KEGG   Mycobacterium tuberculosis H37Rv: Rv2157c
Entry
Rv2157c           CDS       T00015                                 
Symbol
murF
Name
(RefSeq) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
mtu  Mycobacterium tuberculosis H37Rv
Pathway
mtu00300  Lysine biosynthesis
mtu00550  Peptidoglycan biosynthesis
mtu01100  Metabolic pathways
mtu01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:mtu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    Rv2157c (murF)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    Rv2157c (murF)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    Rv2157c (murF)
Enzymes [BR:mtu01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     Rv2157c (murF)
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C Mur_ligase
Other DBs
NCBI-GeneID: 887826
NCBI-ProteinID: NP_216673
TubercuList: Rv2157c
UniProt: P9WJL1
Position
complement(2417472..2419004)
AA seq 510 aa
MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH
AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV
AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR
TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH
SGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAE
VRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDD
AYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVS
RLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGD
VVLVKASNAAGLGAVADALVADDTCGSVRP
NT seq 1533 nt   +upstreamnt  +downstreamnt
atgatcgagctgaccgtcgcgcagatcgccgagatcgtcgggggcgcagtggccgatatc
tccccgcaagacgccgcgcaccgccgcgtcaccgggaccgtcgagttcgactcgcgcgcc
atcggcccgggcgggctgttcctcgccctgccgggggcgcgcgccgacggccacgaccat
gccgcgtcggcggtagccgcgggcgccgccgtcgtgctggccgcccgcccggtgggggtg
ccggccatcgtggttccgccagtggccgcgccgaacgtattggccggcgtcctcgagcac
gacaacgacgggtcgggggcggcggtgctggccgcgctggccaagctggccaccgcggtg
gccgcgcagttggtggccggcgggctcaccatcatcgggatcaccggctcgtcgggcaag
acgtcgaccaaggacctgatggccgccgtgctggccccgctgggggaggtggtggccccg
cccggatcgttcaacaacgagctgggtcacccgtggacggtgctgcgcgcgacgcggcgc
accgactacctgattttggagatggcggcacgccatcacggcaacatcgccgcgctcgcc
gagatcgcgcccccgtcgatcggagtcgtgctcaacgtcggcaccgcacatttgggtgag
ttcggctcccgcgaggtcatcgcacagaccaaagccgaactgccgcaggctgttccgcat
tccggagcggtcgtcctcaacgctgatgaccccgcggtggcggcgatggccaagctgacc
gcggcccgggtggtgcgggtcagccgggacaacaccggtgacgtttgggcggggccggtg
tcgctggacgaattggccaggccgcgctttacgctgcatgcccacgatgcccaagccgag
gtccgactcggggtctgcggcgaccaccaggtcactaacgcgctgtgcgccgcggcggtc
gcgctggagtgtggggccagcgttgaacaggtcgcggccgcgctgaccgcggcgccgccg
gtgtcgcggcatcggatgcaggtgaccacccgcggcgacggggtgacggtgatcgacgac
gcctacaacgccaaccccgactccatgcgggccgggctgcaggcgctggcctggatcgcg
caccaacccgaggccacccgccgcagctgggcggtgctgggtgagatggccgagctgggt
gaggacgcgatagccgagcacgatcgcatcggccggctcgcggtgcgcttagatgtgtct
cgactcgttgtcgtgggaaccgggaggtcgatcagcgccatgcaccacggagcggtcctg
gagggggcgtggggctcgggggaagccactgctgatcacggtgcggatcgcacggccgtc
aatgtggccgacggtgacgccgccctggcactactgcgcgccgagctgcgacccggggat
gtggtcttggtcaaggcctcgaacgcggccgggctgggtgcggtggccgatgcattggtc
gcagacgacacatgcgggagtgtgcgcccatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   TUBERCULIST (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
Protein domain (3)   
   Pfam (3)   
All databases (37)   

Download RDF
DBGET integrated database retrieval system