KEGG   Mycobacterium ulcerans: MUL_4600Help
Entry
MUL_4600          CDS       T00435                                 

Gene name
hemD
Definition
uroporphyrin-III C-methyltransferase HemD
Orthology
K13542  
uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
Organism
mul  Mycobacterium ulcerans
Pathway
Porphyrin and chlorophyll metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Module
Heme biosynthesis, glutamate => protoheme/siroheme
Brite
KEGG Orthology (KO) [BR:mul00001]
 Metabolism
  Metabolism of cofactors and vitamins
   00860 Porphyrin and chlorophyll metabolism
    MUL_4600 (hemD)
Enzymes [BR:mul01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     MUL_4600 (hemD)
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.75  uroporphyrinogen-III synthase
     MUL_4600 (hemD)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Pasteur: 
UniProt: 
Position
5100701..5102374
Genome map
AA seq 557 aa AA seqDB search
MTRGRKPRPGRITYVGSGPGDPGLLTTRAAAVLANAALVFTDPDVPESVLALIGNDLPPV
SGPAPATAVADNADAATGGPAEGESDQAVPAVVSSGPDIRPALGDPTEVAKTLTAEARSG
ADVVRLVAGDPMSVDAVIAEVNAITRSHLQIEILPGLAATSAVPTYAGLPLGSAHTVADV
RGDVDWEALAAAPGPLILQATASHLADAARTLVEHELADTTPCVVTAHGTTCQQRSVETT
LQGLTDPAILGGTDPAGPLTGPLVVTIGKTVSNRAKLNWWESRALYGWTVLVPRTKDQAG
EMSERLTSYGALPVEVPTIAVAPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKF
GEFGLDARAFSGVKIACVGESTADRVRAFGISPELVPAGEQSSLGLLDEFPPYDSIFDPV
NRVLLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAATREMIKTGGFDAVCFTS
SSTVRNLVGIAGKPHARTIIACIGPKTAETAAEFGLRVDVQPETAAVGPLVDALAEHAAR
LRAEGALPPPRKKSRRR
NT seq 1674 nt NT seq  +upstreamnt  +downstreamnt
atgacgcgagggcgcaagccgaggccgggccgcattacttatgtgggctctggcccaggt
gacccgggtctgttgaccacacgggccgccgcggtactggcgaacgccgccctggtgttc
acggaccccgatgtgcctgagtcggtgctggccctgatcggtaacgatctgccgcccgtc
tccgggccggcgcccgcgactgcagtggccgacaatgctgacgctgcgaccggcggcccc
gccgagggcgagtccgaccaggcggttccggcggtggtctctagtggtccggacatccgc
ccggcgctgggtgatcccaccgaagttgccaaaacgctgaccgccgaagcccgttcgggc
gccgacgtggtgcgtttggtggccggtgacccgatgtcggtggacgcggtgatcgccgag
gtcaacgccattacccgcagccacctgcagatcgagatcctgcccggtctggcggcaacc
agcgcggtcccgacctatgcgggactgcccctgggctccgcgcacacggttgccgacgtg
cgtggcgacgtggactgggaggcgctggccgccgcaccgggtccgctgatcctgcaggcc
accgcgtcacatctggctgacgcggcccgcacgctggttgagcacgagctggcggacaca
acgccgtgcgtggtgaccgcgcacggaaccacctgccaacagcgctcggtggaaaccacc
ctgcaggggctgaccgatccggccatcctgggtggaaccgaccctgccggcccgctgacc
gggccgctggtggtgaccatcggcaagaccgtgagcaatcgcgccaagctgaactggtgg
gagagccgggcactgtacggctggaccgtattggtaccccgaaccaaagaccaggccggc
gaaatgagcgagcggctgacgtcctacggtgccctgccggtcgaggtgccgacgatcgcc
gtcgcaccgccgcgcagcccggcgcagatggaacgcgcggtcaaaggcctggtcgacggc
cggttccaatgggtcgtgttcacctccaccaacgccgtgcgcgcggtgtgggagaagttc
ggcgagttcggcctggatgcccgggcgttctccggagtgaagatcgcctgtgtgggcgag
tcgactgccgaccgggttcgcgctttcgggatcagcccggagctggtcccggccggggaa
cagtcctcgctgggcctgctggacgaattcccgccctacgacagcattttcgatccggtc
aaccgggtgttgctgccgcgcgctgacatcgccaccgagacgctggccgaggggctgcgc
gagcgtggctgggagatcgaggacgtgacggcctaccgcacggtgcgggccgctccgccg
ccggcggccacccgcgagatgatcaagacgggcggtttcgacgcggtctgcttcacctcg
agttctacggtgcgcaatctggtcggtatcgccggtaagccgcacgcgcggaccatcatc
gcctgcatcggacccaagaccgccgaaacggccgccgagttcgggctccgggtggatgtc
caacccgagactgccgcggtgggtccgctggtggacgcgctggccgagcacgccgcccgg
ctgcgcgccgaaggagccctgcccccgcctcgcaagaagagtcgccggcgctag

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