KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100588136
Entry
100588136         CDS       T03265                                 
Symbol
IRAK1
Name
(RefSeq) interleukin-1 receptor-associated kinase 1 isoform X1
  KO
K04730  interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04010  MAPK signaling pathway
nle04064  NF-kappa B signaling pathway
nle04620  Toll-like receptor signaling pathway
nle04722  Neurotrophin signaling pathway
nle04936  Alcoholic liver disease
nle05132  Salmonella infection
nle05133  Pertussis
nle05135  Yersinia infection
nle05140  Leishmaniasis
nle05142  Chagas disease
nle05145  Toxoplasmosis
nle05152  Tuberculosis
nle05161  Hepatitis B
nle05162  Measles
nle05168  Herpes simplex virus 1 infection
nle05169  Epstein-Barr virus infection
nle05170  Human immunodeficiency virus 1 infection
nle05171  Coronavirus disease - COVID-19
nle05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:nle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100588136 (IRAK1)
   04064 NF-kappa B signaling pathway
    100588136 (IRAK1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100588136 (IRAK1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100588136 (IRAK1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100588136 (IRAK1)
   05161 Hepatitis B
    100588136 (IRAK1)
   05171 Coronavirus disease - COVID-19
    100588136 (IRAK1)
   05162 Measles
    100588136 (IRAK1)
   05168 Herpes simplex virus 1 infection
    100588136 (IRAK1)
   05169 Epstein-Barr virus infection
    100588136 (IRAK1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100588136 (IRAK1)
   05135 Yersinia infection
    100588136 (IRAK1)
   05133 Pertussis
    100588136 (IRAK1)
   05152 Tuberculosis
    100588136 (IRAK1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100588136 (IRAK1)
   05140 Leishmaniasis
    100588136 (IRAK1)
   05142 Chagas disease
    100588136 (IRAK1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100588136 (IRAK1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100588136 (IRAK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:nle01001]
    100588136 (IRAK1)
Enzymes [BR:nle01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     100588136 (IRAK1)
Protein kinases [BR:nle01001]
 Serine/threonine kinases: TKL group
  IRAK family
   100588136 (IRAK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Death RAMP APH
Other DBs
NCBI-GeneID: 100588136
NCBI-ProteinID: XP_030663418
Position
X:complement(139039524..139049165)
AA seq 714 aa
MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFAALIVRDQTELRLCE
RSGQRTASVLWPWINRNARVADLVHILTHLQLLRARDIITAWHPPAPLPSPSTTAPRPSS
IPAPAEAEAEAWSPRKLPSSAATLLSPAFPGYQTHSGPELGLVPSPASLRPPPPSPAPSS
TKPGPESSVSLLQGAHPSPFCWPLCEISQGTHNFSEELKIGEGGFGCVYRAVMRNTVYAV
KRLKEDADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLED
RLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGD
FGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETL
AGQRAVKTHGARTKYLKDLVEEEAEEAGVAFRSTQSTLQAGLAADAWAAPIAMQIYKKHL
DPRPGPCPPELGLGLGRLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCI
PPSPQENSYVSSTGGAHSGAAPWQPLAVPSGASAQAAEQLQRGPNQPVESDESLGGLSAA
LHSWHLTPSCPLDPGPLREAGCPQGDTAGESSCESGPGFRPTALEGLAPGSSASSSSEPP
QITINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS
NT seq 2145 nt   +upstreamnt  +downstreamnt
atggccggggggccgggcccgggggagcccgcggcccccggcgcccagcacttcttgtac
gaggtgccgccctgggtcatgtgccgcttctacaaagtgatggacgccctggagcccgcc
gactggtgccagttcgccgccctgatcgtgcgcgaccagaccgagctgcggctgtgcgag
cgctccgggcagcgcacggccagcgtcctgtggccctggatcaaccgcaacgcccgtgtg
gccgacctcgtgcacatcctcacgcacctgcagctgctccgtgcgcgggacatcatcaca
gcctggcaccctcccgccccgcttccgtccccaagcaccactgccccgaggcccagcagc
atccctgcacccgccgaggccgaggccgaggcctggagcccccggaagttgccatcctca
gccgccaccctcctctccccagcttttccaggctaccagacccattcagggcctgagctc
ggcctggtcccaagtcctgcttccctgcggcctccaccgccatctccagccccttcctct
accaagccaggcccagagagctcagtgtccctcctgcagggagcccacccctctccattt
tgctggcccctctgtgagatttcccagggcacccacaacttctcagaggagctcaagatc
ggggagggtggctttgggtgcgtgtaccgggcggtgatgaggaacacggtgtatgctgtg
aagaggctgaaggaggacgctgacctggagtggactgcagtgaagcagagcttcctgacc
gaggtggagcagctgtccaggtttcgtcacccaaacattgtggactttgctggctactgc
gctcagaacggcttctactgcctcgtgtacggcttcctgcccaacggctccctggaggac
cgtctccactgccagacccaggcctgcccacctctctcctggcctcagcgactggacatc
cttctgggtacagcccgggcaattcagtttctacatcaggacagccccagcctcatccat
ggagacatcaagagttccaacgtccttctggatgagaggctgacacccaagctgggagac
tttggcctggcccggttcagccgctttgccgggtccagccccagccagagcagcatggtg
gctcggacacagacagtgcggggcaccctggcctacctgcccgaggagtacatcaagacg
ggaaggctggctgtggacacggacaccttcagctttggggtggtagtgctagagacgctg
gctggtcagagggctgtgaagacgcatggtgccaggaccaagtatctgaaagacctggtg
gaagaggaggctgaggaggctggagtggctttcagaagtacccagagcacactgcaagca
ggtctggctgcagatgcctgggctgctcccattgccatgcagatctacaagaagcacctg
gaccccaggcccgggccctgcccacctgagctgggcctgggcctgggccggctggcctgc
tgctgcctgcaccgccgggccaaaaggaggcctcctatgacccaggtgtatgagaggcta
gagaagctgcaagcagtggtggcgggggtgcccgggcattcggaggccgccagctgcatc
cccccttccccgcaggagaactcctacgtgtccagcactggcggtgcccacagtggggct
gccccatggcagcccctggcagtgccatcaggagccagtgcccaggcggcagagcagctc
cagagaggccccaaccagcctgtggagagtgacgagagcctaggtggcctctctgctgcc
ctgcactcctggcacttgactccaagctgccctctggacccaggacccctcagggaggcc
ggctgtcctcagggggacacggcgggagaatcgagctgcgagagtggcccaggattccgg
cccacagccttggaaggactggccccaggcagctctgcctcgtcatcatcagagccaccg
cagattaccatcaaccctgcccgacagaagatggtccagaagctggccctgtacgaggat
ggggccctggacagcctgcagctgctgtcgtccagctccctcccaggcttgggcctggaa
caggacaggcaggggcccgaagaaagtgatgaatttcagagctga

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