KEGG   Myotis brandtii (Brandt's bat): 102260487Help
Entry
102260487         CDS       T02920                                 

Gene name
PIK3CB
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
myb  Myotis brandtii (Brandt's bat)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Signaling pathways regulating pluripotency of stem cells
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Central carbon metabolism in cancer
Choline metabolism in cancer
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:myb00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102260487 (PIK3CB)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    102260487 (PIK3CB)
   04015 Rap1 signaling pathway
    102260487 (PIK3CB)
   04012 ErbB signaling pathway
    102260487 (PIK3CB)
   04370 VEGF signaling pathway
    102260487 (PIK3CB)
   04630 Jak-STAT signaling pathway
    102260487 (PIK3CB)
   04668 TNF signaling pathway
    102260487 (PIK3CB)
   04066 HIF-1 signaling pathway
    102260487 (PIK3CB)
   04068 FoxO signaling pathway
    102260487 (PIK3CB)
   04070 Phosphatidylinositol signaling system
    102260487 (PIK3CB)
   04024 cAMP signaling pathway
    102260487 (PIK3CB)
   04022 cGMP - PKG signaling pathway
    102260487 (PIK3CB)
   04151 PI3K-Akt signaling pathway
    102260487 (PIK3CB)
   04152 AMPK signaling pathway
    102260487 (PIK3CB)
   04150 mTOR signaling pathway
    102260487 (PIK3CB)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    102260487 (PIK3CB)
  Cell growth and death
   04210 Apoptosis
    102260487 (PIK3CB)
  Cellular commiunity
   04510 Focal adhesion
    102260487 (PIK3CB)
   04550 Signaling pathways regulating pluripotency of stem cells
    102260487 (PIK3CB)
 Organismal Systems
  Immune system
   04611 Platelet activation
    102260487 (PIK3CB)
   04620 Toll-like receptor signaling pathway
    102260487 (PIK3CB)
   04650 Natural killer cell mediated cytotoxicity
    102260487 (PIK3CB)
   04660 T cell receptor signaling pathway
    102260487 (PIK3CB)
   04662 B cell receptor signaling pathway
    102260487 (PIK3CB)
   04664 Fc epsilon RI signaling pathway
    102260487 (PIK3CB)
   04666 Fc gamma R-mediated phagocytosis
    102260487 (PIK3CB)
   04670 Leukocyte transendothelial migration
    102260487 (PIK3CB)
   04062 Chemokine signaling pathway
    102260487 (PIK3CB)
  Endocrine system
   04910 Insulin signaling pathway
    102260487 (PIK3CB)
   04915 Estrogen signaling pathway
    102260487 (PIK3CB)
   04914 Progesterone-mediated oocyte maturation
    102260487 (PIK3CB)
   04917 Prolactin signaling pathway
    102260487 (PIK3CB)
   04921 Oxytocin signaling pathway
    102260487 (PIK3CB)
   04919 Thyroid hormone signaling pathway
    102260487 (PIK3CB)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102260487 (PIK3CB)
  Digestive system
   04973 Carbohydrate digestion and absorption
    102260487 (PIK3CB)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102260487 (PIK3CB)
  Nervous system
   04725 Cholinergic synapse
    102260487 (PIK3CB)
   04722 Neurotrophin signaling pathway
    102260487 (PIK3CB)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102260487 (PIK3CB)
