGPGMREMLAITGAIKGAGLGK
DVLLLTDGRFSGGTTGLCVGHIAPEAVDGGPIALLRNGDRIRLDVAGRVLDVLADPAEFA
SRQQDFSPPPPRYTTGVLSKYVKLVSSAAVGAVCG |
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| NT seq |
1728 nt  +upstreamnt +downstreamnt
atgccgcaaaccaccgacgaagccgcttccgtctcgacggtcgccgacatcaagccccgc
agtcgagacgtcaccgacggcctggagaaggccgctgcccggggcatgttgagggcggtg
ggcatggacgacgaagacttcgcgaagccacagatcggggtcgcgtcgtcgtggaacgaa
atcacgccgtgcaatctctcattggaccggctggccaacgcggtcaaggagggggtgttt
tcggccggcggctatccgcttgagttcggcacgatctcggtttcggacggcatctccatg
ggtcatgaggggatgcacttctcgctggtttcccgtgaggtgatcgccgacagcgtcgaa
gtcgtgatgcaggccgaacgactcgacggttcggtgctgctggccggatgcgacaaatcg
ctgcccggaatgctgatggccgccgcacgactggatctggcggcggtgttcctctacgcg
ggctctattttgcccggccgggccaagctctccgacggtagcgaacgagacgtcaccatc
attgacgccttcgaggcggtcggagcgtgctctcgcggtttgatgagtcgcgccgacgtc
gatgccatcgagcgggcaatctgccccggcgaaggggcatgcggcggcatgtacaccgct
aacaccatggccagcgccgccgaggcgctcggcatgtcgttgccgggcagcgcggcaccg
ccggcgaccgaccgccggcgcgacgggttcgcgcgtcgcagcggtcaggccgtcgtcgag
ctgctgcgccgcggcatcaccgcccgcgacatcctcaccaaggaggcgttcgagaacgcc
atcgcggtggtaatggcgttcggcggctcgaccaacgcggtgctgcatctgctggccatc
gcccacgaggccaacgtcgcactatcgcttcaggacttcagccggatcgggtcgggggtg
ccgcatttggccgatgtcaagccgttcggccgccatgtgatgtccgacgtcgatcacatc
ggcggtgtgccggtggttatgaaggcgctgctggacgccggtctgctacacggcgactgc
ctgacggttaccggtcacaccatggccgagaatctggctgccatcaccccgccggatcca
gatggcaaggtgctacgtgcgttggcaaacccgatccacccgagcggtggcatcaccatc
ctgcacggatcgctggcacccgaaggtgcggtggtcaagaccgccggattcgattccgac
gtattcgaaggcaccgcaagagttttcgacggcgagcgcgctgcgctggacgcccttgag
gatggcaccattaccgtgggcgacgccgtggtaatccggtacgaaggacccaagggcggc
cccgggatgcgcgaaatgctcgccatcacaggcgcgatcaaaggcgcaggactcggtaaa
gatgttctactgctgaccgacggccggttctccggtggaaccaccggcctgtgcgttggc
cacatcgcaccggaggcggtcgacggcggaccgatcgcacttctgcgcaacggcgaccgg
atccggctcgacgtggccggccgcgttctcgatgtgttggccgatccggccgaattcgcg
tcccgacaacaggatttcagtcctccaccgccgcgctacactactggcgtactgtccaag
tacgtcaagctggtcagctctgccgcggtcggcgcggtctgcggctag |
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