KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103743236
Entry
103743236         CDS       T03372                                 
Symbol
Casp1
Name
(RefSeq) caspase 1
  KO
K01370  caspase 1 [EC:3.4.22.36]
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi04148  Efferocytosis
ngi04217  Necroptosis
ngi04613  Neutrophil extracellular trap formation
ngi04621  NOD-like receptor signaling pathway
ngi04623  Cytosolic DNA-sensing pathway
ngi04625  C-type lectin receptor signaling pathway
ngi05014  Amyotrophic lateral sclerosis
ngi05132  Salmonella infection
ngi05133  Pertussis
ngi05134  Legionellosis
ngi05135  Yersinia infection
ngi05164  Influenza A
ngi05171  Coronavirus disease - COVID-19
ngi05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    103743236 (Casp1)
  09143 Cell growth and death
   04217 Necroptosis
    103743236 (Casp1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    103743236 (Casp1)
   04621 NOD-like receptor signaling pathway
    103743236 (Casp1)
   04623 Cytosolic DNA-sensing pathway
    103743236 (Casp1)
   04625 C-type lectin receptor signaling pathway
    103743236 (Casp1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    103743236 (Casp1)
   05164 Influenza A
    103743236 (Casp1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103743236 (Casp1)
   05135 Yersinia infection
    103743236 (Casp1)
   05133 Pertussis
    103743236 (Casp1)
   05134 Legionellosis
    103743236 (Casp1)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    103743236 (Casp1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103743236 (Casp1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:ngi01002]
    103743236 (Casp1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ngi04131]
    103743236 (Casp1)
Enzymes [BR:ngi01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.36  caspase-1
     103743236 (Casp1)
Peptidases and inhibitors [BR:ngi01002]
 Cysteine peptidases
  Family C14: caspase family
   103743236 (Casp1)
Membrane trafficking [BR:ngi04131]
 Autophagy
  Other autophagy associated proteins
   TRIM-directed selective autophagy
    103743236 (Casp1)
SSDB
Motif
Pfam: Peptidase_C14 CARD
Other DBs
NCBI-GeneID: 103743236
NCBI-ProteinID: XP_017656451
Position
Un
AA seq 453 aa
MVGEEAMADNTLREKRKQFVRSVGKGTINGLLDELLQKKVFNQEEMERINCANATVADKA
RDLCDSVIRKGPQACQICIAYICEEDGHLAGTLGLSAAVLTLPLRVLEQDERQRQLPQKK
TGYYSSFYCSEAVIRKGPQACQICIAYICEEDCHLAETLGLSAATKEKQNKEEEVHVGPS
GSLKLCPLERAQSMWKERSSEIYPISDRSTRTRLALIICNIEFEHLSRRAGADVDLRDME
ILLQDLGYTVKVKENLTALEMTTEVMAFADCPEHKTSDSTFLVFMSHGIRDGICGRKYSE
KFADVLQVNTIFQMMNTRNCPSMKDKPKVIIIQACRGGNQGVVWVKDSVEDCVNRELQDP
DFEDDGVQKAHIEKDFIAFCSSTPDNVSWRHPVRGSLFIMNLIKYMKEHAWSCDLEEIFR
KVRFSFEKTECGVQMPTTERVTLTKSFYLFPGL
NT seq 1362 nt   +upstreamnt  +downstreamnt
atggtgggagaggaagccatggctgacaacaccctgagagagaagaggaagcagtttgtc
cgctcagtgggcaaagggacaataaatggcttgctggatgaacttttacagaagaaagtg
ttcaaccaagaagagatggagagaataaattgtgcaaatgccactgttgcagataaggca
cgagatttatgtgactctgtcattcggaaagggccccaggcatgccaaatctgtattgct
tatatttgtgaagaagacggccacctggcaggaactctgggactttctgcagctgtctta
actcttccacttcgtgtcctggaacaggatgaacggcagcggcagctgccacagaagaaa
acgggttactattcttcattttattgctcagaggctgtcattcggaaagggccccaggca
tgccaaatctgtattgcttatatttgtgaagaagactgccacctggcagaaactctggga
ctttctgcagcaactaaggaaaaacaaaacaaagaagaagaggtgcacgtgggaccaagt
gggagcctcaagctttgtcccttagagagagcccaaagcatgtggaaagaaagatcatca
gagatttatccaataagtgatagatccactcgcacacggcttgctctcattatctgcaac
atagagttcgaacatctttccaggagagcaggagctgatgttgacctcagagatatggaa
atattgctacaggatctgggatacacagtgaaagtgaaagaaaatctcactgctctggag
atgactacagaggtgatggcatttgctgactgcccagagcacaagacctctgacagtact
ttcttggtatttatgtctcatggtatccgagatggcatatgtggaaggaaatactctgag
aaattcgcagatgtgttacaagtaaacactatctttcaaatgatgaacactaggaactgc
ccaagtatgaaagacaaacccaaggttatcatcattcaggcctgccgtggagggaaccaa
ggagtggtgtgggtgaaggattctgtagaggactgtgtaaacagagaattacaggatcca
gattttgaagatgatggtgttcagaaagcccatatagaaaaagatttcattgcgttctgc
tcttcgacaccagataacgtgtcttggcggcatcctgtccggggctctcttttcattatg
aacctcatcaaatatatgaaagaacatgcctggtcttgtgacttggaggagattttccga
aaggttcgattttcatttgaaaaaacagaatgtggggtacagatgcccaccactgagagg
gtgactttaacaaaaagtttctacctcttcccaggactttaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (14)   
   KEGG PATHWAY (14)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (30)   

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