KEGG   Maylandia zebra (zebra mbuna): 101464277
Entry
101464277         CDS       T02814                                 
Symbol
arhgef12
Name
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X1
  KO
K07532  Rho guanine nucleotide exchange factor 12
Organism
mze  Maylandia zebra (zebra mbuna)
Pathway
mze04270  Vascular smooth muscle contraction
mze04625  C-type lectin receptor signaling pathway
mze04810  Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:mze00001]
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101464277 (arhgef12)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    101464277 (arhgef12)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    101464277 (arhgef12)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mze04131]
    101464277 (arhgef12)
Membrane trafficking [BR:mze04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    101464277 (arhgef12)
SSDB
Motif
Pfam: RGS-like PH_16 RhoGEF PDZ PDZ_6 PDZ_2 PH_13 PH
Other DBs
NCBI-GeneID: 101464277
NCBI-ProteinID: XP_004543798
UniProt: A0A3P9CFY4
Position
LG14:complement(18542401..18586771)
AA seq 1418 aa
MSDTQPSFTDRFPKKANRTSSILSKDHPPDKKPKSERNSLPSNEFDPTEALVVQKSGSSS
VLPEGKPESCGLVQRCVIIQKDENGFGLTVSGDNPVFVQLVKEDGAAMRAGVQTGDRIIK
VNGTHVAHSNHTEVVKLIKSGSYVALTVLGRPPGLAQIPLPEAEPDMSLSSPNSPAPRRP
CSPQDSILPIQQPWDEKADILEAMKEEYSRNPSPKLLKDIQEAEKHIPQLQGQLPKAIGT
TQEIVPSDDADEDAFVPKGENNADLFWTRTPISRIFGPSSPDSQCPREFSCPSPKTTPRN
SYNSFHSPETEDTTDLDALSPTTVSSPSSSRLVSQIIGAEDDYFDSDQEQTNGQCNSFNS
IELLKSRPAHLAAFLYHVISQFDPAPVLCYLYADLYKQTNSKETRRVFMGLHNFFIDRGA
NLKVGVPESVSADLDRRRTELIPEEINRQHVQTLQDSLLPDIQKNLEDFRQKRSMGLTVA
EAELGRLDQERVRDRGTLERERSYAENIIAKIDDILVTTQLTEEEKCTTMQYVIYTYMKH
LGVRVKEPRSLESKRLRISFLPMIKRGNKTEKEREEKVKKVPKNNKFNIRVPQRRPSRIE
SSGGTTQEGRPRPQKQMSQPALSTSDYKESSRLKGSQSSEGPELIHSMSVNSSSPISATY
SSDTSRDADMGGTPIFGPCRVSEILPSDSLDGLPYSASQFDPLYNLDQLPEDDRESDRTH
EGTPKALRRLEGLGAADIQSEDDQGTDSECDPPNWQHLVRPEVLAGLRPHEIKRQEVIHE
LFYTERAHVRMLKVLDNVFYQKLTKDSILPPADIKNIFSNLEEVLQLHVNISDQMAAVRK
RNDSSVIDQIGDDLLSWFSGGEEEKIKQAVGTFCSNQPFALELIKTKQKKDSRFTSFILE
AESNRQCRRLQLKDIIPVEMLRLTKYPLLLDNIVKYTDNAEEKEKVKQAADCCRKILSHV
NQAVKESEDKQRLEDYQRRLDLSSLKQTDNPMILELKNLDLTKKTMVHEGPLSWKVNKDK
TIELYTLLLEDILVLLQKQDERLILKCHSKNLSGTADTKHIFSPIIKLNTVLVRSVATDN
KSFFVLSMSENGAQIYELMAPTVSDQRTWQRLITQRAEAMKVKPHSVIPLPQTVGERDGV
EIITTGVSRLSRDTDRTSTGSTQSTDKESSPVCRSALQTSLPGSNPFEGVKTEEEKEEEE
EGFVDPELSYPVAEDCRGASFSMFPSRADEALKTLAALKHVLVTQLMSQEAAEQTKRSTG
