KEGG   Myotis davidii: 102766590Help
Entry
102766590         CDS       T02992                                 

Gene name
INSR
Definition
(RefSeq) insulin receptor
  KO
K04527  
insulin receptor [EC:2.7.10.1]
Organism
myd  Myotis davidii
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phospholipase D signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adherens junction
Insulin signaling pathway
Ovarian steroidogenesis
Regulation of lipolysis in adipocytes
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:myd00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    102766590 (INSR)
   04015 Rap1 signaling pathway
    102766590 (INSR)
   04010 MAPK signaling pathway
    102766590 (INSR)
   04066 HIF-1 signaling pathway
    102766590 (INSR)
   04068 FoxO signaling pathway
    102766590 (INSR)
   04072 Phospholipase D signaling pathway
    102766590 (INSR)
   04022 cGMP - PKG signaling pathway
    102766590 (INSR)
   04151 PI3K-Akt signaling pathway
    102766590 (INSR)
   04152 AMPK signaling pathway
    102766590 (INSR)
   04150 mTOR signaling pathway
    102766590 (INSR)
 Cellular Processes
  Cellular community - eukaryotes
   04520 Adherens junction
    102766590 (INSR)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    102766590 (INSR)
   04923 Regulation of lipolysis in adipocyte
    102766590 (INSR)
   04913 Ovarian Steroidogenesis
    102766590 (INSR)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102766590 (INSR)
  Aging
   04211 Longevity regulating pathway - mammal
    102766590 (INSR)
   04213 Longevity regulating pathway - multiple species
    102766590 (INSR)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    102766590 (INSR)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    102766590 (INSR)
   04931 Insulin resistance
    102766590 (INSR)
Enzymes [BR:myd01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     102766590 (INSR)
Protein kinases [BR:myd01001]
 Tyrosine protein kinases
  InsR family [OT]
   102766590 (INSR)
Enzyme-linked receptors [BR:myd01020]
 Receptor tyrosine kinases
  RTK class II (Insulin receptor family)
   102766590 (INSR)
Cytokine receptors [BR:myd04050]
 Receptor tyrosine kinase
  RTK class II (Insulin receptor family)
   102766590 (INSR)
CD molecules [BR:myd04090]
 Proteins
  102766590 (INSR)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Position
Un
AA seq 1386 aa AA seqDB search
MYGRGFSQGQDPLSDAPPLILKTHHCVLAHLSHFLHIFTLVCPSMDIRNNFTRLHELANC
SIIEGHLQILLMFRTRPEDFRDLSFPKLVMITDYLLLFRVYGLESLKDLFPNLTVIRGSR
LFFNYALVIFEMVHLKELGLYSLMNITRGAVRIEKNNDLCYLATIDWSRILDSVEDNYIV
LNKDDNEECGDICPGTAKGKTSCPATVINGQFVERCWTHSHCQKVCPTSCKSHGCTAEGL
CCHPECLGSCSEPNDPTKCVACRHFYLDGRCVETCPAPYYHFRDWRCVNFSFCLDLHNKC
