KEGG   Myotis brandtii (Brandt's bat): 102252005Help
Entry
102252005         CDS       T02920                                 

Gene name
INSR
Definition
(RefSeq) insulin receptor
  KO
K04527  
insulin receptor [EC:2.7.10.1]
Organism
myb  Myotis brandtii (Brandt's bat)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phospholipase D signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adherens junction
Insulin signaling pathway
Ovarian steroidogenesis
Regulation of lipolysis in adipocytes
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:myb00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    102252005 (INSR)
   04015 Rap1 signaling pathway
    102252005 (INSR)
   04010 MAPK signaling pathway
    102252005 (INSR)
   04066 HIF-1 signaling pathway
    102252005 (INSR)
   04068 FoxO signaling pathway
    102252005 (INSR)
   04072 Phospholipase D signaling pathway
    102252005 (INSR)
   04022 cGMP - PKG signaling pathway
    102252005 (INSR)
   04151 PI3K-Akt signaling pathway
    102252005 (INSR)
   04152 AMPK signaling pathway
    102252005 (INSR)
   04150 mTOR signaling pathway
    102252005 (INSR)
 Cellular Processes
  Cellular community - eukaryotes
   04520 Adherens junction
    102252005 (INSR)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    102252005 (INSR)
   04923 Regulation of lipolysis in adipocyte
    102252005 (INSR)
   04913 Ovarian Steroidogenesis
    102252005 (INSR)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102252005 (INSR)
  Aging
   04211 Longevity regulating pathway - mammal
    102252005 (INSR)
   04213 Longevity regulating pathway - multiple species
    102252005 (INSR)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    102252005 (INSR)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    102252005 (INSR)
   04931 Insulin resistance
    102252005 (INSR)
Enzymes [BR:myb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     102252005 (INSR)
Protein kinases [BR:myb01001]
 Tyrosine protein kinases
  InsR family [OT]
   102252005 (INSR)
Enzyme-linked receptors [BR:myb01020]
 Receptor tyrosine kinases
  RTK class II (Insulin receptor family)
   102252005 (INSR)
Cytokine receptors [BR:myb04050]
 Receptor tyrosine kinase
  RTK class II (Insulin receptor family)
   102252005 (INSR)
CD molecules [BR:myb04090]
 Proteins
  102252005 (INSR)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Position
Un
AA seq 1384 aa AA seqDB search
MYGRGFSQGQDPLSNALPPILKTHHCVLAHLSHFLHIFTLVCPSMDIRNNFTRLYELANC
SIIEGHLQILLMFSSRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSR
LFFNYALVIFEMVHLKELGLYSLMNITRGSVRIEKNNDLCYLATIDWSRILDSVEDNYIV
LNKDDNEECGDVCPGTAKGKTSCPATVINGQFVERCWTHSHCQKVCPTSCKSHGCTAEGL
CCHPECLGSCSEPDDPTKCVACRHFYLDGRCVETCPAPYYHFRDWRCVNFSFCLDLHNKC
KNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHVLEGQKIIDSVTA
AQELRGCTVINGSLTINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLR
LIQGDTLEVGNYSFYALDNQNLRQLWDWSKHNLTITRGKLFFHYNPKLCLSEIHKMEEIS
GTKGRQERTDIALKTNGDQASCENELLKFSYIRTSSDKIMLKWEPYWPPDFRDLLGFMLF
YKEAPYRNVTEFDGQDACGSNSWTVVDIDPPPRSTDPKSQAHPGWLMRSLKPWTQYAIFV
KTLVTFSDERRTYGAKSDIIYIQTNATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNIT
HYLVFWERQEEDSELYELDYCLKGLKLPSRTWSPPSELEGSQKHNQSEYDEAAGECCSCP
KTDSQILKELEESSFRKTFENYLHNVVFVPRKISSGPGAEDSRSSRKRRALGDEGNVTTA
EPTALGFPNTSTIVPTRSEEPRPFEKVVNKESLVISGLRHFTGYRIELQACNQDFPEERC
SVAAYISARTMPEAKADDIVGPVTHEIFENNIVHLMWQEPKHPNGLIVLYEVSYRRYGDE
ELHLCVSRRHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEATYFYVTNYLDVPSNI
AKIIIGPLIFVFLFSVVIGSIYLFLRKRQSDGPVGPLYASSNPEYLSASDVFPCSVYVPD
EWEVPREKITLLRELGQGSFGMVYEGNAKDIIKGEAETRVAVKTVNESASMRERIEFLNE
ASVMKGFACHHVVRLLGVVSKGQPTLVVMELMTHGDLKSHLRSLRPDAENNPGRPPPTLQ
EMFQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGG
KGLLPVRWMAPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGY
LDIPDNCPERLSELMSMCWHFNPKMRPTFLEVVDLLKDNLHPSFPEVSFFYSEENKAPEN
DELEMEFEDMESVPLDRSSHCQREEDGGCPLALKRNYEDHMSYSHMNGGKKNGRVLTLPR
SSPS
NT seq 4155 nt NT seq  +upstreamnt  +downstreamnt
atgtatggaaggggatttagccaagggcaggaccctctgagcaatgccctgccgccaatt
cttaaaacccaccattgtgtgttagctcacctgtcacactttctgcatatttttactcta
gtgtgtcccagcatggatatccggaacaacttcacgaggctgtatgagctggctaactgc
tcgatcatcgaaggacatttgcagatactgttgatgttcagttcaaggcctgaggatttc
cgagacctcagtttccccaaactcatcatgatcactgattacttgctgctgtttcgggtc
tatgggctggagagcctgaaggacctgttccccaacctcacggtcatccggggctcccgc
ctcttcttcaactacgcgctggtcatcttcgagatggtccacctgaaggagctgggcctc
tacagcctgatgaacatcacccgggggtctgtccgcatcgagaagaacaatgatctctgc
tacctggctaccatcgactggtcgcgcatcctggactcggtggaggataattacatcgtg
ctgaacaaagacgacaatgaagagtgtggggacgtctgtccgggcactgcgaagggcaag
accagctgccctgccactgtcatcaatgggcagtttgtcgaacggtgttggactcacagc
cattgccagaaagtctgcccgaccagctgcaagtcgcacggctgcactgctgaaggcctc
tgctgccaccccgagtgcctgggcagctgctctgagcccgacgaccccaccaagtgcgtg
gcctgccgccacttctacctggacggtaggtgcgtggagacctgcccagccccgtactac
cacttccgggactggcgctgtgtgaacttcagcttctgcctggacctgcacaacaaatgc
aagaactcgcggaggcagggctgccatcagtacgtcattcacaacaacaagtgcattcct
gagtgcccctctgggtacacgatgaattccagcaacttgatgtgcactccgtgtctgggc
ccctgtcccaaggtctgccacgtcctggaaggtcagaagatcatcgactcagtgacagct
gcccaggagcttcgaggatgcaccgtcatcaacgggagcctcaccatcaacatccgtggg
ggcaacaacctggcagctgagcttgaggccaacctcggcctcattgaggaaatttcaggg
tatctgaaaatccgccgttcctacgctctagtgtcactttccttcttccggaagttacgt
ctgattcagggggataccttggaagttgggaactactctttctatgccttggacaaccag
aacctaaggcagctatgggactggagcaaacacaacctcaccataactcgggggaaactc
ttcttccactataatcccaaactctgcttgtcggaaattcacaagatggaagaaatttca
ggaaccaagggacgccaggagaggaccgacattgccctgaagactaatggggaccaggcg
