KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103727895
Entry
103727895         CDS       T03372                                 
Symbol
Cbl
Name
(RefSeq) Cbl proto-oncogene
  KO
K04707  E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi04012  ErbB signaling pathway
ngi04120  Ubiquitin mediated proteolysis
ngi04144  Endocytosis
ngi04910  Insulin signaling pathway
ngi05100  Bacterial invasion of epithelial cells
ngi05200  Pathways in cancer
ngi05205  Proteoglycans in cancer
ngi05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    103727895 (Cbl)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    103727895 (Cbl)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    103727895 (Cbl)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    103727895 (Cbl)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103727895 (Cbl)
   05205 Proteoglycans in cancer
    103727895 (Cbl)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    103727895 (Cbl)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    103727895 (Cbl)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ngi04131]
    103727895 (Cbl)
   04121 Ubiquitin system [BR:ngi04121]
    103727895 (Cbl)
Enzymes [BR:ngi01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     103727895 (Cbl)
Membrane trafficking [BR:ngi04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    103727895 (Cbl)
Ubiquitin system [BR:ngi04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   CBL proteins
    103727895 (Cbl)
SSDB
Motif
Pfam: Cbl_N Cbl_N3 Cbl_N2 zf-C3HC4 zf-C3HC4_3 Prok-RING_4 zf-RING_2 UBA zf-C3HC4_2 zf-RING_UBOX zf-RING_5 zf-RING_4 zf-rbx1 zf-C3HC4_4
Other DBs
NCBI-GeneID: 103727895
NCBI-ProteinID: XP_008824205
Position
Un
AA seq 915 aa
MAGNVKKSSGAGGGGGSGGSGAGGLIGLMKDAFQPHHHHHHLSPHPPGTVDKKMVEKCWK
LMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTVLSRYEGKMETLGENEYFRVFMEN
LMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFRI
TKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFEF
DIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLG
QWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDHI
KVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCRC
EIKGTEPIVVDPFDPRGSGSLLRQSAEGAPSPNYDDDDDERADDSLFMMKELAGTKVERP
PSPFSMAPQASLPPVPPRLDLLQQRVSVPPTASVLGTASKAASGSLHKDKPLPIPPTLRD
LPPPPPPDRPYCVGAETRSQRRPLPCTPGDCPSREKLPPVPSSRLGDSWLPRPIPKVPVA
TPNASDPWPGRELTNRHSLPFSLPSQMESRIDVPRLGSTFSLDTSMNMNSSPGAGPESEH
PKIKPSSSANAIYSLAARPLPVPKLLPGEQGESEEDTEYMTPSSRPLGVQKPDSKRPLET
SQSSRPCDCDQQIDSYTYEAMYNIQSQATSVTETITFGEGNLVTANTSTGPEESENEDDG
YDVPKPPVPVVLARRTLSDISNASSSFGWLSLDGDPTTNFSEGSQVPERPPKPFPRRINS
ERKASSCQQGGGATAAPTTTAPSPQLSSEIESLMSQGYSYQDIQKALVIAHNNIEMAKNI
LREFVSISSPAHVAT
NT seq 2748 nt   +upstreamnt  +downstreamnt
atggcgggcaacgtgaagaagagctccggcgctgggggtggcggcggctccgggggctcg
ggcgcgggcggcctgatcgggctgatgaaggacgccttccagccgcaccaccaccaccac
cacctcagcccgcacccgccgggcactgtggacaagaagatggtggagaagtgctggaag
