KEGG   Myotis davidii (David's myotis): 102764844
Entry
102764844         CDS       T02992                                 
Symbol
HSPA5
Name
(RefSeq) heat shock protein family A (Hsp70) member 5
  KO
K09490  endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
Organism
myd  Myotis davidii (David's myotis)
Pathway
myd03060  Protein export
myd04141  Protein processing in endoplasmic reticulum
myd04612  Antigen processing and presentation
myd04918  Thyroid hormone synthesis
myd05012  Parkinson disease
myd05014  Amyotrophic lateral sclerosis
myd05020  Prion disease
myd05022  Pathways of neurodegeneration - multiple diseases
myd05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:myd00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03060 Protein export
    102764844 (HSPA5)
   04141 Protein processing in endoplasmic reticulum
    102764844 (HSPA5)
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    102764844 (HSPA5)
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    102764844 (HSPA5)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    102764844 (HSPA5)
   05014 Amyotrophic lateral sclerosis
    102764844 (HSPA5)
   05020 Prion disease
    102764844 (HSPA5)
   05022 Pathways of neurodegeneration - multiple diseases
    102764844 (HSPA5)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102764844 (HSPA5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:myd03110]
    102764844 (HSPA5)
   04131 Membrane trafficking [BR:myd04131]
    102764844 (HSPA5)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:myd04147]
    102764844 (HSPA5)
Enzymes [BR:myd01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.4  Acting on acid anhydrides to facilitate cellular and subcellular movement
    3.6.4.10  non-chaperonin molecular chaperone ATPase
     102764844 (HSPA5)
Chaperones and folding catalysts [BR:myd03110]
 Heat shock proteins
  HSP70 / DNAK
   102764844 (HSPA5)
Membrane trafficking [BR:myd04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   ER-Golgi intermediate compartment (ERGIC) proteins
    102764844 (HSPA5)
Exosome [BR:myd04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   102764844 (HSPA5)
  Exosomal proteins of other body fluids (saliva and urine)
   102764844 (HSPA5)
  Exosomal proteins of colorectal cancer cells
   102764844 (HSPA5)
SSDB
Motif
Pfam: HSP70 MreB_Mbl Hydantoinase_A FtsA DDR FGGY_C ParM_N
Other DBs
NCBI-GeneID: 102764844
NCBI-ProteinID: XP_006768631
UniProt: L5LK85
Position
Un
AA seq 654 aa
MKLSLVAAVLLLLGAARADEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR
ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV
EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ
RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG
VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS
SQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV
LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC
PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG
TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER
MVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEE
KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTEEEEPADRDEL
NT seq 1965 nt   +upstreamnt  +downstreamnt
atgaagctctctctggtggctgcggtgctgctgctgctcggcgcagcgcgggccgatgag
gaggacaagaaggaggacgtcggcacggtggtcggcatcgatctggggaccacctactcc
tgcgtcggggtgtttaagaacggccgcgtggagatcatcgccaacgaccagggcaaccgc
atcactccgtcttatgtggccttcactcctgaaggggagcgtctgatcggcgatgcagcc
aagaaccagctcacctccaaccccgagaacacggtcttcgatgccaagcggctcatcggc
cgcacgtggaacgacccgtctgtgcagcaggacatcaagttcttgcctttcaaggtggtt
gaaaagaaaactaaaccatacatccaagttgatattggaggtgggcaaacaaagactttt
gctcctgaagaaatatctgccatggttctcactaaaatgaaggaaaccgctgaggcttat
ttgggaaagaaggtcacccatgcagttgttaccgtaccagcctatttcaatgatgcccaa
cgccaggcaaccaaagatgctgggactattgctggattgaatgttatgaggatcatcaat
gagccgacagcagctgctatcgcttatggcctagataaaagggaaggggagaagaacatc
cttgtgtttgaccttggtggtggaaccttcgacgtgtctcttctcaccattgataatggt
gtcttcgaagttgtggccacgaatggggatactcatctgggtggagaagattttgaccag
cgtgtcatggaacacttcatcaagctctacaaaaagaagactggcaaagatgttaggaaa
gacaacagagctgtgcagaaactccggcgggaggtagaaaaggccaaacgggccctgtct
tctcaacaccaagcaagaattgaaatcgagtccttctttgaaggagaagacttctctgag
accctgactcgggccaaatttgaagaactgaacatggacctgttccgctctaccatgaag
cctgtccagaaagtgctggaagattctgatttgaagaagtctgatattgatgaaattgtt
cttgttggtggctccactagaatcccaaagattcaacaactggttaaagagttcttcaat
ggcaaggagccatcccgtggcataaacccagatgaggctgtagcttatggtgctgctgtc
caggctggtgtactctctggtgatcaagatacaggtgatctggtactgcttgacgtatgt
ccccttacgcttggtattgaaactgtgggaggtgtcatgactaagctgattccaaggaac
actgtggtgcccaccaagaagtcacagatcttttctacagcctctgataatcaaccaact
gttacaatcaaggtttatgaaggtgaacgccccctgacaaaagacaatcatctcctggga
acctttgatctgactggaattcctcctgctcctcgtggggtcccacagattgaagtcacc
tttgagatagatgtgaatggcattctccgagtgacagctgaagacaaaggtacaggcaac
aaaaataagatcacaattaccaatgatcaaaatcgcctgacacctgaagaaattgaaagg
atggtcaatgatgcagagaagtttgctgaggaggacaaaaagctcaaggagcgcattgat
actagaaatgagttggaaagttatgcctattctctaaagaatcaaattggagataaagaa
aagctgggaggtaaactttcctctgaagataaggagaccatggaaaaagctgtagaggaa
aagattgaatggctggaaagtcaccaagatgctgacattgaagatttcaaagccaaaaag
aaggaactggaagaaattgttcagccaattatcagcaaactctatggaagtgcaggccct
cccccaactgaggaagaggaaccagcagacagggatgagttgtag

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