KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100587547
Entry
100587547         CDS       T03265                                 
Symbol
PDE2A
Name
(RefSeq) cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X1
  KO
K18283  cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00230  Purine metabolism
nle01100  Metabolic pathways
nle04022  cGMP-PKG signaling pathway
nle04740  Olfactory transduction
nle04925  Aldosterone synthesis and secretion
nle05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:nle00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    100587547 (PDE2A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    100587547 (PDE2A)
 09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    100587547 (PDE2A)
  09157 Sensory system
   04740 Olfactory transduction
    100587547 (PDE2A)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    100587547 (PDE2A)
Enzymes [BR:nle01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     100587547 (PDE2A)
SSDB
Motif
Pfam: PDEase_I GAF GAF_2 GAF_3
Other DBs
NCBI-GeneID: 100587547
NCBI-ProteinID: XP_030684951
Ensembl: ENSNLEG00000017175
Position
15:64064116..64164406
AA seq 942 aa
MGQACGHSILCRSQQYPAARPAEPRGQQVFLKPDEPPPPPPQPCADSLQDALLSLGSVID
ISGLQRAVKEALSAVLPRVETVYTYLLDGESRLVCEDPLHELPQEGKVREAIISRKRLGC
NGLGFSDLPGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQA
VEKHTLVALRRVQALQQRGPREAPRAVQNPPEGAAEDQKGGAAYTDRDRKILQLCGELYD
LDASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQV
VEDKKSIQLKDLTSEDVQQLQSMLGCALQAMLCVPVISRATDQVVALACAFNKLEGDLFT
DQDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIIT
EARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIP
DAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATA
FSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDCN
FASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWM
HAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALY
SSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKD
LQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKA
MGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVS
HKFTIRGLPSNNSLDFLDEEYEVPDLDGTGAPINGCCSLDAE
NT seq 2829 nt   +upstreamnt  +downstreamnt
atggggcaggcatgcggccactccatcctctgcaggagccagcagtacccggcagcgcga
ccggctgagccgcggggccagcaggtcttcctcaagccggacgagccgccgccgccgccg
ccgcagccatgcgccgacagcctgcaggacgctttgctgagtctgggctctgtcatcgac
atttcgggcctgcaacgtgctgtcaaggaggccctgtcagctgtgctcccccgagtggaa
actgtctacacctacctgctggatggggagtcccggctggtgtgtgaggatccgctacat
gagctgccccaggaggggaaagtccgggaggctatcatctcccggaagcggctgggctgc
aatgggctgggcttctcagacctgccagggaagcccttggccaggctggtggctccactg
gctcctgatacccaagtgctggtcatgccgctagcggacaaggaggccggggccgtggca
gctgtcatcttggtgcactgtggccagctgagtgacaatgaggaatggagcctgcaggca
gtggagaagcataccctggtggccctgcggagggtgcaggccctgcagcagcgcgggccc
agggaggctccccgagcggtccagaaccccccggagggggcggcggaagaccagaagggc
ggggcggcgtacaccgaccgcgaccgcaagatcctgcaactgtgcggggaactctacgac
ctggatgcctcttccctgcagctcaaagtgctccaatacctgcagcaggagacccgggca
tcccgctgctgcctcctgctggtgtcggaggacaatctccagctttcttgcaaggtcatc
ggagacaaagtgctcggggaagaggtcagctttcccttgacaggatgcctgggccaggtg
gtggaagacaagaagtccatccagctgaaggacctcacctctgaagatgtgcaacagctg
cagagcatgttgggctgtgcgttgcaggccatgctctgtgtccctgtcatcagccgggcc
actgaccaggtggtggccttggcctgcgccttcaacaagctagaaggagacttgttcacc
gaccaggacgagcatgtgatccagcactgcttccactacaccagcaccgtgctcaccagc
accctggccttccagaaggaacagaaactcaagtgtgagtgccaggctcttctccaagtg
gcaaagaatctcttcacccacctggatgacgtctctgtcctgctccaggagatcatcacg
gaggccagaaacctcagcaacgcagagatctgctctgtgttcctgctggatcagaatgag
ctggtggccaaggtgttcgacgggggcgtggtggatgatgagagctatgagatccgcatc
ccggccgatcagggcatcgcgggacacgtggcgaccacgggccagatcctgaacatccct
gacgcatatgcccatccgcttttctaccgcggcgtggacgacagcaccggcttccgcacg
cgcaacatcctctgcttccccatcaagaacgagaaccaggaggtcatcggtgtggccgag
ctggtgaacaagatcaatgggccgtggttcagcaagttcgacgaggacctggcgacggcc
ttctccatctactgcggcatcagcatcgcccattctctcctatacaaaaaagtgaatgag
gctcagtatcgcagccacctggccaacgagatgatgatgtaccacatgaaggtctctgac
gatgagtataccaaacttctccatgatgggatccagcctgtggctgccattgactgcaat
tttgcaagtttcacctatacccctcgttccctgcctgaggatgacacatccatggccatc
ctgagcatgctgcaggacatgaatttcatcaacaactacaaaattgactgcccgaccctg
gcccggttctgtttgatggtgaagaagggctaccgggatcccccctaccacaactggatg
cacgccttttctgtttcccacttctgctacctgctctacaagaacctggagctcaccaac
tacctcgaggacatcgagatctttgccttgtttatttcctgcatgtgtcatgacctggac
cacagaggcacaaacaactctttccaggtggcctcgaaatctgtgctggctgcactctac
agctctgagggctccgtcatggagaggcaccactttgctcaggccatcgccatcctcaac
acccacggctgcaacatctttgatcatttctcccggaaggactatcagcgcatgctggat
ctgatgcgggacatcatcttggccacagacctggcccaccatctccgcatcttcaaggac
ctccagaagatggctgaggtgggctacgaccgaaacaacaagcagcaccacagactcctc
ctctgcctcctcatgacctcctgtgacctctctgaccagaccaagggctggaagaccacg
agaaagatcgcggagctgatctacaaagaattcttctcccagggagacctggagaaggcc
atgggcaacaggccgatggagatgatggaccgggagaaggcctatatccctgagctgcaa
atcagcttcatggagcacattgcaatgcccatctacaagctgttgcaggacctgttcccc
aaagcagcagagctgtacgagcgcgtggcctccaaccgtgagcactggaccaaggtgtcc
cacaagttcaccatccgcggcctcccaagtaacaactcgctggacttcctggatgaggag
tatgaggtgcctgatctggatggcactggggcccccatcaatggctgctgcagccttgat
gctgagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (4)   
   Pfam (4)   
All databases (49)   

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