KEGG   Nitratiruptor sp. SB155-2: NIS_0549
Entry
NIS_0549          CDS       T00565                                 
Symbol
metH
Name
(GenBank) 5-methyltetrahydrofolate--homocysteine methyltransferase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
nis  Nitratiruptor sp. SB155-2
Pathway
nis00270  Cysteine and methionine metabolism
nis00450  Selenocompound metabolism
nis00670  One carbon pool by folate
nis01100  Metabolic pathways
nis01110  Biosynthesis of secondary metabolites
nis01230  Biosynthesis of amino acids
Brite
KEGG Orthology (KO) [BR:nis00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    NIS_0549 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    NIS_0549 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    NIS_0549 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04980 Cobalamin transport and metabolism
    NIS_0549 (metH)
Enzymes [BR:nis01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     NIS_0549 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding CdhD DeoC
Other DBs
NCBI-ProteinID: BAF69663
UniProt: A6Q2F4
Position
545156..548602
AA seq 1148 aa
MIKRLLRERILIIDGAMGTQLQAKANEISADVWEGKEGCNELLNRTAPKVIKSIHEAYAK
VGADIIKTNTFGSMPWVLDEYDLASEAYDLTKRGCELVKEVCETYSTPEKPRFVACSLGP
GTKLPSLGHIDYDAMYVGYSEAARGAKDGGADIFLLETCQDPLQIKAAMHACQDTAPEIP
IMVSVTIEQNGTMLIGTDAATIATILEPFDIISLGFNCGTGPDMVEKHVRVLSEVWDRPI
SVHANAGLPQNRGGYTYYPMGPKEFTELEAKFTSIDGVALLGGCCGTTPQHIKALVDAVE
GKKPLPPKGKQPRSIASLFESRTLMQDPAPFLMGERSNATGSKAFRELLLKSDYEGTLSV
AQQQVRSGAHGIDVSVGFAGRDETKDMHEVIKLYNEKISIPLMPDSTQVPAIEVALKHIG
GRPIINSANLEDGVEKFDKICSLAKRYGAALVLLAIDEEGMAKTKEKKLAVAERMYERAV
NKHGLNPGDLVFDLLTFTVGSGDEEYQTAAIETIEAIRELRRRHPEVGAVLGVSNISFGL
DKHAREYLNSVFLHHCVEAGLTMAIVNVKNLIPYHKISEEDRKVCEDLLFNRRENGDPLF
AFIEHFSKADKKEAASDDELSKLPLEEQIHKLLIDGDKERMMPLLEKAKDEIDPEKIINE
ILIGAMKEVGDLFGSGQMQLPFVLQSAEVMKAAVDYLNQFLPKTDKQSQTTLILGTVKGD
VHDVGKNLVDILLTNNGFKVINLGIKVELEEFIKAYKEHNAQAIGMSGLLVKSTQVMLEN
LKEMKQKGIDAPILLGGAALTKKFVDEFCRPSYDGPIFYCRDAFDGIVAMSRIEEGNFDT
RLGSDSDEEEIVEIKPKEEVKIDPANIILPKPAHVPTPPFWGRKTLEIDPDIAYEWINKR
LLFKQRWGYKSKGLSKEEYQKQLDEKVIPAFNRLRSELGDIFEPTILYGYWPARAVDNEL
YVFGEEFGWQRDEDANREPIENIIGDAIEIFTFPRQSKPPHRCIADYFHDERMDVSAFTC
VSAGNRFSEYEGELFKAGKYHEYHLVHGLSVELAEALAEIAHKQIRIELGILRNEKPDLG
DVKMVGYQGARYSPGYPACPDLELNRHIFNLLQPEEFGITLSETFQIHPEQSTCAIVVHH
PEAKYFNI
NT seq 3447 nt   +upstreamnt  +downstreamnt
ttgatcaaaagattacttagagaaagaatactgattatagacggtgctatgggcacgcaa
ctccaagcaaaggcaaacgaaatatctgccgatgtctgggaaggcaaagagggatgcaat
gagctattgaatagaaccgcacccaaggttataaaatctatccatgaagcctatgccaaa
gtgggtgccgacatcattaaaacgaacacttttggctcaatgccttgggtacttgatgag
tatgatttggccagtgaagcgtatgatttgacaaagcgagggtgtgagctagtcaaagag
gtttgcgaaacttatagtacacctgaaaaaccgcgtttcgtagcctgctctttggggcct
ggaacgaaactgccgagtcttgggcatatcgattatgatgcaatgtatgtaggatactca
gaagcggcacgaggagccaaagatggaggagctgatatcttcttgcttgaaacctgccag
gatcctttgcagatcaaagctgcaatgcacgcttgccaagatactgctcctgaaattcct
ataatggtaagtgtcaccattgagcaaaacggtacgatgcttatcggtaccgatgctgca
actattgcaaccattttggagccttttgacatcatatccctgggttttaactgtgggact