  Development
   04380 Osteoclast differentiation
    102260487 (PIK3CB)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    102260487 (PIK3CB)
   05230 Central carbon metabolism in cancer
    102260487 (PIK3CB)
   05231 Choline metabolism in cancer
    102260487 (PIK3CB)
   05205 Proteoglycans in cancer
    102260487 (PIK3CB)
   05203 Viral carcinogenesis
    102260487 (PIK3CB)
   05210 Colorectal cancer
    102260487 (PIK3CB)
   05212 Pancreatic cancer
    102260487 (PIK3CB)
   05214 Glioma
    102260487 (PIK3CB)
   05221 Acute myeloid leukemia
    102260487 (PIK3CB)
   05220 Chronic myeloid leukemia
    102260487 (PIK3CB)
   05218 Melanoma
    102260487 (PIK3CB)
   05211 Renal cell carcinoma
    102260487 (PIK3CB)
   05215 Prostate cancer
    102260487 (PIK3CB)
   05213 Endometrial cancer
    102260487 (PIK3CB)
   05222 Small cell lung cancer
    102260487 (PIK3CB)
   05223 Non-small cell lung cancer
    102260487 (PIK3CB)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    102260487 (PIK3CB)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    102260487 (PIK3CB)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    102260487 (PIK3CB)
   05166 HTLV-I infection
    102260487 (PIK3CB)
   05162 Measles
    102260487 (PIK3CB)
   05164 Influenza A
    102260487 (PIK3CB)
   05161 Hepatitis B
    102260487 (PIK3CB)
   05160 Hepatitis C
    102260487 (PIK3CB)
   05169 Epstein-Barr virus infection
    102260487 (PIK3CB)
   05146 Amoebiasis
    102260487 (PIK3CB)
   05145 Toxoplasmosis
    102260487 (PIK3CB)
   05142 Chagas disease (American trypanosomiasis)
    102260487 (PIK3CB)
Enzymes [BR:myb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     102260487 (PIK3CB)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 1091 aa AA seqDB search
MCFNFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISHIKQMLW
AQIHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
ESSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRLTIHWKEDE
VSPYDYVLQISGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGT
ELLCKTIVSSEISGKNDHVWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTIN
ASKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQT
NPYTENATALHIRFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLAVLKEI
LDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKL
PPREALELLDFNYPDQYVREYAVGCLRQMSKRIQSRIGKGKRFMGQSLEETSDEELSQYL
LQLVQVLKYEPFLDCALSRFLLERALANRRIGQFLFWHLRSEVHIPAISIQFGVILEAYC
RGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQ
SPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVVVMFKNGDDLRQDMLTLQM
LRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEIVSNSETIADIQLNSSNVAAAAAFNKD
ALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKNGQLFHIDFG
HILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNL
FITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNW
MAHTVRKDYRS
NT seq 3276 nt NT seq  +upstreamnt  +downstreamnt
atgtgcttcaatttcataatgcctcctgctatggcagacatccttgacatctgggcagtg
gattcacagatagcatctgatggctccatacctgtggatttccttttgcccactgggatt
tatatccagttggaggtacctcgggaagctaccatttctcatattaaacagatgttgtgg
gcacagattcataattacccaatgtttaacctccttatggaaattgactcctatatgttt
