KEGG   Myotis davidii (David's myotis): 102764267
Entry
102764267         CDS       T02992                                 
Symbol
MTHFR
Name
(RefSeq) methylenetetrahydrofolate reductase
  KO
K25004  methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.53]
Organism
myd  Myotis davidii (David's myotis)
Pathway
myd00670  One carbon pool by folate
myd01100  Metabolic pathways
myd01523  Antifolate resistance
Brite
KEGG Orthology (KO) [BR:myd00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    102764267 (MTHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    102764267 (MTHFR)
Enzymes [BR:myd01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.53  methylenetetrahydrofolate reductase (NADPH)
     102764267 (MTHFR)
SSDB
Motif
Pfam: MTHFR
Other DBs
NCBI-GeneID: 102764267
NCBI-ProteinID: XP_006766778
Position
Un
AA seq 698 aa
MDHLKPEVLPARHCCPSLGMQALEAGIMRFSVPPSISRSSAMVNEPRGNGSPNPRLEGSS
SGMESPKDSSRCSSPGLDPERHERLREKMRRRMESGDKWFSLEFFPPRTAQGAVNLISRF
DQMGAGGPLFIDVTWHPAGDPGSDKETSSMAIASAAVNYCGLETVLHMTCCRQSQEEITG
HLHRAKQLGLKNILALRGDPVGDQWEEEEGCFRHATDLVKLIRSEFGDYFDICVAGYPKG
HPDAESFEDDLKHLKGKVSAGADFIITQLFFEAETFFRFVKACSAIGITCPILPGIFPIQ
GYHSLRQLVKLSKLEVPQKIRDVIEPIKDNDAAICNYGIDHAVSLCQELLASGLVPGLHF
YTLNRRMATTEVLKRLGMWAEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQD
WDEFPNGRWGHSSSPAFGELKDYYLFYLTNKAPREELLKMWGEELTSEESVFEVFVHYLS
GEPNQSGCRVTCLPWNDEPLAAETSLMKEELLRVNRQGILTINSQPNINGKPSSDPVVGW
GPSGGYVFQKAYLEFFTSRETVGALLQVLKKYEQRVNYHIVDVKGENITNAPELQPNAVT
WGIFPGREIIQPTVVDPGSFMFWKDEAFALWVKQWGKLYDEESPSRMIIQYIHDNYFLVN
LVDNEFPLDNCLWQVVEDTFELLNRPGARADRLRDPAP
NT seq 2097 nt   +upstreamnt  +downstreamnt
atggaccatctaaaacccgaggtcctcccagccaggcactgctgcccctccctaggaatg
caggccctggaggctggcatcatgaggttctcagtgccaccctccatcagcaggagctca
gccatggtgaacgaacccagagggaatggcagccccaacccccgcctggagggcagcagc
agcggcatggagagccccaaggatagttcgaggtgttcctcgccagggctggaccctgag
cggcacgagagactcagggagaagatgaggcggaggatggagtccggtgacaagtggttc
tctctggagttcttccctccgcggacggcgcagggcgctgtcaatctcatctcgaggttt
gaccagatgggggcaggcggccccctcttcatagatgtgacctggcacccagcaggagac
cctggctcggacaaggagacctcctccatggccatcgccagcgctgctgtcaactactgt
ggcctggagaccgtgctgcacatgacctgctgccgtcagagccaggaggagatcacgggc
catctgcacagggccaagcagctgggcctgaagaacatcctggcactgagaggagaccct
gtaggcgaccagtgggaggaagaggaaggctgtttccgccacgccacagacctggtgaag
ctcatccgcagcgagtttggtgactactttgacatctgtgtggcaggttaccccaagggc
caccccgacgccgagagctttgaggacgacctgaagcacttgaaggggaaggtgtctgcg
ggagccgacttcatcatcacccagcttttcttcgaggctgagacgttcttccgctttgtg
aaggcttgttccgcgataggcatcacctgccccatcctccccggcatcttccccattcag
ggctaccactccctgcggcagctcgtgaagctgtccaagctggaggtgccgcagaagatc
agggacgtgatcgagcccatcaaggacaacgacgctgccatctgcaactatggcatcgac
catgccgtgagcctgtgccaggagctgctggccagtggcctggtgccgggcctgcacttc
tacaccctcaaccgcaggatggccaccaccgaggtgctgaagcgcctgggcatgtgggcc
gaggaccccaggcgtcccctgccctgggctgtcagtgcccaccccaagcgccgggaggaa
gatgtgcgtcccatcttctgggcctccagaccgaagagttacatctaccgcacccaggac
tgggacgagttccccaatggccgctggggccattcctcctcgccagccttcggggagctg
aaggactactacctcttctacctgacgaacaaggccccgagggaggagctgctgaagatg
tggggggaggagctgaccagtgaagaaagtgtctttgaagtctttgtccattacctctcc
ggggagccaaaccagagcggctgtcgagtcacttgcctgccctggaatgacgagcccctg
gcggccgagaccagcctgatgaaggaggagctgctgcgcgtgaaccggcagggcatcctc
accatcaactcccagcccaacatcaatgggaagccgtcctctgacccggtcgtgggctgg
ggccccagcgggggctatgtcttccagaaggcctacttggagttcttcacttcccgagag
acggtgggggcactcctgcaggtgctgaagaagtacgagcagcgggtgaactaccacatc
gtggacgtgaagggtgaaaacatcaccaatgcccccgagctgcagcccaacgctgtcact
tggggcatcttccctgggcgagagatcatccagcccacggtggtggatcctggcagcttc
atgttctggaaggacgaagccttcgccctgtgggtgaagcagtggggcaagctgtacgac
gaggagtccccgtcccgtatgatcatccaatacatccacgacaactacttcctcgtcaac
ctggtagacaacgagtttccgctggacaactgcctgtggcaggtggtggaagacactttt
gaacttctcaacagacccggagcgagagcggacaggctccgtgaccctgcaccctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (1)   
   Pfam (1)   
All databases (24)   

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