KEGG M.tuberculosis: Rv0957

Mycobacterium tuberculosis H37Rv: Rv0957

Entry

Rv0957 CDS M.tuberculosis

Gene name purH

Definition bifunctional phosphoribosylaminoimidazolecarboxamide
formyltransferase/IMP cyclohydrolase (EC:3.5.4.10 2.1.2.3)

Orthology K00602 phosphoribosylaminoimidazolecarboxamide formyltransferase /
IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]

Pathway mtu00230 Purine metabolism
mtu00670 One carbon pool by folate
mtu01100 Metabolic pathways

Class Metabolism; Nucleotide Metabolism; Purine metabolism [PATH:mtu00230]
Metabolism; Metabolism of Cofactors and Vitamins; One carbon pool by
folate [PATH:mtu00670]

SSDB

Motif Pfam: AICARFT_IMPCHas MGS PIG-L

Other DBs NCBI-GI: 15608097
NCBI-GeneID: 885406
Sanger: Rv0957
Pasteur: Rv0957
UniProt: P67541

Position 1068205..1069776

AA seq 523 aa
MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQL
TGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESG
ASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASL
AFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPT
AWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADA
HRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRV
LVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRA
CRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLE
TLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH

NT seq 1572 nt +upstreamnt +downstreamnt
atgagcaccgacgacggaagacggccgatccgccgtgcgctgatcagcgtgtacgacaag
accgggctggtagacctggcacagggcctgagcgcggccggcgtcgagatcatctcgact
gggtcaacggccaagaccattgccgacaccgggattccggtgacccccgtggagcagctg
accggctttcccgaggtgctcgatggccgggtcaagacactgcacccacgagtgcatgcc
gggctgctggctgacctgcgcaagtccgagcacgccgcggccctcgagcaactcgggatc
gaggctttcgaactcgttgtagtcaacttgtatccgttcagccagaccgtcgaatccggc
gccagtgtcgacgactgcgtcgagcagattgatatcggcgggccggcgatggtgcgggcc
gccgccaaaaaccatcccagcgcggcggtggtcaccgatccgcttgggtaccatggcgtg
cttgccgcactgcgcgccggcggattcaccctcgccgagcgcaaaaggctggcgtcgtta
gcgtttcagcatatagccgagtacgacatcgccgtcgcgagctggatgcaacagacccta
gcgcccgaacatcctgttgccgcctttccgcagtggttcggccgaagctggcgccgcgtg
gcgatgctgcgctacggcgagaacccgcaccaacaggccgctctctacggcgaccccacc
gcctggccggggctggcccaggccgagcaactgcacggaaaagacatgtcctacaacaac
ttcaccgatgcggacgcagcctggcgggccgccttcgaccacgaacaaacgtgcgtggcg
atcatcaagcacgccaacccgtgcggcatcgcaatctcgtccgtttcggtcgccgacgcg
catcgcaaggctcacgaatgcgatccgctgagcgcctacggcggggtcatcgccgccaat
accgaggtcagtgtcgaaatggccgagtatgtgagcaccatcttcaccgaagtcatcgtc
gcgcctggctacgcccccggggccctcgatgtgctggcccgcaagaagaacatccgggtg
ctggtagccgccgagccactggccggtggcagcgagttgcgtccgatcagcggtggactg
ctgatacagcagagcgaccagcttgacgcgcacggtgacaacccggcgaactggaccttg
gcgaccgggtcacctgcggaccccgcgacgctgaccgacctggtcttcgcgtggcgagcc
tgccgtgcggtcaagtcgaacgcgatagtgatagctgccgacggcgccaccgtcggcgtc
gggatgggtcaggtcaaccgtgtcgacgccgcccggttggccgtcgaacgcggcggcgag
cgggttcgcggcgcggtggcagcctcggatgcgttcttcccctttcccgacggcctggaa
acgttggccgccgcgggggtcaccgcggtcgtccaccccggtggctcggtgcgcgacgag
gaagtgaccgaagcggcggccaaggccggtgtcaccctatatctcaccggggcgcggcac
ttcgcgcactga

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (2)   
   KEGG ENZYME (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (2)   
   PASTEUR-MTU (1)   
   SANGER-MTU (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (4)   
   GenBank (2)   
   EMBL (2)   
Protein domain (3)   
   Pfam (3)   
All databases (21)

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