KEGG   Nothobranchius furzeri (turquoise killifish): 107393294
Entry
107393294         CDS       T05163                                 
Symbol
map2k2
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 2
  KO
K04369  mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
Organism
nfu  Nothobranchius furzeri (turquoise killifish)
Pathway
nfu04010  MAPK signaling pathway
nfu04012  ErbB signaling pathway
nfu04068  FoxO signaling pathway
nfu04140  Autophagy - animal
nfu04148  Efferocytosis
nfu04150  mTOR signaling pathway
nfu04210  Apoptosis
nfu04218  Cellular senescence
nfu04270  Vascular smooth muscle contraction
nfu04370  VEGF signaling pathway
nfu04371  Apelin signaling pathway
nfu04540  Gap junction
nfu04620  Toll-like receptor signaling pathway
nfu04810  Regulation of actin cytoskeleton
nfu04910  Insulin signaling pathway
nfu04912  GnRH signaling pathway
nfu04916  Melanogenesis
nfu05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:nfu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    107393294 (map2k2)
   04012 ErbB signaling pathway
    107393294 (map2k2)
   04370 VEGF signaling pathway
    107393294 (map2k2)
   04371 Apelin signaling pathway
    107393294 (map2k2)
   04068 FoxO signaling pathway
    107393294 (map2k2)
   04150 mTOR signaling pathway
    107393294 (map2k2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    107393294 (map2k2)
   04148 Efferocytosis
    107393294 (map2k2)
  09143 Cell growth and death
   04210 Apoptosis
    107393294 (map2k2)
   04218 Cellular senescence
    107393294 (map2k2)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    107393294 (map2k2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    107393294 (map2k2)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    107393294 (map2k2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    107393294 (map2k2)
   04912 GnRH signaling pathway
    107393294 (map2k2)
   04916 Melanogenesis
    107393294 (map2k2)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    107393294 (map2k2)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    107393294 (map2k2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:nfu01001]
    107393294 (map2k2)
Enzymes [BR:nfu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     107393294 (map2k2)
Protein kinases [BR:nfu01001]
 Serine/threonine kinases: STE group
  STE7 family
   107393294 (map2k2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Pkinase_fungal Kinase-like Haspin_kinase Seadorna_VP7 Kdo APH
Other DBs
NCBI-GeneID: 107393294
NCBI-ProteinID: XP_015827025
UniProt: A0A1A8UK24
Position
sgr17:29819092..29827517
AA seq 399 aa
MAPKRRPVPLNITPIGEGQATSNTIDAASEANLEALQKKLGELDLDEQQRKRLEAFLTQK
AQVGELKDEDFDPICELGAGNGGVVNKVRHKPSGLVMARKLIHLEIKPAIRNQIIRELQV
LHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEARRIPEEILGKVSIAVLRGL
AYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQG
THYSVQSDVWSMGLSLVELAIGRYPIPPPDAKELEAIFGRAIMDGAEGEAHSNTQRPRPP
GRPGSGHGMDSRPAMAIFELLDYIVNEPPPKLPHGVFTSDFQDFVTKCLIKNPAERADLK
MLMSHTFIKRSEVEEVDFAGWLCKTMGLNQPSTPTRGTE
NT seq 1200 nt   +upstreamnt  +downstreamnt
atggctcctaaaagaagacccgtgcctctcaacattacgcccattggggagggacaggcc
acctctaacaccattgatgctgcatcagaagccaacctggaggctctgcagaagaagctg
ggtgaactggacctcgatgagcagcaaagaaaacgtctagaagctttcctcacccagaaa
gcccaggtcggggagctgaaggatgaagattttgacccgatttgtgagttgggtgctgga
aacggaggagtggtcaacaaggttcgccacaaaccctcgggtttggtcatggctcgaaag
ttaatccacctggagatcaagcctgccatcagaaaccagataatccgagagctgcaggtg
ctgcatgaatgcaactctccctacatcgtgggcttctatggagccttttacagtgatgga
gagatcagcatctgcatggagcacatggatggtgggtctttggaccaggttctcaaggaa
gccagaagaattcctgaagaaatacttggaaaagttagcatagctgtgttgaggggacta
gcttatctgcgagagaagcaccagatcatgcacagagacgtcaagccctccaacatactg
gtcaactcccgtggggagatcaagctgtgtgactttggcgttagcggccagctcatagat
tccatggccaactcctttgttggaactcgctcctacatgtcgccggagagactgcagggc
acccactactctgttcagtctgacgtgtggagcatgggcctgtccttggtcgagctggcc
atcggccgctatcccatccccccaccagacgccaaagagctggaggccatctttggtcgt
gccattatggacggggcagagggagaggctcacagcaacacacagaggcctagacctcca
ggccggcctgggagtggacatgggatggacagcagacctgccatggccatctttgaactg
ctggactacattgtgaatgagccccctcccaaactgccccacggtgtcttcaccagtgac
ttccaggactttgtgactaaatgcttgattaaaaacccagctgagagagcagatcttaag
atgctcatgagtcacacgttcatcaagcggtcagaggtggaggaggtagactttgcaggc
tggttgtgcaaaaccatgggcctgaaccagcccagtactcccacccgtggcaccgagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (18)   
   KEGG PATHWAY (18)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (9)   
   Pfam (9)   
All databases (47)   

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