KEGG   Mycobacterium sp. EPa45: AB431_27445
Entry
AB431_27445       CDS       T03960                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
mye  Mycobacterium sp. EPa45
Pathway
mye00290  Valine, leucine and isoleucine biosynthesis
mye00620  Pyruvate metabolism
mye01100  Metabolic pathways
mye01110  Biosynthesis of secondary metabolites
mye01210  2-Oxocarboxylic acid metabolism
mye01230  Biosynthesis of amino acids
Module
mye_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:mye00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    AB431_27445
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    AB431_27445
Enzymes [BR:mye01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     AB431_27445
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: AKK29799
UniProt: A0A0G3ISI1
Position
5769363..5771201
AA seq 612 aa
MTTHSFESVDAYVSARTITTPAGPPREGQPAWNTQRSSSMPVNRYRPFAAEIPGGAPESP
FARTWPDKVIEHAPLWCAVDLRDGNQALIDPMSPARKRRMFELLVNMGYKEIEVGFPSAS
QTDFDFVREIIDQGAIPDDVTIQVLTQCRPELITRTFEACAGAPRAIVHFYNSTSILQRR
VVFRADREAVKKIATDGARLCVEEAAKYPATQWRFEYSPESYTGTELEYAVDVCNAVAEI
VQPTPDVPLIVNLPATVEMATPNVYADSIEWMNRHLAPRDSIILSLHPHNDRGTAVAAAE
LGYQAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQL
PVHERHPYGGDLVYTAFSGSHQDAINKGLDAMKVAADEADSDVDDILWQVPYLPIDPKDV
GRTYEAVIRVNSQSGKGGVAYIMKADHGLVLPRRLQIEFSQAIQAITDGEGGEVSPKEMW
DAFADEYLSPVRPLERIRQKVVGSEVDGGTDVIEAVVKINGTETQINGRGNGPLAAFVDA
LGTVGFDVSVLDYSEHAMSAGEEAAAAAYVEASIGGRTVWGVGIATSITTASLRAVVSAV
NRAARIGAIPTA
NT seq 1839 nt   +upstreamnt  +downstreamnt
gtgaccacgcattcttttgaatctgtagacgcctacgtctctgcccgcactatcaccacc
cccgccggcccgccacgcgaaggccagcccgcctggaacacccagcggagttcctcgatg
ccggtcaaccggtaccgcccgtttgccgctgagatccccggaggagcgcccgaatccccc
ttcgcccggacctggccggacaaggtcatcgaacacgcaccactgtggtgtgcggtcgac
ctgcgcgacggcaaccaggccctgatcgacccgatgagcccggctcgcaaacgccggatg
ttcgagctgctggtcaacatgggctacaaggagatcgaggtcggcttcccgtcggccagc
cagaccgacttcgacttcgtccgcgagatcatcgaccagggcgcgatccccgatgacgtc
accatccaggtgctgacgcagtgtcgccccgaattgatcacccgcacgttcgaagcgtgt
gccggtgcgccgcgtgcgatcgtgcacttctacaactccacctcgatcctgcagcgccgc
gtcgtgttccgtgccgaccgcgaggcggtcaagaagatcgccaccgacggcgcccggctg
tgtgtcgaggaggcggccaaataccccgccacccagtggcggttcgagtactctcccgag
tcctacaccggcaccgagctggagtacgccgtcgacgtgtgcaacgccgtcgctgagatc
gtgcagccgaccccggatgtgccgctgatcgtgaacctgccggcgaccgtggagatggcc
accccgaacgtttatgccgattcgatcgagtggatgaatcgccatctggcaccgcgggat
tcgataatcttgagcttgcatccgcacaatgaccgcggaactgccgtcgccgcagccgaa
ttgggttatcaggccggtgcggatcgcatcgagggttgcctgttcggaaatggtgagcgc
accggcaacgtctgcctggtgacgctggggctgaacctgttctcccgcggtgtggatccg
cagatcgatttctcgaatatcgacgagatccgccgcaccgtcgagtactgcaaccagctg
cccgtgcacgagcgccacccctacggcggcgacctggtgtacaccgcgttctccggcagc
catcaggacgccatcaacaagggcttggacgcgatgaaagtcgctgccgacgaggcggat
tcggatgtcgatgacatcctgtggcaggtgccgtatctgccgatcgaccccaaagacgtc
ggccgcacgtatgaggcggtgatccgggtcaattcgcagtccggcaagggcggcgtggcc
tacatcatgaaggccgatcacggactggtgctgccgcgccggttgcagatcgagttctcc
caagccattcaggcgatcaccgacggtgagggcggcgaggtgtcaccgaaggagatgtgg
gacgccttcgccgacgaatacctgtcgccggtgcgcccgctggaacgcatccgccagaag
gtggtcgggtccgaggtcgatggcggcaccgacgtcatcgaggccgtcgtcaagatcaac
gggaccgagacacagatcaacggccggggcaacggtccgctggccgcgttcgtcgacgcc
ctgggcaccgtcggcttcgatgtgagcgtgctggactactccgaacacgcgatgtccgcc
ggtgaggaggccgctgcggcggcctacgtcgaggcgtccatcggcgggcgcaccgtgtgg
ggtgtcggcatcgcgacgtcgatcaccacggcgtcgctgcgggcggtggtctcggcggtg
aaccgggccgcgcggatcggcgccatccctacggcgtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (23)   

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