KEGG   Myotis brandtii (Brandt's bat): 102252921Help
Entry
102252921         CDS       T02920                                 

Gene name
PIK3CD
Definition
(RefSeq) phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
  KO
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
myb  Myotis brandtii (Brandt's bat)
Pathway
Inositol phosphate metabolism
EGFR tyrosine kinase inhibitor resistance
Endocrine resistance
Platinum drug resistance
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
Sphingolipid signaling pathway
Phospholipase D signaling pathway
Autophagy - animal
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Longevity regulating pathway
Longevity regulating pathway - multiple species
Cellular senescence
Axon guidance
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Signaling pathways regulating pluripotency of stem cells
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Regulation of lipolysis in adipocytes
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
AGE-RAGE signaling pathway in diabetic complications
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Kaposi's sarcoma-associated herpesvirus infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Breast cancer
Central carbon metabolism in cancer
Choline metabolism in cancer
Fluid shear stress and atherosclerosis
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:myb00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102252921 (PIK3CD)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    102252921 (PIK3CD)
   04015 Rap1 signaling pathway
    102252921 (PIK3CD)
   04012 ErbB signaling pathway
    102252921 (PIK3CD)
   04370 VEGF signaling pathway
    102252921 (PIK3CD)
   04630 Jak-STAT signaling pathway
    102252921 (PIK3CD)
   04668 TNF signaling pathway
    102252921 (PIK3CD)
   04066 HIF-1 signaling pathway
    102252921 (PIK3CD)
   04068 FoxO signaling pathway
    102252921 (PIK3CD)
   04070 Phosphatidylinositol signaling system
    102252921 (PIK3CD)
   04072 Phospholipase D signaling pathway
    102252921 (PIK3CD)
   04071 Sphingolipid signaling pathway
    102252921 (PIK3CD)
   04024 cAMP signaling pathway
    102252921 (PIK3CD)
   04151 PI3K-Akt signaling pathway
    102252921 (PIK3CD)
   04152 AMPK signaling pathway
    102252921 (PIK3CD)
   04150 mTOR signaling pathway
    102252921 (PIK3CD)
 Cellular Processes
  Transport and catabolism
   04140 Autophagy - animal
    102252921 (PIK3CD)
  Cell growth and death
   04210 Apoptosis
    102252921 (PIK3CD)
   04218 Cellular senescence
    102252921 (PIK3CD)
  Cellular community - eukaryotes
   04510 Focal adhesion
    102252921 (PIK3CD)
   04550 Signaling pathways regulating pluripotency of stem cells
    102252921 (PIK3CD)
  Cell motility
   04810 Regulation of actin cytoskeleton
    102252921 (PIK3CD)
 Organismal Systems
  Immune system
   04611 Platelet activation
    102252921 (PIK3CD)
   04620 Toll-like receptor signaling pathway
    102252921 (PIK3CD)
   04650 Natural killer cell mediated cytotoxicity
    102252921 (PIK3CD)
   04660 T cell receptor signaling pathway
    102252921 (PIK3CD)
   04662 B cell receptor signaling pathway
    102252921 (PIK3CD)
   04664 Fc epsilon RI signaling pathway
    102252921 (PIK3CD)
   04666 Fc gamma R-mediated phagocytosis
    102252921 (PIK3CD)
   04670 Leukocyte transendothelial migration
    102252921 (PIK3CD)
   04062 Chemokine signaling pathway
    102252921 (PIK3CD)
  Endocrine system
   04910 Insulin signaling pathway
    102252921 (PIK3CD)
   04923 Regulation of lipolysis in adipocyte
    102252921 (PIK3CD)
   04915 Estrogen signaling pathway
    102252921 (PIK3CD)
   04914 Progesterone-mediated oocyte maturation
