KEGG T03153: HKBT2

Mycobacterium tuberculosis BT2: HKBT2_3609

Entry

HKBT2_3609        CDS       T03153

Symbol

guaB2

Name

(GenBank) inosine 5'-monophosphate dehydrogenase

K00088

IMP dehydrogenase [EC:1.1.1.205]

Organism

mtuu Mycobacterium tuberculosis BT2

Pathway

mtuu00230

Purine metabolism

mtuu00983

Drug metabolism - other enzymes

mtuu01100

Metabolic pathways

mtuu01110

Biosynthesis of secondary metabolites

mtuu01232

Nucleotide metabolism

Module

mtuu_M00050

Guanine ribonucleotide biosynthesis, IMP => GDP,GTP

Brite

KEGG Orthology (KO) [BR:mtuu00001]
09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    HKBT2_3609 (guaB2)
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    HKBT2_3609 (guaB2)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mtuu04147]
    HKBT2_3609 (guaB2)
Enzymes [BR:mtuu01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.205  IMP dehydrogenase
     HKBT2_3609 (guaB2)
Exosome [BR:mtuu04147]
Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   HKBT2_3609 (guaB2)
  Exosomal proteins of breast cancer cells
   HKBT2_3609 (guaB2)

SSDB

Motif

Pfam:

IMPDH CBS NMO FMN_dh His_biosynth Glu_synthase

Other DBs

NCBI-ProteinID:

AHJ48406

Position

complement(3816849..3818438)

AA seq 529 aa
MSRGMSGLEDSSDLVVSPYVRMGGLTTDPVPTGGDDPHKVAMLGLTFDDVLLLPAASDVV
PATADTSSQLTKKIRLKVPLVSSAMDTVTESRMAIAMARAGGMGVLHRNLPVAEQAGQVE
MVKRSEAGMVTDPVTCRPDNTLAQVDALCARFRISGLPVVDDDGALVGIITNRDMRFEVD
QSKQVAEVMTKAPLITAQEGVSASAALGLLRRNKIEKLPVVDGRGRLTGLITVKDFVKTE
QHPLATKDSDGRLLVGAAVGVGGDAWVRAMMLVDAGVDVLVVDTAHAHNRLVLDMVGKLK
SEVGDRVEVVGGNVATRSAAAALVDAGADAVKVGVGPGSICTTRVVAGVGAPQITAILEA
VAACRPAGVPVIADGGLQYSGDIAKALAAGTSTAMLGSLLAGTAEAPGELIFVNGKQYKS
YRGMGSLGAMRGRGGATSYSKDRYFADDALSEDKLVPEGIEGRVPFRGPLSSVIHQLTGG
LRAAMGYTGSPTIEVLQQAQFVRITPAGLKESHPHDVAMTVEAPNYYAR

NT seq 1590 nt +upstreamnt +downstreamnt
atgtcccgtggcatgtccggcctggaagacagctccgacctggtggtcagcccgtacgtt
cgcatgggcggcctgactactgacccggtgcccaccggcggcgacgacccgcacaaggtg
gcgatgctggggctgacattcgacgacgtcttgttgttgccggcggcttccgacgtggtg
cccgccaccgcggatacctccagccagctcaccaagaagatcaggctcaaggtgccactg
gtcagctcggcgatggacaccgtcaccgagtcgcgtatggccatcgcgatggcacgggcg
ggtggcatgggggtgttgcaccgcaacctgcccgttgccgagcaagccggccaggtcgag
atggtgaagcgatccgaggccggcatggtcaccgatcccgtcacctgccggccggacaac
accttggcccaggtcgatgcgctgtgcgcccggttccggatctccgggttgccggtggtc
gacgacgacggtgcgctggtgggcatcatcaccaaccgtgacatgcggtttgaggtcgac
cagtccaagcaggtcgccgaggtgatgaccaaagccccgctgatcaccgctcaagagggt
gtcagtgcgtccgcggcgctgggcctgttgcgccgcaacaagatcgagaagctgcccgtg
gtcgacggccgcggccggctgaccgggctgatcaccgtcaaggacttcgtcaagaccgag
caacacccgctggccaccaaggacagcgacggccggctgctggtgggggcggccgtcggc
gtcggcggcgatgcctgggtgcgcgccatgatgttggtcgacgccggggtcgacgtgctg
gtcgtggacaccgcgcacgcgcacaaccggttggtgctcgacatggtgggcaaactcaag
tccgaagtcggcgaccgggttgaggtggtaggcggcaacgtcgccaccaggtccgcggcc
gcggccctggtcgacgccggagccgacgcggtgaaagtcggcgtggggccggggtcgatc
tgcacgacgagggtggtggccggggtgggcgcgccgcagatcacggcgatcttggaagct
gtagcggcttgtcgtcctgctggcgtgccggtgatcgccgacggcggactgcagtactcc
ggcgacatcgccaaggcgctggccgccggtacgtcgacggccatgctgggctcgctgctg
gccggcacagccgaggcgcccggtgagctgatcttcgtgaacggcaagcagtacaagagt
tatcgcggcatgggatcactgggtgccatgcgagggcgtgggggggcgacgtcgtattcc
aaggatcgctacttcgccgacgacgcgctgtcggaagacaaactggtgccggaagggatc
gaggggcgggtgccgttccgtggtccgctgtcgtcggtgatccaccagttgaccggtggc
ctgcgcgccgcgatgggctacaccgggtcgcccaccatcgaggtgctacagcaggcgcaa
ttcgtccggatcacacccgcgggcctcaaggagagtcatccccacgacgtcgcgatgacc
gtcgaggcgcccaactactacgcgcgctaa

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