KEGG   Myotis davidii (David's myotis): 102773641
Entry
102773641         CDS       T02992                                 
Symbol
DOT1L
Name
(RefSeq) DOT1 like histone lysine methyltransferase
  KO
K11427  [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360]
Organism
myd  Myotis davidii (David's myotis)
Pathway
myd00310  Lysine degradation
myd01100  Metabolic pathways
myd05202  Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:myd00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    102773641 (DOT1L)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    102773641 (DOT1L)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:myd03036]
    102773641 (DOT1L)
Enzymes [BR:myd01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.360  [histone H3]-lysine79 N-trimethyltransferase
     102773641 (DOT1L)
Chromosome and associated proteins [BR:myd03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     102773641 (DOT1L)
   HMT complexes
    Dot1-containing complex
     102773641 (DOT1L)
SSDB
Motif
Pfam: DOT1 HALZ
Other DBs
NCBI-GeneID: 102773641
NCBI-ProteinID: XP_015420888
Position
Un
AA seq 1730 aa
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVP
ESKAAVPADTSVDSGAEEEKAATTAIKKPSPSKARKKKLNKKGRKLAGRKRGRPKKMSTA
NPERKPKKNPTALDLLHAQTVSQTATPSPQDSYKSPHSPFYQLPPSVQRHPPEQLLLAPT
PPALQKLLESFKIQYLQFLAYTKTPQYKASLQQLLDQEKEKNARLLGAAQQLFGHCQAQK
EEIKKLFQQKLDELGVKALTYSDLIQAQKEISAHNQQLREQTEQLEKDNRELRSQSLQLL
KARCEELKLDWSTLSLENLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDDAVSLHLRGKGGLGRELEAEPSRLHLELDCSKFSLPHFSSMSPELSMNGHAAGY
ELCNTLSRPSSKQNTPQYLASPLDQEVVPCTPSHGGRPRLEKLSGLALPDYTRLSPAKLV
LRRHLSQDHTASGKTPAGELHPRTEHAKENGLPYQSPGLANGIKLSPQDPRPSSPVALQM
TGEKGSEKGLKERAYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPNRAEKRSTP
SPVPQTRESSSTLEKQMGANAHGAGSNAAGSKSLTLAPTGFYAGSVAISGALAGSPAPLA
PGVEPPVFDESSSSGSLFTTMGSRSSTPQHPQLLVQPRNSGPASPTHQLCVSPRLSAAQG
PLPDASKGDLPSEVGFSDPESEAKRRIIFTLSAAASSTRQSPSNKHSPLPGGARGDSSQN
HGQDSRKRGRRKRASAGTPNLSSGVSPKRRALPSVAGLFTQSSGSPLNLNSMVNNINQPL
EITAISSPESSLKSSPVPYQDNDQPPVLKKEKPLTQTNGAHYSPLTSDEEPGSEDEQGST
RIERKIATISLESKSPPKTLENGGSLVGRKPMPSSEPINSSKWKSTFSPIADLGLAKATD
SPLQASSTLSQNSLFAFRPTLEELSSVDAKLATHPRKSFPGALSGPGGLSPISNPPNGFA
FSGSLAADLSLHSFSDGASLSHKAPEVAGLGAPLSFSAPRGKESSTEPGPFVNKRQLDGL
GGPKGEGVKGREGEVSLPVCTPSDKASSHGKVGKGRDREPDFKNGHNLFISAAAVPPGGL
LSGPGLTTAASSASGTAPSSQTHRPFLGTFAPGPQFALGPMSLQANLGSSVLQSLFSSVP
AAAGLVHVSSAATRLTNSHAMGSFSSGVAGGAVGGIFNHTVPSASTHPFGASFGSGAXXX
XXXXNLTPMQAVASTPASSFQALSSVETRQPPPQPPLPLGRPPAGPPALHAPPPPPNATL
PPAPALLPANSEPVLLQNLAPLPANQAFLPASSAASLPPANASLSIKLASLPHKVSRPSF
MVHHQPLPGLALAQASPMIPQASSTGPSAVWVSLGMPPPYAARLAGVKPR
NT seq 5193 nt   +upstreamnt  +downstreamnt
