KEGG   Mycobacterium tuberculosis 7199-99: MT7199_0524
Entry
MT7199_0524       CDS       T02617                                 
Name
(GenBank) putative PORPHOBILINOGEN DEAMINASE HEMC (PBG) (HYDROXYMETHYLBILANE SYNTHASE) (HMBS) (PRE-UROPORPHYRINOGEN SYNTHASE)
  KO
K01749  hydroxymethylbilane synthase [EC:2.5.1.61]
Organism
mtub  Mycobacterium tuberculosis 7199-99
Pathway
mtub00860  Porphyrin metabolism
mtub01100  Metabolic pathways
mtub01110  Biosynthesis of secondary metabolites
mtub01120  Microbial metabolism in diverse environments
mtub01240  Biosynthesis of cofactors
Module
mtub_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
mtub_M00926  Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:mtub00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    MT7199_0524
Enzymes [BR:mtub01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.61  hydroxymethylbilane synthase
     MT7199_0524
SSDB
Motif
Pfam: Porphobil_deam Porphobil_deamC FrhB_FdhB_N
Other DBs
NCBI-ProteinID: CCG10373
Position
605978..606907
AA seq 309 aa
MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALRE
AMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTS
SPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLE
PVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGA
IAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGA
RELMWGVRP
NT seq 930 nt   +upstreamnt  +downstreamnt
gtgatccggataggtacccggggcagcttgctggccaccactcaggccgccactgtcaga
gacgccctcatcgctggtggccactccgcggagttggtgaccatcagcaccgagggtgac
cgatccatggcgccgatcgccagtctcggggttggcgtcttcaccacggcgttgcgcgag
gcgatggaggcaggcctcgtcgatgcggcggtgcattcgtacaaggatttgccgactgcc
gccgatccaaggttcacggttgcggcgataccgccgcgcaatgacccccgcgacgcggtg
gtagcccgtgacgggctgacgctgggggaattgccggtcggatcgttggtgggcacatcc
tcgccgcggcgggccgcacagcttagagcattgggtctcggtttggaaatccgcccccta
cgaggcaacctagataccaggttgaacaaggtaagtagcggcgatcttgacgccatcgtg
gtggcccgggctggtctggcgcggctgggccgcctcgatgacgtgaccgagacgttagag
ccggtgcagatgttgcccgcgccggctcagggcgcgctcgcggtcgaatgccgcgccggc
gacagccggttggtggcagtgctggcggagttggatgacgccgacacgcgtgcggcggtc
accgccgagcgagccctgcttgccgacctggaggcaggttgctccgcaccggtgggagcg
atcgcagaagtggtcgagtccatcgatgaggacggccgtgtcttcgaggagctgtcgctg
cgcgggtgcgtggcggcgctggacggatccgacgtgatccgcgcgtccggcatcggcagt
tgcggtcgggcacgggagctggggctctcggtcgccgcggagctgttcgagctgggcgcc
cgggagctgatgtggggagtgcggccttag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (9)   
   KEGG PATHWAY (5)   
   KEGG MODULE (4)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (3)   
   Pfam (3)   
All databases (24)   

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