KEGG   Neurospora crassa: NCU03139Help
Entry
NCU03139          CDS       T01034                                 

Definition
histidine biosynthesis trifunctional protein
Orthology
K14152  
phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:3.6.1.31 3.5.4.19 1.1.1.23]
Organism
ncr  Neurospora crassa
Pathway
Histidine metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Biosynthesis of amino acids
Module
Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:ncr00001]
 Metabolism
  Overview
   01230 Biosynthesis of amino acids
    NCU03139
  Amino acid metabolism
   00340 Histidine metabolism
    NCU03139
Enzymes [BR:ncr01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.23  histidinol dehydrogenase
     NCU03139
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.19  phosphoribosyl-AMP cyclohydrolase
     NCU03139
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.31  phosphoribosyl-ATP diphosphatase
     NCU03139
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
I
AA seq 870 aa AA seqDB search
METTLPLPFLVGVSVPPGLNDIKEGLSREEVSCLGCVFFEVKPQTLEKILRFLKRHNVEF
EPYFDVTALESIDDIITLLDAGARKVFVKTEQLADLSAYGSRVAPIVTGSSAALLSSATE
SGLLLSGFDQTASEAAQFLEEARDKKITPFFIKPVPGADLEQFIQVAAKANAIPILPSTG
LTTKKDEAGKLAISTILSSVWKSDRPDGLLPTVVVDEHDTALGLVYSSAESVNEALRTQT
GVYQSRKRGLWYKGATSGDTQELVRISLDCDNDALKFVVKQKGRFCHLDQSGCFGQLKGL
PKLEQTLISRKQSAPEGSYTARLFSDEKLVRAKIMEEAEELCTAQTPQEIAFEAADLFYF
ALTRAVAAGVTLADIERSLDAKSWKVKRRTGDAKGKWAEKEGIKPAASALAATSAPVTKE
AAQETTPEKITMRRFDASKVSTEELDAALKRPAQKSSDAIYKIIVPIIEDVRKNGDKAVL
SYTHKFEKATSLTSPVLKAPFPKELMQLPEETIAAIDVSFENIRKFHAAQKEEKPLQVET
MPGVVCSRFSRPIEAVGCYIPGGTAVLPSTALMLGVPAMVAGCNKIVFASPPRADGTITP
EIVYVAHKVGAESIVLAGGAQAVAAMAYGTESITKVDKILGPGNQFVTAAKMFVSNDTNA
AVGIDMPAGPSEVLVIADKDANPAFVASDLLSQAEHGVDSQVILIAIDLDEEHLQAIEDE
VHRQATELPRVQIVRGSIAHSITVQVKTVEEAMELSNKYAPEHLILQIKEAEKAVDLVMN
AGSVFIGAWTPESVGDYSAGVNHSLPTYGFAKQYSGVNLASFVKHITSSNLTAEGLKNVG
QAVMQLAKVEELEAHRRAVSIRLEHMSKSN
NT seq 2613 nt NT seq  +upstreamnt  +downstreamnt
atggagacaacacttcccctccccttcctcgtcggtgtcagtgttcctcccggactgaat
gacatcaaggagggcctcagccgggaggaagtctcgtgtcttggctgcgtcttcttcgag
gtcaagccccagacccttgagaaaatcctgcgattcctcaagcgtcacaatgtcgaattt
gagccctacttcgatgtaacagccctcgagtctatcgatgatattatcactcttctggac
gccggcgcccgcaaggtgtttgtcaagaccgagcagttggccgacctctccgcatatggc
tcccgcgttgcccccattgtcactggaagcagcgctgctttgctttcctccgccaccgag
agcggccttttgctctccggcttcgatcagactgcctccgaggctgcacagtttctggag
gaggccagagacaagaaaattacccccttcttcatcaagcccgttcctggggccgatctc
gaacagttcatccaggtcgccgccaaggctaacgccatccccatcctgccatccactggc
ttgacaacaaagaaggacgaggccggcaagcttgccatctccaccatcctctcgagcgtc
tggaagtctgaccgtcccgatggtcttctccccaccgttgtcgttgatgagcacgacact
gctctgggtctggtctacagcagtgccgagagtgtgaacgaggccctcaggacacagact
ggtgtctatcagagccggaagcgcggtctctggtacaagggtgctacttccggagacact
caggagctcgtccgcatctcgcttgactgcgataacgatgctctcaagtttgtcgtgaag
cagaagggtcgtttctgccacctcgatcagtccggctgctttggtcagctcaaaggcctt
cccaagctcgagcagactttgatttcgaggaaacagtctgcccccgagggctcctacact
gcccgtctcttctccgatgagaagctagtccgggccaagatcatggaggaggctgaggag
ctctgcaccgctcagaccccccaggaaatcgcctttgaggctgccgatctcttctacttt
gctcttaccagggccgttgctgccggcgttactcttgccgatatcgaaaggagccttgac
gccaagagctggaaggtcaagcgcaggactggagatgctaagggtaagtgggctgagaag
gagggcatcaagcctgcggcgtccgctctcgctgccacttcggcccctgtcaccaaggag
gccgcccaggagaccacccctgagaagatcaccatgagacgtttcgacgcctccaaggtc
tctaccgaggagctcgatgctgctctcaagcgtcctgcgcaaaagtcgtccgatgccatc
tacaagatcattgtccccatcatcgaggacgtccgcaagaacggcgacaaggctgttctg
tcgtacactcacaagttcgagaaggctacctctcttactagccccgtcctgaaggcgccc
ttccccaaggagcttatgcagctccctgaggagaccattgctgccatcgacgtgtccttc
gagaacatccgcaagttccacgccgcccagaaggaggagaagcccctccaggtcgagacc
atgcccggtgttgtctgcagccgtttctctcgtcccatcgaggccgtcggctgctacatc
cccggcggtaccgccgttctccccagcactgcccttatgctgggtgttcccgccatggtc
gccggctgcaacaagattgtgttcgcctctcctccccgcgccgacggaaccatcactccc
gagattgtctacgtcgctcacaaggttggcgccgagtccatcgtgcttgccggcggtgcc
caggccgtagctgccatggcctacggcaccgagagcatcaccaaggtcgacaagattctc
ggccccggtaaccagttcgtcactgctgccaagatgttcgtcagcaacgacaccaacgct
gccgttggtattgacatgcccgctggcccgtccgaggtgctggtcatcgctgacaaggac
gccaaccccgcgttcgttgcctcggatctcctgtcccaggctgagcacggcgttgacagt
caggtcatcctgatcgctattgacctcgacgaggagcatcttcaggctattgaggacgag
gttcaccgtcaggctacggagcttcctcgcgtccagattgtccgtggctccatcgcccac
tcgatcaccgtgcaggtcaagaccgtcgaggaggccatggagctcagcaacaagtacgct
cctgagcacttgatcctccagatcaaggaggccgagaaggctgtcgatcttgtcatgaac
gccggtagtgtcttcattggcgcctggactcctgagtccgttggcgattactctgctggt
gttaaccactcgctgcctacctatggctttgccaagcagtactctggcgtcaatctcgcc
tcgttcgtcaagcacattaccagctccaacttgactgccgagggtctcaaaaacgtcggc
caggctgtcatgcagttggctaaggttgaggagctcgaggctcacagaagggcggtcagc
atccgtcttgagcacatgagcaagagcaactaa

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