ctcatggacaaggtggtacggttgtgtcaaaacccaaagctggctctcaagaatagtcca
ccttatatcttagacctgctacctgatacctaccagcatctccgtactgtcttgtcaaga
tatgaagggaagatggagacacttggagaaaatgaatattttagggtattcatggagaat
ttgatgaagaaaaccaagcagactataagcctcttcaaggagggaaaagaaagaatgtat
gaggagaattctcagcctaggcgaaacctaactaaactgtccctgatcttcagccacatg
ctggcagaactgaaaggcatcttcccaagtggactctttcaaggagatacttttcggatt
actaaagcagatgctgcagaattttggagaaaagcttttggggaaaagacaatagttcct
tggaagagctttagacaggcccttcatgaagtacatcccatcagttctgggctggaggcc
atggctctgaagtccactattgatctgacctgcaatgattatatttcagtttttgaattt
gatatctttacacgactgtttcagccttggtcctctttgcttagaaattggaatagcctt
gctgtcacccaccctggttacatggctttcctgacatatgatgaagtgaaagcgcggctc
cagaaattcattcacaaacctggcagttacatcttccggctgagctgtactcgtctgggt
caatgggctattggatatgttactgctgatgggaacattctgcagacaatccctcacaac
aaacctctcttccaagcactgatcgatggtttcagggaaggcttctatttatttcctgat
ggacgaaatcagaatcctgatctgacaggtttatgtgaaccaacacctcaagatcatatc
aaagtaacccaagaacaatatgaattatactgtgagatgggttccacatttcaactatgt
aaaatatgtgctgaaaacgataaagatgtgaagattgagccctgtggacacctcatgtgc
acatcttgccttacatcctggcaggaatcagaaggtcagggctgtcctttttgtcgatgt
gaaatcaaaggtactgagcccattgtggtagatccatttgatcctagaggcagtggcagc
ctattaagacaaagtgcagaaggagctccttccccaaattacgatgatgatgatgatgaa
cgggctgatgattctctattcatgatgaaggagttggcaggtaccaaggtggaaagacct
ccctctccattctccatggccccacaagcttcccttcctccagtaccaccacgacttgac
cttctacaacagcgagtatctgttcctccaactgcttctgtcctggggactgcttccaag
gctgcttctggttcccttcataaggacaaaccattgccaataccccccacacttcgagat
cttccaccgccacctcctccagaccggccttactgtgttggagcagaaacacgttctcag
agacgccccctgccttgtacaccaggcgattgtccatctagggaaaaactgcctcctgtc
ccctctagccgccttggggactcatggttgcctcgaccaatccctaaggtaccagtagct
acgccaaatgccagtgacccttggcctggaagagagttgaccaaccggcactcacttcca
ttttcattgccctcacaaatggagtccagaatagatgtgcctaggcttggaagtacattt
agtctggatacctccatgaatatgaatagcagcccaggagcaggtccagagagtgagcac
ccgaaaatcaagccttcctcatctgccaatgccatttactccctggctgccaggcctctt
cctgtgccaaaactgctacctggggagcagggtgaaagtgaagaggacacagaatatatg
actccttcctctcggcctcttggggttcaaaagccagactcaaaacggcctttggagaca
tctcagagttcacgaccatgtgattgtgaccaacagattgatagctacacatatgaagca
atgtataatattcagtcccaggcaacatctgtcacagagaccattacctttggagaagga
aatttggttacagctaacaccagcactggtcctgaggaatccgaaaatgaggatgatggc
tatgatgtccctaagcctcctgtgccggttgtgctggctcgccgaactctgtccgacatc
tctaatgccagttcttcctttggctggttgtctctggatggtgaccctaccacaaacttc
agtgagggttctcaagttcctgagcgacctcccaaaccattccctcggagaatcaactct
gaacgaaaagcaagtagctgtcagcaaggtggcggtgccactgctgctcctaccaccact
gctccctcaccacagctctccagtgagattgagagcctcatgagtcagggctactcctac
caggacattcagaaagctttggtcattgcccacaacaacattgaaatggccaaaaacatc
ctccgagaatttgtttctatttcttctcctgcccatgtagccacctag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (8)   
   KEGG PATHWAY (8)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (14)   
   Pfam (14)   
All databases (50)   

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