KEGG T00015: Rv2763c

Mycobacterium tuberculosis H37Rv: Rv2763c

Entry

Rv2763c CDS T00015

Gene name

dfrA

Definition

Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase)

Orthology

K00287

dihydrofolate reductase [EC:1.5.1.3]

Organism

mtu Mycobacterium tuberculosis H37Rv

Pathway

mtu00670	One carbon pool by folate
mtu00790	Folate biosynthesis
mtu01100	Metabolic pathways

Class

Metabolism; Metabolism of cofactors and vitamins; Folate biosynthesis [PATH:mtu00790]
Metabolism; Metabolism of cofactors and vitamins; One carbon pool by folate [PATH:mtu00670]

SSDB

Motif

Pfam:

DHFR_1

Other DBs

NCBI-GI:

NCBI-GeneID:

TubercuList:

UniProt:

Structure

PDB:

1DF7 1DG7 1DG5 1DG8 2CIG

Position

complement(3073130..3073609)

AA seq 159 aa
MVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLPGR
RNVVLSRQADFMASGAEVVGSLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIGLP
REAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS

NT seq 480 nt +upstreamnt +downstreamnt
atggtggggctgatctgggctcaagcgacatcgggtgtcatcggccgcggcggcgacatc
ccctggcgcttgcccgaggaccaggcgcatttccgggagatcaccatggggcacacgatc
gtgatgggccggcgcacatgggattcgctgccggctaaagtccggccgctgcccggccgg
cgaaatgtcgtactgagccgccaagctgactttatggccagcggggctgaggttgtcggt
tcactcgaggaggcgctgaccagcccggagacgtgggtgatcggaggcggacaagtctat
gcgctggcgctgccgtacgcgaccagatgtgaggttaccgaggtcgacatcggcctgccg
cgcgaagccggtgacgcgctggcccccgtgctggacgagacatggcggggcgagacgggg
gagtggcgcttcagccggtccgggttgcggtaccggttgtacagctaccaccgctcatga

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (7)   
   KEGG ENZYME (1)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
   TUBERCULIST (1)   
Protein sequence (3)   
   UniProt (2)   
   RefSeq(pep) (1)   
3D Structure (5)   
   PDB (5)   
Protein domain (1)   
   Pfam (1)   
All databases (33)   

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