tcctgtgaaaatgaattacttaaattttcttacatccggacatcttctgacaagatcatg
ctgaaatgggagccgtactggccccctgacttccgagacctcctggggttcatgctcttc
tacaaagaggccccttaccggaatgtgacggagtttgatgggcaggatgcgtgtggatcc
aacagctggacggtggtggacattgacccgcctccgaggtccactgaccccaagtcacag
gcccatcctgggtggctgatgcggagtctcaagccctggactcagtatgccatcttcgtg
aagaccttggtcaccttttctgatgaacgccgcacatacggggccaagagcgatatcatc
tatatccagacaaatgccaccaatccttccgtccccttggatcccatctcggtttctaac
tcttcatcccagattatcttgaagtggaagcctccctccgaccccaacggcaacatcaca
cactacctggttttctgggagaggcaggaggaagacagtgagctgtatgagctggattat
tgcctcaaagggttgaagctgccctcccggacctggtccccaccatctgagttggagggt
tcccagaagcacaaccagagcgagtacgacgaggctgccggcgagtgctgctcctgcccg
aagactgactctcagattctgaaggaactggaggagtcctcgttcaggaagacgtttgag
aattacctgcacaatgtggtcttcgtccccagaaaaatctcttcaggccctggtgctgag
gacagtaggtcgtcgagaaaacgcagggcccttggtgatgaagggaacgtgacgacggct
gagcccacagctctgggtttccccaacacctcaaccatcgtgcccacacgctcggaggag
ccgcggcccttcgagaaagtggtgaacaaggagtcgctggtcatctcgggcctgcgccac
ttcactggctaccgcatcgagctgcaggcttgcaaccaggatttccccgaggagaggtgc
agtgtggcggcctacatcagcgccaggaccatgcccgaagccaaggcagatgacattgtt
ggccccgtgacccatgaaatcttcgagaacaacatcgttcatttgatgtggcaggagcca
aagcatccgaacggtctgattgtgctgtatgaagtgagctatcgacgatacggagatgag
gagctgcacctctgtgtgtcccgcaggcacttcgccttggagcggggctgcaggctacgc
gggctgtcgcccgggaattacagcgtgagagtccgggccacctccctggcgggcaatggt
tcctggacagaagccacctatttctatgtgacaaactacttagacgtcccctccaatatt
gcaaaaatcatcatcggccccctcatctttgtcttcctcttcagtgttgtgattggaagt
atttacctattcctgaggaagaggcagtcagacgggccggtgggaccactctatgcttct
tcaaaccctgagtacctcagtgccagcgatgtgttcccatgttctgtgtatgtgccggac
gagtgggaggtgcctcgggagaagatcacgctcctgcgagagctggggcagggctccttc
ggcatggtgtacgagggcaacgccaaggacatcatcaagggcgaggcagagactcgagtg
gcggtgaagacagtcaacgagtcggccagcatgcgggagcggatcgagtttctcaacgag
gcctccgtcatgaaaggcttcgcctgccatcacgtggtgcgcctcctcggggtggtgtcc
aaaggccagcccacactggtggtgatggagctcatgactcacggagacctgaagagccac
ctgcgttccctgcggcctgacgccgagaataaccccggccgccctcccccgaccctgcaa
gagatgtttcagatggcagcggagattgctgacgggatggcatacctgaacgccaagaag
tttgtgcaccgggacctcgcagctcgaaactgcatggtcgcccacgattttaccgtcaaa
attggagactttggaatgaccagagacatctacgaaacggattattaccggaaaggtggc
aaaggtctgcttcctgtgaggtggatggcacctgaatctttgaaggacggggtctttact
gcttcttccgacatgtggtccttcggtgtggtcctgtgggaaatcaccagcttggcagaa
cagccttaccaaggcctctccaatgagcaggtgctgaaattcgttatggatggagggtat
ctggatatccctgacaattgtccagagagactcagtgaattgatgagcatgtgctggcat
ttcaatcccaagatgaggccgaccttcctggaggtcgttgacctgctgaaggacaacctg
caccccagctttccggaagtttccttcttctacagcgaggagaacaaggcacctgagaac
gatgagttggagatggagtttgaggacatggagagtgtacccctggaccggtcctcacac
tgtcagagggaggaggatggggggtgtccgctggccctaaagcggaattacgaggatcac
atgtcctacagccacatgaatgggggcaagaaaaacggacgtgtcctgactctgccacgg
tccagtccttcctaa

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