gcatgtgtgaatcaaactgctgtatatgaggagctcgaagatgaaacaagaagactctgt
gatgtcagaccttttcttccagttctcaaattagtgactagaagttgtgacccaggggaa
aaattagactcaaaaattggagtccttataggaaaaggtttgcatgaatttgatgccttg
aaggatcctgaagtgaatgaattccgaataaaaatgcgtaaattcagtgaggaaaagatt
cagtcgcttgtgggattgtcttggatggactggctaaagcaaacatatccaccagagcat
gaatcatccatccttgaaaacttagaagataaactttatggaggaaagctcattgtggct
gtgcattttgaaaattgtcaggatgtgtttagctttcaagtatctcctaatatgaatcct
ataaaaataaatgaactagcaatccaaaaacgtttgactattcattggaaagaggatgaa
gttagcccctatgactatgtgctgcaaatcagtgggagagtagaatacgtgtttggtgat
cacccactaatccagttccagtatatccggaactgtgtaatgaacaggaccttgccccat
tttatacttgtggaatgttgcaagatcaaaaagatgtatgaacaggaaatgattgccata
gaggctgccataaatcgaaattcatctaaccttccccttcctttaccaccaaagaaacga
attatttctcatgtttgggaaaataacaaccctttccaaattgtcttggttaagggaaat
aaacttaacacagaagaaactgtaaaagttcatgtcagggctggcctttttcatggtact
gaactcctgtgtaaaaccatcgtaagctcagagatatcagggaaaaatgatcatgtttgg
aatgaaccactggaatttgatattaatacttgtgacctgccacgaatggctagattatgt
tttgctgtttatgcagttttggataaagtgaaaacgaagaaatcaactaaaacaattaat
gcctctaaatatcagaccatcaggaaatctgggaaagtgcattatcctgtagcatgggta
aatacgatggtttttgactttaaaggacagttgagatctggagacataatattgcacagc
tggtcttcatttcctgatgaacttgaagaaatgttgaatccaatgggaactgttcaaaca
aatccatatactgagaatgcaacagctttgcatatcagattcccagagaataaaaaacaa
ccttattattaccctccctttgataagattatcgaaaaggcagctgagattgcaagcagt
gatagtgctaatgtatcaagtcggggtggaaaaaagtttcttgctgtactgaaagaaatc
ttggacagggatcccttgtctcagctgtgtgagaatgaaatggatcttatttggactttg
cgacaagactgcagagagaacttcccacagtcactgccaaagttattactatcgatcaag
tggaataaacttgaggatgttgctcagcttcaggcactacttcagatttggcctaaacta
cctcctcgggaggccctggagcttcttgatttcaactatccagatcagtacgttcgggaa
tatgctgtaggctgcctgcgacagatgagcaaaaggatacaaagcagaattggcaaagga
aaaagattcatggggcaaagtctggaggaaaccagcgatgaagaactctcgcaatatctt
ttacaactggtgcaagttttaaaatatgagccttttcttgattgtgccctctctagattc
ctattagaaagagcacttgctaatcggaggatagggcagtttctattttggcaccttaga
tcagaagtgcacattcctgctatctccatacagtttggtgtcatccttgaagcgtactgc
cggggaagcgtagggcacatgaaagtgctttccaagcaggttgaagcactcaataaatta
aaaactttaaatagtttaatcaaactgaatgcagtgaagctaaacagagccaaaggcaaa
gaggccatgcacacttgtttaaaacagaatgcttaccgggaagccctctctgacctgcag
tcccctctgaacccatgcgtcatcctctcagaactctatgttgaaaagtgtaaatacatg
gattctaaaatgaagcctttgtggctggtatacaacaacaaggtatttggtgaggattca
gtcgtagtgatgtttaaaaatggtgatgatttacgacaggatatgttgacactccaaatg
ctgcgcttgatggatttactctggaaagaagccggtctggatcttcggatgttgccttat
ggctgtttagcgacaggagatcgctcaggcctcattgaaattgtgagcaactctgaaaca
attgctgacattcagctgaacagtagcaatgtggctgctgcagcagccttcaataaagat
gcccttctgaactggcttaaagaatacaattctggggatgacttggaccgagccattgag
gagtttaccctgtcctgtgctggctactgtgtagcttcttatgtccttggaattggtgac
agacatagtgacaacatcatggtaaagaaaaatggccagctcttccacattgactttgga
catattcttggaaattttaagtctaaatttggcattaaaagggagcgagtgccttttatt
cttacctatgatttcattcatgtgattcaacaaggaaaaacaggaaacacagaaaagttt
ggccggttccgccagtgttgtgaggatgcctatctgattttacgacggcacgggaatctc
ttcatcactctctttgcactgatgctgactgcagggcttcctgagctcacatcagtcaag
gatatacagtatcttaaggactcacttgccttagggaagagtgaagaagaagcactcaag
caatttaagcaaaaatttgatgaggcactcagggaaagctggactactaaggtgaactgg
atggcccacacggttcggaaagactacagatcttaa

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