KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103731682
Entry
103731682         CDS       T03372                                 
Symbol
Mmp2
Name
(RefSeq) matrix metallopeptidase 2
  KO
K01398  matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi01522  Endocrine resistance
ngi04670  Leukocyte transendothelial migration
ngi04912  GnRH signaling pathway
ngi04915  Estrogen signaling pathway
ngi04926  Relaxin signaling pathway
ngi04933  AGE-RAGE signaling pathway in diabetic complications
ngi05200  Pathways in cancer
ngi05205  Proteoglycans in cancer
ngi05219  Bladder cancer
ngi05415  Diabetic cardiomyopathy
ngi05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    103731682 (Mmp2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    103731682 (Mmp2)
   04915 Estrogen signaling pathway
    103731682 (Mmp2)
   04926 Relaxin signaling pathway
    103731682 (Mmp2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103731682 (Mmp2)
   05205 Proteoglycans in cancer
    103731682 (Mmp2)
  09162 Cancer: specific types
   05219 Bladder cancer
    103731682 (Mmp2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    103731682 (Mmp2)
   05415 Diabetic cardiomyopathy
    103731682 (Mmp2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    103731682 (Mmp2)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    103731682 (Mmp2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:ngi01002]
    103731682 (Mmp2)
Enzymes [BR:ngi01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.24  gelatinase A
     103731682 (Mmp2)
Peptidases and inhibitors [BR:ngi01002]
 Metallo peptidases
  Family M10
   103731682 (Mmp2)
SSDB
Motif
Pfam: Peptidase_M10 fn2 Hemopexin PG_binding_1 Reprolysin_5 Reprolysin_3 Peptidase_M66 Reprolysin_4 CBM60
Other DBs
NCBI-GeneID: 103731682
NCBI-ProteinID: XP_008828308
UniProt: A0A8C6RPF3
Position
Un
AA seq 662 aa
MEAQGAWGALASALRAFCVLSCLLGRAIAAPSPIIKFPGDVTPKTDKELAVQYLNTFYGC
PKENCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD
KNQITYRIIGYTPDLDPETVDDAFARALQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD
GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFS
GREYNSCTDTGRSDGFLWCSTTYDFEKDGKYGFCPHEALFTMGGNADGQPCKFPFRFQGT
AYNSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKH
ESCTSAGRSDGKMWCATTTNYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL
MAPIYTYTKNFRLSHDDIKGIQELYGASPDADTDTGTGPTPTLGPVTPEICKQDIVFDGI
AQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGN
EYWVYSASTLERGYPKPLTSLGLPPDVQRIDAAFNWSKNKKTYIFAGDKFWRYNEVKKKM
DPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWL
GC
NT seq 1989 nt   +upstreamnt  +downstreamnt
atggaggcacaaggagcatggggagccctcgccagcgctctgcgggcgttctgcgtcctg
agctgccttctgggtcgcgccatcgccgcaccgtcgcccatcatcaagttccctggcgat
gtcacccccaaaacggacaaagagttggcagtgcaatacctgaacaccttctatggctgc
cccaaggagaactgcaacctgtttgtgcttaaggataccctcaagaagatgcagaagttc
tttgggttgcctcagacaggtgacctcgaccagaacaccatcgagaccatgaggaagcca
cgctgtggcaacccagatgtggccaactataacttctttccccgcaagcccaagtgggac
aagaaccagatcacatacagaatcattggttacactcccgacctggatcctgagacagtg
gatgatgccttcgctcgggccttacaagtgtggagcgatgtgactccactacgcttttct
cgcatccatgatggggaagctgacatcatgatcaactttggccgctgggaacacggagac
ggatacccctttgatggcaaagacgggctcctggcgcatgcctttgccccaggcactggt
gttggaggagactctcactttgatgatgatgagctgtggaccctgggggaagggcaagtg
gtccgggtgaagtacgggaatgccgatggggagtactgcaagttccccttcctgttcagt
ggccgagaatacaacagctgcactgacactggccgcagtgacggcttcctctggtgctcc
accacctatgacttcgagaaggatggcaagtacggcttctgcccccatgaagccctgttc
accatgggtggcaatgctgatggacagccctgcaagttcccgttccgcttccagggcacc
gcctacaacagctgcaccacagagggccgcacggacgggtatcgctggtgtggcaccact
gaggactatgaccgagacaagaagtatgggttctgcccggagaccgccatgtccactgtg
ggtgggaattcggaaggcgccccatgtgtcttccccttcaccttcctgggcaacaagcat
gagagctgcaccagtgctggccggagcgatgggaagatgtggtgcgcaaccaccactaac
tatgatgatgaccggaagtggggtttctgccctgaccaaggatacagcctgttcctcgtg
gcagcccatgagtttggccatgccatggggctggaacactcacaggaccctggggccttg
atggcacccatctatacctacaccaagaacttccgcttgtcccatgatgatatcaaggga
attcaggagctctatggggcctcccctgatgcagacactgacactggcactggccccacc
cctacactgggacctgtcactcctgagatttgcaaacaggacattgtctttgatggcatt
gcccagattcgtggtgagatcttcttcttcaaggaccggtttatttggcggacagtgaca
ccacgtgacaagcccatgggccccttgttggtggcgacattctggcctgagctcccagaa
aagatagatgctgtgtacgaggccccacaggaggagaaggctgtgttctttgcagggaat
gagtactgggtctattctgccagcaccctggagcgagggtaccccaagcccctgaccagc
ctggggttgccccctgatgtccagcgcatagatgcggcctttaactggagcaagaacaag
aagacatacatcttcgctggagacaaattttggagatacaatgaggttaagaagaaaatg
gatcctggcttccccaagctcattgcagatgcctggaatgccatccctgataacctggat
gctgtcgtggacctgcagggcggtggtcacagctacttcttcaaaggtgcttattacctg
aagttggagaaccaaagtctgaagagtgtgaagtttggaagcatcaaatcggactggttg
ggctgttga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (11)   
   KEGG PATHWAY (11)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (35)   
   KEGG ORTHOLOGY (1)   
   RefGene (31)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (9)   
   Pfam (9)   
All databases (65)   

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