KNSRRQGCHQYVIHNNKCFGGPVCPDPLPFFLLSLMCTPCLGPCPKVCHILEGEKTIDSV
TAAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRK
LRLIQGNTLEVGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEE
ISGTKGRQERTDIALKTNGDQASCENELLKFSYIRTSYDKIMLKWEPYWPPDFRDLLGFM
LFYKEAPYRNVTEFDGQDACGSNSWTVVDIDPPPRSTDPKLQNHPGWLMRSLKPWTQYAI
FVKTLVTFSDERRTYGAKSDIIYIQTNATNPSVPLDPISVSNSSSQIILKWKPPSDPNGN
ITHYLVFWERQAEDSELYELDYCLKGLKLPSRTWSPPSELDGSQKHNQSEYDEAAGECCS
CPKTDSQIQKELEESSFRKTFENYLHNVVFVPRTISSGPGAEDSRSSRKRRALGDEGNVT
MAVPTAPGFPNTSTIVPTSSEEPRPFEKVVNKESLVISGLRHFTGYRIELQACNQDFPEE
RCSVAAYISARTMPEAKADDIVGPVTHEIFENNIVHLMWQEPKHPNGLIVLYEVSYRRYG
DEELHLCVSRRHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEATYFYVTNYLDVPS
NIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQSDGPVGPLYASSNPEYLSASDVFPCSVYV
PDEWEVPREKITLLRELGQGSFGMVYEGNAKDIIKGEAETRVAVKTVNESASMRERIEFL
NEASVMKGFACHHVVRLLGVVSKGQPTLVVMELMTHGDLKSHLRSLRPDAENNPGRPPPT
LQEMFQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRK
GGKGLLPVRWMAPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDG
GYLDIPDNCPERLSELMSMCWHFNPKMRPTFLEVVDLLKDNLHPSFPEVSFFYSEENKAP
ENDELEMEFEDMESVPLDRSSHCQREEDGGCSLALKRNYEDHMSYSHMNGGKKNGRVLTL
PRSSPS
NT seq 4161 nt NT seq  +upstreamnt  +downstreamnt
atgtatggaaggggatttagccaagggcaggaccctctgagcgatgccccgccgctaatt
cttaaaacccaccattgtgtgttagctcacctgtcacactttctgcatatttttactcta
gtgtgtcccagcatggacatccggaacaacttcacgaggctgcacgagctggctaactgc
tcgatcatcgaaggacatttgcagatactgttgatgttcagaacaaggcctgaggatttc
cgagacctcagtttccccaaactcgtcatgatcactgattacttgctgctgtttcgggtc
tatgggctggagagcctgaaggacctattccccaacctcacggtcatccggggctcccgc
ctcttcttcaactacgcgctggtcatcttcgagatggtccacctgaaggagctgggcctg
tacagcctgatgaacatcacccggggggctgtccgcatcgagaagaacaacgacctctgc
tacctggctaccatcgactggtcgcgcatcctggactcggtggaggataattacatcgtg
ctgaacaaagacgacaatgaagagtgtggggacatctgtccaggcactgcgaagggcaag
accagctgccctgccaccgtcatcaacgggcagtttgtcgaacggtgttggactcacagc
cattgccagaaagtctgcccgaccagctgcaagtcgcacggctgcactgctgaaggcctc
tgctgccaccccgagtgcctgggcagctgctccgagcccaacgaccctaccaagtgcgtg
gcctgccgccacttctacctggacgggaggtgcgtggagacctgcccagccccgtactac
cacttccgggactggcgctgtgtgaacttcagcttctgcctggacctgcacaacaaatgc
aagaactcgcggcggcagggctgccatcagtacgtcattcacaacaacaagtgctttggg
ggtcctgtgtgccctgaccctcttcctttctttttactcagcttgatgtgcactccgtgt
ctgggcccctgtcccaaggtctgtcacatcctggaaggtgagaagaccatcgactcagtg
acagctgcccaggagcttcgagggtgcaccgtcatcaacgggagcctcatcatcaacatc
cgtgggggcaacaacctggcagctgagctcgaggccaacctcggcctcattgaggaaatc
tcagggtatctgaaaatccgccgttcctacgcgctagtgtcactttccttcttccggaag
ttacgtctgattcaggggaataccttggaagtcgggaactactctttctatgccttggac
aaccagaacctaaggcagctatgggactggagcaaacacaacctcaccataactcagggg
aaactcttcttccactataatcccaaactctgcttgtcggaaattcacaagatggaagaa
atttcaggaaccaagggacgccaggagaggaccgacattgccctgaagactaatggggac