ARLLRTTSLRTPIDSRARVTVHNGSEKTGSQTDDLAQDLGSGDTGFFDSTDDYAAYLVLE
GYGGPGESSTDDDILATTTGKQLSTSQGCAADSGINLRFSSTSQAGSLSSFSRQVLSHLR
NLQANLNYLKEVEAKYNSLIQQRPERSAADTHGNKDKR
NT seq 4257 nt   +upstreamnt  +downstreamnt
atgagtgacacacagcccagcttcactgacaggtttcccaagaaagcaaacagaaccagc
agtattctcagtaaagaccaccccccagacaagaaacccaaaagtgaaagaaattccctt
ccctccaatgagtttgaccctacagaagctctggtggtgcagaagagtggcagcagcagt
gtgctaccagaggggaagcctgagtcctgtggtctggtccagcgatgtgtaataatccag
aaagatgaaaatggctttgggctcactgtcagtggtgacaatccagtgtttgtgcagctt
gtcaaagaagatggggctgcgatgcgagcaggtgttcagacaggagacaggatcatcaag
gttaatgggacccatgttgcacattctaaccacacagaagtggtgaaacttattaaatcg
ggctcctatgtggccctcacagtgctgggccggccccccgggcttgcccagatacctttg
cccgaagcagagccagacatgagcttatcctctccaaactctccagcaccacggcgcccc
tgcagtcctcaggacagcatcttacctattcaacaaccatgggatgagaaagctgacatc
ttggaggccatgaaggaggagtacagcagaaacccctcccctaaactactgaaagacatc
caggaagctgaaaaacacattcctcagctgcagggtcagctccccaaggccattgggaca
acacaggagattgttccaagtgatgatgcagatgaagatgcatttgtccccaagggagaa
aacaatgcagacctgttctggaccaggacccctatatctcgcatatttgggccgtcatct
ccagacagccagtgtccaagagagttctcctgccccagcccaaagaccacacccaggaac
agctacaactccttccactccccagagacagaggacaccactgatctggacgccctttcc
cctaccacagtcagcagtccctcctcgtctcgcctggtttcgcagatcattggagctgag
gatgactattttgattcagaccaagagcagacaaacggccagtgtaacagctttaatagt
attgagctgctcaagtctcgccctgcccacctcgcagcctttctgtatcatgtcatctct
cagttcgaccctgctcccgtgctgtgctacctctatgctgacctctacaagcagaccaac
tccaaagagaccagacgggtgttcatgggccttcacaatttcttcattgaccggggagca
aatttaaaagttggtgttcctgaatctgtctccgctgatcttgatcggcggcggacagaa
ctgatcccagaggaaataaacagacaacatgttcaaacactgcaggactctctgctccct
gatattcagaagaatcttgaagatttcaggcagaagcggagtatgggcctaacagtggct
gaagcagagctgggcagactggaccaagagagagtcagagaccgcggcactctcgagcgg
gaacgctcatatgctgaaaacatcatcgcgaaaatagacgatatcctggtaactactcaa
ctcacagaggaagagaaatgcactacaatgcagtatgttatatatacgtacatgaagcac
cttggtgtgagggtcaaggaacctcgcagcctggagtccaaacggcttcggatcagcttt
cttcccatgattaagcgaggcaacaagacagaaaaggaaagggaagagaaagtgaaaaag
gttcccaagaataataaatttaatattcgtgtacctcagcggcggcccagccgcatcgaa
tcgtcagggggtacgacccaggagggacgaccacggcctcagaaacagatgtctcaacct
gcactgtctacaagtgattataaagaatctagtcgtctcaaaggcagccaatcaagcgag
ggccctgaacttatacactccatgtctgtcaactcatcatctccaattagcgccacctac
agctctgacaccagcagagacgctgatatgggtgggactccaatatttggcccctgcagg
gtgagtgaaatccttccatcggactctctggacgggttgccatactctgcttcgcagttt
gaccctctatataacctggaccaactgccagaggatgacagagaaagtgacagaactcac
gagggaacaccaaaagctttaagaaggcttgagggactcggtgctgctgatatccagagc
