KEGG T04867: NECAME

Necator americanus (New World hookworm): NECAME_01399

Entry

NECAME_01399      CDS       T04867

Name

(RefSeq) 3'5'-cyclic nucleotide phosphodiesterase

K18438

cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]

Organism

nai Necator americanus (New World hookworm)

Pathway

nai00230

Purine metabolism

nai01100

Metabolic pathways

Brite

KEGG Orthology (KO) [BR:nai00001]
09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    NECAME_01399
Enzymes [BR:nai01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     NECAME_01399
    3.1.4.35  3',5'-cyclic-GMP phosphodiesterase
     NECAME_01399

SSDB

Motif

Pfam:

PDEase_I GAF GAF_2 GAF_3 SpoVT_C

Other DBs

NCBI-GeneID:

25341441

NCBI-ProteinID:

XP_013307737

UniProt:

W2TTV3

Position

Unknown

AA seq 716 aa
MARISANRIVYLICITLQDVFRFQSEDLESRRRIILDHGDDQVRILYELAQCCAQIANTD
LCELFVQNEEGVFLVYKEMGEKPQIKCRKVKRARRNPMHLQKLIDIDEGNIGEIHFNTPV
SERDRQIINVICTWAAASLHYAQVAAQLERTGSSSEIFARQRRLNQFLLDVAKSIFQDIV
SMDTVIIKVMNFAAKLVDADRASLFLVDNKNHELYARIFDIGRGSEELEKINKEGHKEIR
FSMNRGIAGHVASTGEGLNIEDAYEDSRFNPEVDSKTGYTTKTILCMPIFIRGSVIGVVQ
MVNKHEGVFTKADEDSFEVFAVYCGLALHHAKLYDKIRRSEQKYRVALEVLAYHSVCNKD
EVAKLQKMEIRDRVEELETFEFNYLRMSELEKPLYAIAMFKTLFQEQFRYDRDDLIRFVL
TVRKNYRRVAYHNWAHGWSVAHAMFVLLMHTSRDIFNTHEALALYVSCLCHDLDHRGKNN
AYMKSMMTPLASIYTTSVMEHHHFNQTVTILQQDGHNILKTMNSSDYKQALSLIKHCILA
TDLALFFTNKAELNKILDSGKYDIHDEHHRRLTQAILMTGCDLIASAKPWYIQTETVKVI
FEEFYEQGDAERQNGREPIAMMDRNKAHELPQMQVTLLSFLLLAQYSNFLSTILMVGFMR
GICLPCYELVAKVIPDAAFLRDQCEYNAKKWEELAAEQAELNKQKTEETTIEKGKE

NT seq 2151 nt +upstreamnt +downstreamnt
atggcaaggataagcgcgaatagaatagtatatctaatatgtataactctacaagatgtt
ttccgttttcagtcagaagatctcgagtccagacgccgtattatcctggaccacggagac
gatcaggtccggattctatatgaattggcgcaatgttgtgctcaaatcgccaacaccgac
ctctgcgaattatttgtccagaacgaggagggcgtttttcttgtctacaaggaaatgggc
gagaagccacaaattaaatgtcgtaaagtgaaacgcgctcgtagaaatcctatgcatcta
cagaagttgatcgatatcgacgaaggaaatattggagaaatccacttcaatacgcctgtc
tcagaacgggaccgacaaatcatcaatgtgatttgtacgtgggctgcagcttcactgcac
tatgcgcaggtagctgctcaacttgagcgaacaggtagcagctcggaaatatttgctcga
caacgacgtcttaaccagtttctccttgacgtcgcgaaaagtatcttccaggatatcgtc
tccatggacacggtgataatcaaggttatgaacttcgctgcaaaactggtcgatgcggac
agagcatcgttgtttcttgttgacaacaaaaatcatgagctctacgccagaatattcgac
attggtagaggaagcgaggaactggagaagattaacaaggaaggacataaggaaattcgg
ttcagcatgaatcgaggaatagcagggcacgtggcttcaactggcgagggactcaatata
gaggatgcctacgaggatagcaggtttaatcctgaagtggactcaaagactggatacact
acaaaaactattctttgtatgccgatattcattcgtggcagtgtaattggcgtcgtgcaa
atggtgaacaaacacgagggtgtattcacgaaagccgacgaggacagttttgaggtgttc
gctgtatattgcggattagcactgcaccacgctaaactctacgataaaatcagaagatct
gaacaaaaatatcgcgtcgctttggaagttctcgcttatcatagcgtgtgtaataaagat
gaggtggctaagctacaaaagatggagatcagagaccgagtggaagagcttgagacgttt
gaattcaactatttgcgtatgtcggagctggagaagccactgtacgcaatcgctatgttc
aaaacattattccaggagcaattccgttatgatcgcgacgacttgattcgttttgttctc
actgtgaggaagaactatcgacgagtggcgtatcataactgggcgcatggatggtccgta
gctcatgccatgtttgttttgttaatgcatacatctcgtgacatcttcaacactcacgag
gcactagcgctgtatgtgtcgtgtctgtgtcatgacttggatcatcgtggaaaaaacaac
gcctacatgaaatcaatgatgacaccgttggctagtatttatacgacatctgtaatggag
catcatcacttcaatcaaacggtgaccatccttcaacaagatggtcataatatcctgaaa
acaatgaactcatccgactataaacaagcgttgtccctcatcaagcactgcatcctcgcc
acggatctcgcgctattcttcactaacaaagcagaacttaacaaaatcctcgacagcggc
aaatacgatatccatgacgagcatcaccggagactgactcaagcgattttaatgaccggt
tgtgacctgatcgcttccgctaagccatggtacattcagacggagaccgtgaaggtcata
ttcgaggagttctacgagcagggtgacgctgaacgacagaacggacgtgaaccgatcgca
atgatggatcgtaacaaggcacatgaacttccccagatgcaggttacgcttctgtcattt
ttgttgcttgcgcagtactcgaatttccttagcaccattttaatggtaggatttatgcgt
ggtatttgtctgccatgttatgaactagtcgctaaagtgattccggatgcagcgtttctg
agggatcagtgcgagtacaacgctaaaaaatgggaggagttggcagccgaacaagcggaa
ttaaacaaacaaaaaactgaagagacaacaatcgagaaaggaaaggagtga

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