ggtcccgatatggtggaaaaacatgtaagagtgctgagcgaagtgtgggatcggccaatt
agtgttcatgccaatgcgggattgccgcaaaacagaggaggctatacctactatcctatg
ggaccaaaagagtttacagagcttgaagcaaagtttacttctattgatggtgtggcactg
cttgggggctgttgcggaacgactccacagcatatcaaagctttggtagatgcagttgaa
ggcaaaaagcccctccccccaaaaggcaaacaaccacgctctatcgcaagcctttttgaa
tcgcgtactctcatgcaagatccagcgccattcttgatgggcgagaggagtaatgctact
ggaagtaaagcttttcgtgagctcttactcaaaagcgattatgaagggactttgagtgtc
gctcagcagcaagtcagaagtggagcccacggcattgatgtgagcgttggattcgccggg
cgtgacgagacaaaggatatgcatgaagtcatcaagctctacaatgaaaagatttctatc
cctttgatgccagactccactcaggtacctgctattgaagtagcgctcaagcatattggt
gggcgaccgattatcaactcagccaaccttgaagatggagtagaaaaattcgacaaaatc
tgttccttagccaaacgatatggcgctgcactggtgctgttggcaatcgatgaagagggg
atggcaaaaacaaaggaaaaaaagctcgcagttgccgagcgtatgtatgaaagagctgta
aacaaacatggcctcaatcctggcgatcttgtttttgaccttttgacctttaccgtagga
agtggagatgaggagtatcaaacggcagcgatagagactattgaagccattcgtgaactg
cgaagacgccatccagaggttggagcagttttaggagtttccaatatcagctttggtttg
gacaaacatgcaagggagtaccttaacagtgtctttttgcatcattgtgtcgaagccggt
cttacgatggcgatcgtcaatgtcaaaaatctcattccataccataaaatcagcgaagag
gatcgaaaagtctgtgaagatctgctttttaacagacgagaaaatggcgatccgcttttt
gccttcatcgagcattttagcaaagcggataaaaaagaggctgcaagcgatgatgagttg
agtaaacttccactggaagaacagatccacaagcttctcatcgatggggacaaagagcgg
atgatgccgctgcttgaaaaagcaaaagatgaaattgacccagaaaaaattatcaatgag
atcttgataggtgctatgaaagaggtgggagatctttttggcagcggacagatgcagctg
ccatttgtgctgcaaagtgcagaggtaatgaaagcagcggtggattatcttaatcagttc
ttgccaaaaaccgataagcagtcccaaactactctcattttgggaacagttaaaggggat
gtgcatgatgttggcaaaaacctcgtggatattttgctcacaaacaatggcttcaaagtc
atcaaccttggcatcaaagtagagctcgaagagtttatcaaggcctacaaagaacacaat
gcccaggcgattggaatgagtgggcttctggtcaaatccacccaggtaatgcttgaaaat
ctcaaagagatgaagcaaaaaggtatcgatgctcccatacttttaggcggggctgctttg
acgaaaaagtttgtggatgagttttgccgtccatcgtatgatggaccgattttttattgt
cgcgatgcatttgatggaattgtcgcgatgagcagaatcgaagagggcaatttcgacaca
aggcttggaagtgacagtgatgaggaggagattgtagaaatcaaaccaaaagaggaagta
aaaatcgatccggcaaatataatcttgccaaaaccagcccatgttccaactccaccattt
tggggtagaaaaacgctcgaaattgatccagacatcgcctatgaatggatcaataaaaga
cttctttttaaacagcgttggggttataagtcaaagggtctgagcaaagaggagtatcaa
aagcagctggatgaaaaggtgattccagcttttaacagattaagaagtgagctgggagat
atatttgagccaacaattctctatggctattggcctgcaagagctgtagacaatgagctt
tatgtttttggagaggagtttggctggcaaagagatgaggatgccaatcgtgagccgata
gaaaatattatcggagatgcgatagagatcttcacatttccaagacagtccaagccaccg
catcgatgtattgcagactatttccatgatgaacgaatggatgtgagcgcttttacctgt
gtgagtgcaggaaacagatttagtgaatatgaaggggaactcttcaaagccggaaaatac
catgagtaccatctggtccatggtttaagcgttgaacttgccgaagctttggctgagatt
gcacataagcagatacgcatagagcttgggattttgcgaaatgaaaaaccggatttgggt
gatgtaaagatggtaggttatcaaggagccagatactcaccgggttatccggcttgtccc
gatctggaactcaaccgacacatattcaaccttttgcaacctgaagagtttggcataacc
ttgagtgaaacgtttcagatccatcctgagcagtctacctgtgcgattgtagtacaccat
ccggaagcaaagtatttcaatatatga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (21)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (7)   
   Pfam (7)   
All databases (53)   

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