gaggatgaccagggaacagattctgagtgcgatcccccaaactggcagcatctggtgcgt
ccagaggttctagccggtctcaggcctcatgaaatcaagagacaggaagttatccacgag
ctgttttacacagagcgtgcacatgtacggatgctgaaggttttggacaacgttttctac
cagaagctcaccaaagactccatcctgcctcctgctgacatcaagaatattttctccaat
ctggaagaggttctgcagctgcatgttaacatatcagatcaaatggctgccgttcggaag
agaaatgactcttcagtaattgatcagataggagacgacttgctttcctggttcagcggt
ggagaggaagagaagatcaagcaggcggtggggacgttctgcagtaaccagccttttgct
ctggagctcataaagaccaaacagaagaaggactcgaggttcacttcattcattctggag
gcagagagtaacaggcagtgtcgccgactgcaactcaaggacatcattcctgtggagatg
ctgcggctcaccaagtaccctctgctgctcgacaacattgtcaagtacacagacaatgca
gaggagaaggagaaagttaagcaggcagcagactgctgcagaaagatcctcagtcacgtc
aaccaggctgtgaaggaatctgaggacaaacagaggttggaggactatcagagacgattg
gacctctcttctctaaagcagacagacaacccaatgatcctggagctaaagaacttggat
ctgacaaagaaaacgatggtgcacgagggtccactgtcatggaaagtgaacaaggacaaa
actatcgagctctatacactcctcctggaggacatcctggttctcctacagaaacaagat
gagcgtctgatactgaagtgtcacagcaaaaacctgtcgggcactgcagataccaaacat
atcttcagccctatcatcaaactcaacacggtgctggtgcgctcagtggccacagacaac
aagtccttctttgttctttcgatgtcggaaaacggagcccaaatctacgagctaatggcg
cccactgtctcagatcagagaacgtggcagcgtctaatcacgcagagagctgaagccatg
aaagttaagcctcacagcgtcataccattacctcagaccgttggggagagagacggcgtg
gagatcattacaacgggagtttccaggttgagtagagacacggaccgcacatccactggc
agcacccagtccacagataaggaaagcagtccagtctgtagaagcgcactgcagacttcg
ctacctggcagtaatccgtttgagggagtgaagactgaggaggagaaggaggaggaagaa
gaaggctttgtggacccagaactttcttatccagtggccgaggattgcagaggagcctcg
tttagcatgttcccctcgagggcagacgaagcactgaaaacactggcagcattaaagcac
gtgttagtgacccagcttatgtcccaggaagctgcagagcaaactaaacgctccacaggg
gctcgcctcctcaggaccacctctctgcgcacccccatagacagccgtgcacgagtgacg
gtccacaacggctcagagaaaaccggctcccagacagacgacctggctcaggacctgggt
tcaggagacaccggcttctttgactcgactgatgactatgctgcgtatttagtcctggag
ggttacggtggcccaggggagagcagcacagacgatgacatcttggcaacaaccacaggg
aagcagctgagcacttcccaaggctgcgctgctgactcgggcatcaatttgagattttct
tcaacatcacaggccggcagcctctcctctttcagcagacaggtcctctctcaccttcga
aatcttcaggccaacctcaattatctgaaggaggttgaggccaagtacaacagtctaata
cagcaaaggccagagagatcagcagcagacacgcatggaaataaagataagagatag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (29)   
   KEGG ORTHOLOGY (1)   
   RefGene (25)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (8)   
   RefSeq(nuc) (2)   
   GenBank (3)   
   EMBL (3)   
Protein domain (8)   
   Pfam (8)   
All databases (54)   

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