atgggggagaagctggagctgaggctcaagtcgcccgtgggggccgagcccgccgtctat
ccgtggccgctgccggtctacgacaaacaccacgatgctgctcatgaaatcatcgagacc
atccgatgggtctgtgaggaaatcccagacctcaagctcgctatggagaattatgtccta
atcgactacgacaccaaaagcttcgaaagcatgcagaggctctgtgataagtacaaccgg
gccatcgacagcatccaccagctgtggaagggaaccacgcagcccatgaagctgaataca
cggccatccaatgggctcctgcggcacatcctgcagcaggtttacaaccactcagtgaca
gaccctgagaagctcaacaactacgagcccttctccccagaggtatatggggagacctcc
tttgacctggtcgcacagatgattgatgagatcaagatgaccgaggacgacctgtttgtg
gacctgggaagtggagtgggccaggttgtgctgcaagtcgccgcggccaccaactgcaaa
catcactacggagtcgagaaagcggacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaaaga
ggtgatttcctctcggaggagtggagagagcggatcgccaacacaagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgatttgcaaacatg
aaggaaggtggcagaattgtgtcctcgaagccctttgcacctctgaacttcagaataaac
agtagaaacttgagtgacatcggcaccatcatgcgcgtcgtggagctctcgcccctgaag
ggctcagtgtcgtggacggggaagcccgtctcctactacctgcacaccatcgaccgcacc
atacttgaaaactatttttctagtctgaaaaatccaaaactcagggaggaacaagaggca
gctaggcgccggcagcagcgagaaaacaagagtaatacaaccacccccacgaaggtgcct
gagagcaaggcggctgtgcctgcggacacctctgtggattctggtgctgaggaagagaaa
gcagcgaccaccgctatcaagaagccatccccctccaaagcacggaagaagaagctgaac
aagaagggccggaagctggctggacggaagcgcggacgtcccaagaagatgagcactgcg
aaccctgagcgtaagcccaagaagaaccctactgcactggacctcctgcacgcccagact
gtgtcccagacggcgacgccctcaccacaagattcatacaagtcacctcacagcccattt
tatcagctacctcccagcgtgcagcggcacccccctgaacagctgttgctggcacccacc
ccgcctgcactgcagaagctgctagagtccttcaagattcagtacctgcagttcctggca
tacacgaagacccctcagtacaaggccagcctgcagcagctgctggaccaggagaaggag
aagaatgcccgattgctgggtgccgcacagcagctgttcggtcactgccaggcccagaaa
gaagaaataaagaagctttttcagcagaaactggatgagttgggagtgaaggcgctgacc
tacagtgacctgatccaagctcagaaagagatctcagctcacaaccagcagctgcgagag
cagacggagcagctggagaaggacaacagggagctgagaagccagagcctgcagctgctg
aaggctcggtgtgaggagctgaagttggactggtccacactgtccctggagaacctgcta
aaggagaagcaggccctgaagagccagatctctgagaaacagaggcactgcctggagctg
cagataagcatcgtggagctggaaaagagccagcggcagcaggagctcctgcaactcaag
tcctgcgtgccacctgatgatgctgtgtccctgcacctacgagggaaaggtggcctgggc
cgagaactggaggcggaacccagccggctgcaccttgaactggactgctccaaattctcc
ctgccccacttcagtagcatgagcccggagctctccatgaatggccacgcggccggctat
gagctctgcaacacactgagtcggccctcgtccaagcagaacaccccccagtacctggcc
tctccactggaccaggaggtggtgccatgtactcccagccacggcggccggccccggctc
gagaagctatctggcttggccttgccagactacaccaggctctccccggccaagctggtg
ctgagacgccacctgagccaggaccacactgccagtggcaagacacctgctggtgagcta
cacccacgaactgagcacgccaaggagaatggccttccataccagagcccgggcctcgcc
aatggcatcaagctgagccctcaggacccacggccctcatcccctgtggccttacagatg
acgggagaaaaaggcagtgagaagggtctgaaggagcgcgcctatgccagcagtggggag
gccatcaccagcctacccgtcagcattccactcagcactgtgcagcccagcaagctgccc
gtcagcatccccctggccagcgtggtgttacccaaccgtgccgagaagagaagcaccccc
