KEGG T00565: NIS

Nitratiruptor sp. SB155-2: NIS_0549

Entry

NIS_0549 CDS T00565

Gene name

metH

Definition

5-methyltetrahydrofolate--homocysteine methyltransferase (EC:2.1.1.13)

Orthology

K00548

5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]

Organism

nis Nitratiruptor sp. SB155-2

Pathway

nis00270	Cysteine and methionine metabolism
nis00450	Selenocompound metabolism
nis00670	One carbon pool by folate
nis01100	Metabolic pathways
nis01110	Biosynthesis of secondary metabolites
nis01230	Biosynthesis of amino acids

Class

Metabolism; Amino acid metabolism; Cysteine and methionine metabolism [PATH:nis00270]
Metabolism; Metabolism of other amino acids; Selenocompound metabolism [PATH:nis00450]
Metabolism; Metabolism of cofactors and vitamins; One carbon pool by folate [PATH:nis00670]

SSDB

Motif

Pfam:

S-methyl_trans Pterin_bind B12-binding_2 Met_synt_B12 B12-binding CdhD DeoC TIR-like

Other DBs

NCBI-GI:

152990298

NCBI-GeneID:

5361760

UniProt:

A6Q2F4

Position

545156..548602

AA seq 1148 aa
MIKRLLRERILIIDGAMGTQLQAKANEISADVWEGKEGCNELLNRTAPKVIKSIHEAYAK
VGADIIKTNTFGSMPWVLDEYDLASEAYDLTKRGCELVKEVCETYSTPEKPRFVACSLGP
GTKLPSLGHIDYDAMYVGYSEAARGAKDGGADIFLLETCQDPLQIKAAMHACQDTAPEIP
IMVSVTIEQNGTMLIGTDAATIATILEPFDIISLGFNCGTGPDMVEKHVRVLSEVWDRPI
SVHANAGLPQNRGGYTYYPMGPKEFTELEAKFTSIDGVALLGGCCGTTPQHIKALVDAVE
GKKPLPPKGKQPRSIASLFESRTLMQDPAPFLMGERSNATGSKAFRELLLKSDYEGTLSV
AQQQVRSGAHGIDVSVGFAGRDETKDMHEVIKLYNEKISIPLMPDSTQVPAIEVALKHIG
GRPIINSANLEDGVEKFDKICSLAKRYGAALVLLAIDEEGMAKTKEKKLAVAERMYERAV
NKHGLNPGDLVFDLLTFTVGSGDEEYQTAAIETIEAIRELRRRHPEVGAVLGVSNISFGL
DKHAREYLNSVFLHHCVEAGLTMAIVNVKNLIPYHKISEEDRKVCEDLLFNRRENGDPLF
AFIEHFSKADKKEAASDDELSKLPLEEQIHKLLIDGDKERMMPLLEKAKDEIDPEKIINE
ILIGAMKEVGDLFGSGQMQLPFVLQSAEVMKAAVDYLNQFLPKTDKQSQTTLILGTVKGD
VHDVGKNLVDILLTNNGFKVINLGIKVELEEFIKAYKEHNAQAIGMSGLLVKSTQVMLEN
LKEMKQKGIDAPILLGGAALTKKFVDEFCRPSYDGPIFYCRDAFDGIVAMSRIEEGNFDT
RLGSDSDEEEIVEIKPKEEVKIDPANIILPKPAHVPTPPFWGRKTLEIDPDIAYEWINKR
LLFKQRWGYKSKGLSKEEYQKQLDEKVIPAFNRLRSELGDIFEPTILYGYWPARAVDNEL
YVFGEEFGWQRDEDANREPIENIIGDAIEIFTFPRQSKPPHRCIADYFHDERMDVSAFTC
VSAGNRFSEYEGELFKAGKYHEYHLVHGLSVELAEALAEIAHKQIRIELGILRNEKPDLG
DVKMVGYQGARYSPGYPACPDLELNRHIFNLLQPEEFGITLSETFQIHPEQSTCAIVVHH
PEAKYFNI