    102252921 (PIK3CD)
   04917 Prolactin signaling pathway
    102252921 (PIK3CD)
   04919 Thyroid hormone signaling pathway
    102252921 (PIK3CD)
  Digestive system
   04973 Carbohydrate digestion and absorption
    102252921 (PIK3CD)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102252921 (PIK3CD)
  Nervous system
   04725 Cholinergic synapse
    102252921 (PIK3CD)
   04722 Neurotrophin signaling pathway
    102252921 (PIK3CD)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102252921 (PIK3CD)
  Development
   04360 Axon guidance
    102252921 (PIK3CD)
   04380 Osteoclast differentiation
    102252921 (PIK3CD)
  Aging
   04211 Longevity regulating pathway - mammal
    102252921 (PIK3CD)
   04213 Longevity regulating pathway - multiple species
    102252921 (PIK3CD)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    102252921 (PIK3CD)
   05230 Central carbon metabolism in cancer
    102252921 (PIK3CD)
   05231 Choline metabolism in cancer
    102252921 (PIK3CD)
   05205 Proteoglycans in cancer
    102252921 (PIK3CD)
   05203 Viral carcinogenesis
    102252921 (PIK3CD)
   05210 Colorectal cancer
    102252921 (PIK3CD)
   05212 Pancreatic cancer
    102252921 (PIK3CD)
   05214 Glioma
    102252921 (PIK3CD)
   05221 Acute myeloid leukemia
    102252921 (PIK3CD)
   05220 Chronic myeloid leukemia
    102252921 (PIK3CD)
   05218 Melanoma
    102252921 (PIK3CD)
   05211 Renal cell carcinoma
    102252921 (PIK3CD)
   05215 Prostate cancer
    102252921 (PIK3CD)
   05213 Endometrial cancer
    102252921 (PIK3CD)
   05224 Breast cancer
    102252921 (PIK3CD)
   05222 Small cell lung cancer
    102252921 (PIK3CD)
   05223 Non-small cell lung cancer
    102252921 (PIK3CD)
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    102252921 (PIK3CD)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    102252921 (PIK3CD)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    102252921 (PIK3CD)
   04931 Insulin resistance
    102252921 (PIK3CD)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102252921 (PIK3CD)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    102252921 (PIK3CD)
   05166 HTLV-I infection
    102252921 (PIK3CD)
   05162 Measles
    102252921 (PIK3CD)
   05164 Influenza A
    102252921 (PIK3CD)
   05161 Hepatitis B
    102252921 (PIK3CD)
   05160 Hepatitis C
    102252921 (PIK3CD)
   05167 Kaposi's sarcoma-associated herpesvirus infection
    102252921 (PIK3CD)
   05169 Epstein-Barr virus infection
    102252921 (PIK3CD)
   05165 Human papillomavirus infection
    102252921 (PIK3CD)
   05146 Amoebiasis
    102252921 (PIK3CD)
   05142 Chagas disease (American trypanosomiasis)
    102252921 (PIK3CD)
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    102252921 (PIK3CD)
   01524 Platinum drug resistance
    102252921 (PIK3CD)
   01522 Endocrine resistance
    102252921 (PIK3CD)
Enzymes [BR:myb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     102252921 (PIK3CD)
Membrane trafficking [BR:myb04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    102252921 (PIK3CD)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Position
Un
AA seq 978 aa AA seqDB search
MPPGVDCPMEFWANEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKALWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKAGTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQP
EDYTLQVNGKQEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQV
QKSRTKPPPIPRKEPSSVSLWALEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCK
TVSSSEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADC
PIAWANLTLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVCSNPNTESAAALVICLP
