KEGG T00015: Rv3708c

Mycobacterium tuberculosis H37Rv: Rv3708c

Entry

Rv3708c CDS T00015

Gene name

asd

Definition

Aspartate-semialdehyde dehydrogenase Asd (ASA dehydrogenase) (ASADH) (aspartic semialdehyde dehydrogenase) (L-aspartate-beta-semialdehyde dehydrogenase)

Orthology

K00133

aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]

Organism

mtu Mycobacterium tuberculosis H37Rv

Pathway

mtu00260	Glycine, serine and threonine metabolism
mtu00270	Cysteine and methionine metabolism
mtu00300	Lysine biosynthesis
mtu01100	Metabolic pathways
mtu01110	Biosynthesis of secondary metabolites
mtu01120	Microbial metabolism in diverse environments
mtu01210	2-Oxocarboxylic acid metabolism
mtu01230	Biosynthesis of amino acids

Module

mtu_M00016	Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
mtu_M00018	Threonine biosynthesis, aspartate => homoserine => threonine

Class

Metabolism; Amino acid metabolism; Glycine, serine and threonine metabolism [PATH:mtu00260]
Metabolism; Amino acid metabolism; Cysteine and methionine metabolism [PATH:mtu00270]
Metabolism; Amino acid metabolism; Lysine biosynthesis [PATH:mtu00300]

SSDB

Motif

Pfam:

Semialdhyde_dhC Semialdhyde_dh

Other DBs

NCBI-GI:

NCBI-GeneID:

TubercuList:

UniProt:

Structure

PDB:

3TZ6 3VOS 3LLG

Position

complement(4151180..4152217)

AA seq 345 aa
MGLSIGIVGATGQVGQVMRTLLDERDFPASAVRFFASARSQGRKLAFRGQEIEVEDAETA
DPSGLDIALFSAGSAMSKVQAPRFAAAGVTVIDNSSAWRKDPDVPLVVSEVNFERDAHRR
PKGIIANPNCTTMAAMPVLKVLHDEARLVRLVVSSYQAVSGSGLAGVAELAEQARAVIGG
AEQLVYDGGALEFPPPNTYVAPIAFNVVPLAGSLVDDGSGETDEDQKLRFESRKILGIPD
LLVSGTCVRVPVFTGHSLSINAEFAQPLSPERARELLDGATGVQLVDVPTPLAAAGVDES
LVGRIRRDPGVPDGRGLALFVSGDNLRKGAALNTIQIAELLTADL

NT seq 1038 nt +upstreamnt +downstreamnt
atgggcctgtcaatagggatcgtgggggccaccggtcaggtgggtcaggtcatgcgcacg
ttgctcgacgagcgggatttcccggcgagcgcggtgcggttcttcgcgtcggcccgatcg
cagggccgcaagctggccttccgcggccaggagatcgaagtggaagacgccgagacggcc
gacccgagcgggctggatatcgcgttgttctccgccggctcggccatgtcgaaggtgcag
gcgccccgctttgcggcggccggagtcacggtgatcgacaactcgtcggcgtggcgtaag
gaccccgacgtgccgttggtggtgtccgaggtgaactttgaacgcgacgcgcaccgccgg
cctaagggcatcatcgccaacccgaactgcaccaccatggccgcgatgccggtgctcaag
gtgctgcacgacgaagcccgactggtgcggttggtggtctcgtcgtatcaggcggtgtcc
ggtagcggcctggccggggtggccgagctggccgagcaggcgcgtgcggtcatcggtggg
gccgagcagctggtgtatgacggcggcgcgctcgagttcccgccgccgaacacctacgtc
gccccgatcgcgttcaacgtggtgccgctggccggatccctggtggacgacggctccggc
gagacagacgaggatcaaaagttgcgcttcgagagccgcaagatccttggcatccccgac
ctgttggtcagcggcacctgtgtgcgggttccggtgttcaccggacactctttgtcgatc
aacgccgagttcgcgcagccgctctcgccggagcgggcgcgcgagctgctcgacggtgct
acgggcgtgcagctggtcgacgtgccgacgccgctggccgccgccggtgtcgacgaatct
ctggtcggccggatccggcgcgacccgggggtgcccgacgggcgtggtctggcgctgttc
gtgtcgggggataacctgcgcaagggggcggcgctgaacaccatccagatcgccgagctg
ctgaccgccgacttgtga

All links

Pathway (10)   
   KEGG PATHWAY (8)   
   KEGG MODULE (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
   TUBERCULIST (1)   
Protein sequence (3)   
   UniProt (2)   
   RefSeq(pep) (1)   
3D Structure (3)   
   PDB (3)   
Protein domain (2)   
   Pfam (2)   
All databases (32)   

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