NT seq 3447 nt +upstreamnt +downstreamnt
ttgatcaaaagattacttagagaaagaatactgattatagacggtgctatgggcacgcaa
ctccaagcaaaggcaaacgaaatatctgccgatgtctgggaaggcaaagagggatgcaat
gagctattgaatagaaccgcacccaaggttataaaatctatccatgaagcctatgccaaa
gtgggtgccgacatcattaaaacgaacacttttggctcaatgccttgggtacttgatgag
tatgatttggccagtgaagcgtatgatttgacaaagcgagggtgtgagctagtcaaagag
gtttgcgaaacttatagtacacctgaaaaaccgcgtttcgtagcctgctctttggggcct
ggaacgaaactgccgagtcttgggcatatcgattatgatgcaatgtatgtaggatactca
gaagcggcacgaggagccaaagatggaggagctgatatcttcttgcttgaaacctgccag
gatcctttgcagatcaaagctgcaatgcacgcttgccaagatactgctcctgaaattcct
ataatggtaagtgtcaccattgagcaaaacggtacgatgcttatcggtaccgatgctgca
actattgcaaccattttggagccttttgacatcatatccctgggttttaactgtgggact
ggtcccgatatggtggaaaaacatgtaagagtgctgagcgaagtgtgggatcggccaatt
agtgttcatgccaatgcgggattgccgcaaaacagaggaggctatacctactatcctatg
ggaccaaaagagtttacagagcttgaagcaaagtttacttctattgatggtgtggcactg
cttgggggctgttgcggaacgactccacagcatatcaaagctttggtagatgcagttgaa
ggcaaaaagcccctccccccaaaaggcaaacaaccacgctctatcgcaagcctttttgaa
tcgcgtactctcatgcaagatccagcgccattcttgatgggcgagaggagtaatgctact
ggaagtaaagcttttcgtgagctcttactcaaaagcgattatgaagggactttgagtgtc
gctcagcagcaagtcagaagtggagcccacggcattgatgtgagcgttggattcgccggg
cgtgacgagacaaaggatatgcatgaagtcatcaagctctacaatgaaaagatttctatc
cctttgatgccagactccactcaggtacctgctattgaagtagcgctcaagcatattggt
gggcgaccgattatcaactcagccaaccttgaagatggagtagaaaaattcgacaaaatc
tgttccttagccaaacgatatggcgctgcactggtgctgttggcaatcgatgaagagggg
atggcaaaaacaaaggaaaaaaagctcgcagttgccgagcgtatgtatgaaagagctgta
aacaaacatggcctcaatcctggcgatcttgtttttgaccttttgacctttaccgtagga
agtggagatgaggagtatcaaacggcagcgatagagactattgaagccattcgtgaactg
cgaagacgccatccagaggttggagcagttttaggagtttccaatatcagctttggtttg
gacaaacatgcaagggagtaccttaacagtgtctttttgcatcattgtgtcgaagccggt
cttacgatggcgatcgtcaatgtcaaaaatctcattccataccataaaatcagcgaagag
gatcgaaaagtctgtgaagatctgctttttaacagacgagaaaatggcgatccgcttttt
gccttcatcgagcattttagcaaagcggataaaaaagaggctgcaagcgatgatgagttg
agtaaacttccactggaagaacagatccacaagcttctcatcgatggggacaaagagcgg
atgatgccgctgcttgaaaaagcaaaagatgaaattgacccagaaaaaattatcaatgag
atcttgataggtgctatgaaagaggtgggagatctttttggcagcggacagatgcagctg
ccatttgtgctgcaaagtgcagaggtaatgaaagcagcggtggattatcttaatcagttc
ttgccaaaaaccgataagcagtcccaaactactctcattttgggaacagttaaaggggat
gtgcatgatgttggcaaaaacctcgtggatattttgctcacaaacaatggcttcaaagtc
atcaaccttggcatcaaagtagagctcgaagagtttatcaaggcctacaaagaacacaat
gcccaggcgattggaatgagtgggcttctggtcaaatccacccaggtaatgcttgaaaat
ctcaaagagatgaagcaaaaaggtatcgatgctcccatacttttaggcggggctgctttg
acgaaaaagtttgtggatgagttttgccgtccatcgtatgatggaccgattttttattgt
cgcgatgcatttgatggaattgtcgcgatgagcagaatcgaagagggcaatttcgacaca
aggcttggaagtgacagtgatgaggaggagattgtagaaatcaaaccaaaagaggaagta
aaaatcgatccggcaaatataatcttgccaaaaccagcccatgttccaactccaccattt
tggggtagaaaaacgctcgaaattgatccagacatcgcctatgaatggatcaataaaaga
cttctttttaaacagcgttggggttataagtcaaagggtctgagcaaagaggagtatcaa
aagcagctggatgaaaaggtgattccagcttttaacagattaagaagtgagctgggagat
atatttgagccaacaattctctatggctattggcctgcaagagctgtagacaatgagctt
tatgtttttggagaggagtttggctggcaaagagatgaggatgccaatcgtgagccgata
gaaaatattatcggagatgcgatagagatcttcacatttccaagacagtccaagccaccg
catcgatgtattgcagactatttccatgatgaacgaatggatgtgagcgcttttacctgt
gtgagtgcaggaaacagatttagtgaatatgaaggggaactcttcaaagccggaaaatac
catgagtaccatctggtccatggtttaagcgttgaacttgccgaagctttggctgagatt
gcacataagcagatacgcatagagcttgggattttgcgaaatgaaaaaccggatttgggt
gatgtaaagatggtaggttatcaaggagccagatactcaccgggttatccggcttgtccc
gatctggaactcaaccgacacatattcaaccttttgcaacctgaagagtttggcataacc
ttgagtgaaacgtttcagatccatcctgagcagtctacctgtgcgattgtagtacaccat
ccggaagcaaagtatttcaatatatga

All links

Pathway (6)   
   KEGG PATHWAY (6)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
Protein domain (8)   
   Pfam (8)   
All databases (32)   

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