caggcgtcctgtgaaaatgaattacttaaattttcttacatccggacatcttatgacaag
atcatgctgaaatgggagccgtactggccccctgacttccgagacctcctggggttcatg
ctcttctacaaagaggccccttaccggaacgtgacggagtttgatgggcaggatgcgtgt
ggatccaacagctggacggtggtggacattgacccgcctccgaggtccactgaccccaag
ttacagaaccatcctgggtggctgatgcggagcctcaagccctggactcagtatgccatc
ttcgtgaagaccttggtcaccttttctgatgaacgccgcacatatggggccaagagcgat
atcatctatatccagacaaatgccaccaatccttccgtccccttggatcccatctcggtt
tctaactcttcatcccagattatcttgaagtggaagcctccctccgaccccaacggcaac
atcacacactacctggttttctgggagaggcaggcggaagacagtgagctgtatgagctg
gattattgcctcaaagggttgaagctgccctcccggacctggtccccaccatctgagttg
gatggttcccagaagcacaaccagagcgagtacgacgaggctgccggcgagtgctgctcc
tgcccgaagactgactctcagattcagaaggaactggaggagtcctcgttcaggaagact
tttgagaattacctgcacaatgtggtcttcgtccccagaacaatctcttcaggccctggt
gctgaggacagtaggtcgtcgagaaaacgcagggcccttggtgacgagggtaacgtgacg
atggctgtgcccacagctccgggtttccccaacacctcaaccatcgtgcccacaagctcg
gaggagccgcggcccttcgagaaagtggtgaacaaggagtcgctggtcatctcgggcctg
cgccacttcactggctaccgcatcgagctgcaggcttgcaaccaggatttccccgaggag
aggtgcagcgtggccgcctacatcagcgccaggaccatgcccgaagccaaggcagatgac
attgttggccccgtgacccatgaaatcttcgagaacaacatcgttcatttaatgtggcag
gagccaaagcacccgaacggtctgattgtgctgtatgaagtgagctatcggcgatacgga
gatgaggagctgcacctgtgtgtgtcccgcaggcacttcgccctggagcggggctgccgg
ctgcgcgggctgtcacccgggaattacagcgtgagagtccgggccacctccctggcgggc
aatggttcctggacagaagccacctatttctatgtgacaaactacttagacgtcccctcc
aatattgcaaaaatcatcatcggccccctcatctttgtcttcctcttcagtgttgtgatt
ggaagtatttacctattcctgaggaagaggcagtcagacgggccggtgggaccactctat
gcttcttcaaaccccgagtacctcagtgccagcgatgtgttcccatgttctgtgtatgtg
ccggacgagtgggaggtgccacgggagaagatcaccctcctgcgagagctggggcagggc
tccttcggcatggtgtacgagggcaacgccaaggacatcatcaagggcgaggcggagact
cgagtggcggtgaagacggtcaacgagtcggccagcatgcgggagcggatcgagtttctc
aacgaggcctccgtcatgaaaggcttcgcctgccatcacgtggtccgcctcctcggagtg
gtgtccaaaggccagcccacgctggtggtgatggagctcatgacgcacggagacctgaag
agccacctgcgctccctgcggcctgacgctgagaataaccccggccggcctcccccgacc
ctgcaagagatgtttcagatggcagcggagattgctgacgggatggcatacctgaacgcc
aagaagtttgtgcaccgggacctcgcagctcgaaactgcatggtcgcccacgattttacc
gtcaaaattggagactttggaatgaccagagacatctacgaaacggattattaccggaaa
ggtggcaaaggtctgcttcctgtgaggtggatggcacctgaatctttgaaggacggggtc
tttaccgcttcttccgacatgtggtccttcggtgtggtcctttgggaaatcaccagcttg
gcagaacagccttaccaaggcctctctaatgagcaggtgttgaaattcgttatggatgga
gggtatctggatatccccgacaattgtccagagagactcagtgagttaatgagcatgtgc
tggcacttcaaccccaagatgaggccgaccttcctggaggtggttgacctgcttaaggac
aacctgcaccccagctttccggaagtttccttcttctacagcgaggagaacaaggcacct
gagaacgatgagttggagatggagtttgaggacatggagagtgtacccctggatcggtcc
tcacactgtcagagggaggaggatgggggctgttcgctggccctaaagcggaattacgag
gatcacatgtcctacagccacatgaatgggggcaagaaaaacggacgcgtcctgactctg
ccacggtccagtccttcctaa

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