KEGG   Mycobacterium tuberculosis H37Rv: Rv2847cHelp
Entry
Rv2847c           CDS       T00015                                 

Gene name
cysG
Definition
(RefSeq) multifunctional uroporphyrin-III C-methyltransferase/precorrin-2 oxidase/ferrochelatase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
mtu  Mycobacterium tuberculosis H37Rv
Pathway
mtu00860  Porphyrin and chlorophyll metabolism
mtu01100  Metabolic pathways
mtu01110  Biosynthesis of secondary metabolites
mtu01120  Microbial metabolism in diverse environments
Module
mtu_M00846  Siroheme biosynthesis, glutamate => siroheme
Brite
KEGG Orthology (KO) [BR:mtu00001]
 Metabolism
  Metabolism of cofactors and vitamins
   00860 Porphyrin and chlorophyll metabolism
    Rv2847c (cysG)
Enzymes [BR:mtu01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     Rv2847c (cysG)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     Rv2847c (cysG)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     Rv2847c (cysG)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif
Pfam: TP_methylase NAD_binding_7 2-Hacid_dh_C
Motif
Other DBs
NCBI-GeneID: 887481
NCBI-ProteinID: NP_215025
TubercuList: Rv2847c
UniProt: L0TDJ1 I6X5I7
Position
complement(3154654..3155871)
Genome map
AA seq 405 aa AA seqDB search
MTENPYLVGLRLAGKKVVVVGGGTVAQRRLPLLIASGADVHVIAPSVTPAVEAMDQITLS
VRDYRDGDLDGAWYAIAATDDARVNVAVVAEAERRRIFCVRADIAVEGTAVTPASFSYAG
LSVGVLAGGEHRRSAAIRSAIREALQQGVITAQSSDVLSGGVALVGGGPGDPELITVRGR
RLLAQADVVVADRLAPPELLAELPPHVEVIDAAKIPYGRAMAQDAINAVLIERARSGNFV
VRLKGGDPFVFARGYEEVLACAHAGIPVTVVPGVTSAIAVPAMAGVPVTHRAMTHEFVVV
SGHLAPGHPESLVNWDALAALTGTIVLLMAVERIELFVDVLLKGGRTADTPVLVVQHGTT
AAQQTLRATLADTPEKVRAAGIRPPAIIVIGAVVGLSGVRGLNNS
NT seq 1218 nt NT seq  +upstreamnt  +downstreamnt
gtgaccgagaacccctatctggtcgggttacggctggctggcaagaaggtcgtcgtggtt
ggcgggggcacggtcgcccagcgccggttacccctgctgatcgccagtggcgcggacgtg
cacgtgatcgcccccagcgtcacccccgccgtcgaggcgatggaccagatcaccttgtcg
gtgcgtgactaccgcgacggcgaccttgacggcgcctggtatgcgatcgcggccaccgat
gacgcgcgggtgaacgtggctgtcgtcgccgaggcggagcgccgacggatcttttgcgtc
cgggccgatatcgcggtggaggggacggcggtgaccccggcgtcattcagctatgcgggc
ctgtcggtgggggtgctcgccggtggtgagcaccgccgttcggcggcgatccgctcggca
atccgggaggcgttgcagcagggcgtcatcactgcgcagagttccgacgtcctcagcggc
ggagtggcgttggtcggcggcggtcccggcgatcccgaactgatcacggttcgcggtcgc
cggctgcttgcccaggccgatgtcgtggtcgccgaccggctcgccccgcccgaactgctg
gccgagctgccgccgcacgtagaagtcatcgacgcggccaagatcccttacggccgggcc
atggcccaggacgcgatcaacgctgtcctgatcgaacgggccagatccggcaactttgtg
gtccgtctcaaagggggcgaccccttcgtgttcgcccggggctatgaagaagtgctggca
tgtgcccacgccggaatcccggtcaccgtggtgccaggtgtgacgagtgccatagccgtg
cccgctatggcgggcgttccagtcactcaccgggccatgacccacgaattcgtggtggtc
agtggccatcttgcgcccggtcatcccgaatcgttagtgaattgggatgcattggctgca
ttgacgggcaccatcgttttgctgatggcggtcgaacgcatcgagcttttcgttgacgtt
ctgctaaagggtggccgaactgcggatacgccggtactggtggttcaacacggaacgacc
gccgctcaacagacgttgcgggccacccttgccgacacgccggagaaggtccgcgcggcg
gggatccgacctcccgcgatcatcgtgatcggggctgtagtcggcctgagcggcgttcgg
ggtttaaacaattcttaa

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