agtcctgtgcctcagacccgagagtcctcgtccacacttgaaaagcagatgggtgctaac
gcccatggtgctgggagcaacgctgctgggagcaaaagcctcaccctggcgcccacaggc
ttctatgcaggctcagtcgccatcagtggggccctggcaggcagcccggccccactcgct
cctggagttgagccccctgtcttcgatgagtcctccagctcggggagcctcttcaccacc
atgggctcccgcagctccaccccacagcatcctcaactgctagtgcaaccccggaactcc
ggtccagcctcgcccacgcaccagctctgcgtcagcccccgactcagcgctgcccagggc
ccactccctgatgcgagcaaaggggaccttccctctgaggttggcttctcagatccagag
agcgaggccaagaggaggatcatcttcaccctctcagctgctgccagcagcaccaggcag
tcaccttccaacaagcacagccctctgcctgggggtgctcgtggagacagcagccagaac
catgggcaggacagtcgaaagcggggcaggaggaagcgggcatcggcggggacccccaat
ctgagctcaggcgtgtcccccaagcgccgggccttgccatccgtcgccggcctcttcact
cagtcttcagggtctccgctcaacctgaactctatggtcaacaacattaaccaacctttg
gaaatcacagccatctcgtcccctgagagctccctgaagagctcccctgtaccttaccag
gacaacgaccagccacccgtgctcaagaaagagaagcccctgacccagaccaatggagcc
cactactccccactgacctcagatgaggagccgggctctgaggacgagcaaggcagcacc
agaattgagagaaaaattgcaactatctccttagaaagcaaatctcctccgaaaaccttg
gaaaatggtggcagcctggtaggaaggaagccgatgccctccagcgagcccatcaacagc
agcaagtggaagtccaccttctcacccatcgctgaccttggcctggccaaggctactgac
agcccgctacaggccagctccactctgagccagaactccctgttcgcttttcggcccacc
ctagaggagctcagctcagttgatgccaagctggccacccaccccaggaagagctttccg
ggtgcactgtcggggcctggcgggctgagtcccatcagcaacccccccaacggctttgcc
ttcagcgggagcctggctgccgacctcagtttacacagtttcagtgatggtgcttctctc
tcccacaaggcccctgaggtggccggcctgggcgcccccctgagcttttccgccccgagg
ggtaaggagagcagcacggagcctggcccctttgtgaacaagaggcagctggatggactg
ggtggcccgaagggtgagggggtcaagggcagggagggagaagtcagcttgcccgtgtgc
acaccctcagacaaggcctcatcacatggcaaggtgggcaagggccgggaccgcgagcct
gatttcaaaaatggccacaatctcttcatttctgccgctgccgtgcctcctgggggcctc
ctcagcgggccaggcctcaccacagcagcgtcctcagcaagcggcacagccccctcctcc
cagacacaccggcccttcctgggcacttttgcacctggcccacagtttgccttgggcccc
atgtccctgcaggccaacttaggctcatctgtgctgcagtccttgttcagctctgtgccg
gctgctgctggcctagtgcacgtctcatccgctgcaaccagactgaccaactctcatgcc
atgggcagcttttcctccggtgtggcaggtggtgcagttggaggtatctttaaccacacg
gtgccttccgcctccactcatccgtttggagccagtttcggcagcggggcnnnnnnnnnn
nnnnnnnnnnnnaacttaaccccgatgcaggcggtggccagtacccccgcctcttccttt
caggccctgtcctctgtggagaccaggcagcccccaccccagcctcctctgcccctgggt
cggccccctgcggggccaccagcacttcacgcgcccccccctcctcctaacgctaccttg
cctcctgctcctgcactgctccctgctaactctgagcctgtgctcctgcagaatcttgcg
cccctcccggctaaccaagctttcttacctgcctcctctgccgcctctctgcctcctgct
aacgcctctctgtctatcaagctcgcctccctcccacacaaggtctcccgcccctccttc
atggtgcaccaccagcccctgcctggactggctctggcccaggcctcacccatgatccca
caggccagctccacggggccatccgccgtgtgggtttcccttggcatgccgcctccttat
gccgcgcgccttgcgggggttaagccgcgataa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (25)   

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