EVAPHPVYYPALDKILELGRHGEHGRATXXXXXXXXXXXXXSGSGELYEHEKDLVWKMRH
EVQERFPEALARLLLVTKWNKHEDVAQVGWGLTLPGACRPQSRPSHGAPGPAASLPCRDD
ELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGL
IMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKSPKPQTKELMHLCMRQETYLE
ALSHLQSPLDPRILLAEVCVEQCTFMDSKMKPLWVMYSNEEAGGDGSVGIIFKNGDDLRQ
DMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLRSDTIANIQLNKSNMAA
TAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRENGQ
LFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTI
LRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRES
WKTKVNWLAHNVSKDNRQ
NT seq 2937 nt NT seq  +upstreamnt  +downstreamnt
atgcccccgggggtggactgccccatggaattctgggccaacgaggagaaccagagcgtg
gcggtggacttcctgctgcccacgggggtctatctgaacttccccgtgtcccgcaatgcc
aacctcagcaccatcaagaaggcgctgtggcaccgagcccagtatgagccgctcttccac
atgctcagcgaccccgaggcctacgtgttcacctgcgtcaaccagacggcggagcagcag
gagctggaggacgagcagcggcggctgtgcgacatccagcccttcctgcccgtcctgcgc
ctggtggcccgcgagggcgaccgggtcaagaagctcatcaactcgcagatcagcctcctc
attggcaaagccggcaccttgcgggtccccaaccgggccctcctggtcaacgtcaagttc
gagggcagtgaggagagcttcaccttccaggtgtccaccaaggacgtgcccctggcgctt
atggcctgcgccctgcggaagaaggccacggtgttccggcagcccctggtggagcagccc
gaggactacacgctgcaggtgaacggcaagcaggagtacctgtacggcagctacccgctc
tgccagttccagtacatctgcagctgcctgcacagcgggctgaccccccacctgaccatg
gtccactcctcctccatcctggccatgcgggacgagcagagcaacccggccccccaggtc
caaaaatcacgcaccaagccaccccccatccccaggaaggagccctcctccgtgtccctg
tgggccctggagcagcccttctgcgtggagctgatccagggcagcaaagtgaacgccgac
gagcggatgaagctggtggtgcaggccgggctcttccacggcaacgagacgctgtgcaag
acggtgtccagctcggaggtgagcgtgtgctcggagcccgtgtggaagcagcgcctggag
ttcgacatcaacgtgtgcgacctgccgcgcatggcccggctctgcttcgcgctgtacgcc
gtcatcgagaaggccaagaaggctcgctccaccaagaagaagtccaagaaggcggactgc
cccatcgcctgggctaacctcaccctgttcgactacaaggaccagctcaagactggcgag
cgctgcctctacatgtggccctcggtcccagacgagaaaggggagctgctgaaccccaca
ggaaccgtgtgcagcaaccccaacaccgagagtgctgccgccctggtcatctgtctcccc
gaggtggcgccccaccccgtgtactaccccgccctggacaagatcctggagctggggcgg
cacggggagcacgggcgcgccacnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn
nnntccggttccggggagctgtacgagcacgagaaggacctggtgtggaagatgcgccac
gaggtgcaggagcgcttccccgaggcgctggcccggctgctgctggtcaccaagtggaac
aagcacgaggacgtggcccaggtggggtggggactgaccctccctggggcctgcagaccc
cagtcccgcccaagccacggagctccaggcccagcagcctcgcttccctgcagggacgac
gagctgttccagtacctgctgcagctggtgcaggtgctgaagtacgagtcctacctggac
tgcgagctgacgaaattcctgctggaccgggcgctggccaaccgcaagatcggccacttc
ctcttctggcacctccgctccgagatgcacgtgccctcggtggccctacgcttcggcctc
atcatggaggcctactgcaggggcagcacccaccacatgaaggtgctgatgaagcagggg
gaggcgctgagcaagctgaaggccctgaacgactttgtcaaagtgagctcccagaagagc
cccaagccgcagaccaaggagctgatgcacctgtgcatgcgccaggagacctacctggag
gccctgtcccacctgcagtccccgctggaccccaggatcctgctggcggaagtctgtgtg
gagcagtgcaccttcatggactccaagatgaagccgctgtgggtcatgtacagcaatgag
gaggcgggcggcgacggcagcgtgggcatcatctttaagaacggggacgacctccgccag
gacatgctgacgctgcagatgatccagctcatggacatcctgtggaagcaggaggggctg
gacctgaggatgaccccctacggctgcctctccaccggggaccgcacgggcctcatcgag
gtggtgcttcgctcggacaccattgccaacatccagctcaacaagagcaacatggcagcc
acggccgctttcaacaaggacgccctgctcaactggctcaagtccaagaaccctggggag
gccctggacagggccatcgaggagttcaccctctcctgcgctggctactgtgtggccacg
tacgtgctgggcatcggcgaccggcacagcgacaacatcatgatccgcgagaacgggcag
ctgttccacattgattttggccactttctggggaatttcaagaccaagtttggaatcaac
cgtgagcgagtcccattcatcctcacctatgactttgtccatgtgattcagcaggggaag
actaacaacagtgagaagtttgaaaggttccgtggctactgcgagagagcctacaccatc
ctgaggcgccatgggctgctcttcctccacctcttcgccctgatgcgggcggcaggcctg
ccagagctcagctgctccaaagacatccagtatctcaaggactcgctggcactggggaaa
acggaggaggaggcgctgaagcacttccgcgtgaagttcaacgaggcgctgcgggagagc
tggaagaccaaagtgaactggctggcccacaacgtgtccaaagacaaccggcaatag

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