KEGG   Neisseria meningitidis FAM18 (serogroup C): NMC0110
Entry
NMC0110           CDS       T00458                                 
Symbol
topA
Name
(GenBank) DNA topoisomerase I
  KO
K03168  DNA topoisomerase I [EC:5.6.2.1]
Organism
nmc  Neisseria meningitidis FAM18 (serogroup C)
Brite
KEGG Orthology (KO) [BR:nmc00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:nmc03032]
    NMC0110 (topA)
   03400 DNA repair and recombination proteins [BR:nmc03400]
    NMC0110 (topA)
Enzymes [BR:nmc01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.1  DNA topoisomerase
     NMC0110 (topA)
DNA replication proteins [BR:nmc03032]
 Prokaryotic type
  DNA Topoisomerases
   NMC0110 (topA)
DNA repair and recombination proteins [BR:nmc03400]
 Prokaryotic type
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHIIR (short-homology-independent illegitimate recombination)
     Facilitator
      NMC0110 (topA)
SSDB
Motif
Pfam: Topoisom_bac zf-C4_Topoisom Toprim Toprim_4 NPL
Other DBs
NCBI-ProteinID: CAM09429
UniProt: A1KRF3
Position
114651..116957
AA seq 768 aa
MAKNLLIVESPSKAKTLKKYLGGDFEILASYGHVRDLVPKSGAVDPDNGFAMKYQLISRN
GKHVDAIVAGAKEAENIYLATDPDREGEAISWHLLEILKSKRGLKNIKPQRVVFHEITKN
AVLDAVAHPREIEMDLVDAQQARRALDYLVGFNLSPLLWKKIRRGLSAGRVQSPALRLIC
ERENEIRAFEAQEYWTVHLDSHKGRSKFTAKLAQYNGAKLEQFDLPNEAAQADVLKELEG
KEAVVTAIEKKKRSRNPAAPFTTSTMQQDAVRKLGFTTDRTMRTAQQLYEGIDVGQGAIG
LITYMRTDSVNLADEALTEIRHYIENKIGKEYLPSAAKQYKTKSKNAQEAHEAIRPTSVY
RTPESVKPFLSADQFKLYQMIWQRTVACQMTPAKFDQTTVDITVGKGVFRVTGQVQTFAG
FLSVYEESSDDEEGEDSKKLPEMSEGDKLPVDKLYGEQHFTTPPPRYNEATLVKALEEYG
IGRPSTYASIISTLKDREYVTLEQKRFMPTDTGDIVNKFLTEHFAQYVDYHFTAKLEDQL
DEIAGGKRQWIPLMDKFWKPFIKQVEEKEGIERAKFTTQELDETCPKCGEHKLQIKFGKM
GRFVACAGYPECSYTRNVNETAEEAAERIAKAEAEQAELDGRECPKCGGRLVYKYSRTGS
KFIGCANYPKCKHVEPLEKPKDTGVQCPQCKKGNLVERKSRYGKLFYSCSTYPDCNYATW
NPPVAESCPKCAWPVLTIKTTKRWGVEKVCPQKECGWKEQIEPPAPKE
NT seq 2307 nt   +upstreamnt  +downstreamnt
atggcgaaaaacctattaatcgtcgaatccccgtccaaagccaaaaccctgaaaaaatat
ttgggcggcgattttgaaatccttgcatcctacggacacgtccgcgacctcgtccccaaa
agcggcgcggtcgatcccgacaacggctttgcgatgaaataccaactcatcagccgcaac
ggcaaacacgtcgatgccatcgtcgccggtgccaaagaagctgaaaacatctacctcgcc
accgacccggatagggaaggcgaagccatttcctggcatcttttggaaatcctcaaatcc
aaacgcggcttgaaaaacatcaagccgcagcgtgtcgtgttccacgaaatcaccaaaaac
gccgtgctcgatgccgttgcccatccgcgcgaaatcgaaatggacttggtcgatgcgcaa
caagcccgccgtgctttggactatttggtcggctttaacctttcgccattgttatggaaa
aaaatccgccgaggtttgagcgcggggcgtgtgcaaagccctgctttgcgcctgatttgt
gagcgcgaaaacgagatccgcgcgtttgaagcgcaggaatattggacggtacatcttgac
agtcacaaaggacgcagcaagttcaccgccaaactcgcccaatacaacggcgcgaaactc
gaacaattcgacctgccgaacgaagccgcgcaagccgacgtgttgaaagaactcgaaggc
aaagaggccgtcgttaccgccattgaaaagaaaaagcgcagccgcaatcctgccgcgccg
ttcaccacttctaccatgcagcaggatgccgtgcgcaaactcggcttcaccaccgaccgc
accatgcgtaccgcccaacagctttatgaaggtatagacgtagggcagggcgcgatcggt
ctgattacctatatgcgtactgacagcgtgaatttggcggatgaagcgttaaccgaaatc
cgccattacatcgaaaacaaaatcggcaaagaatatctgccgagtgccgccaaacaatac
aaaaccaaatccaaaaacgcccaagaagcgcacgaagccatccgtccgacttccgtgtac
cgcacgcccgaaagcgtcaaacccttcctgagcgcagaccagttcaaactctatcaaatg
atttggcagcgtaccgtcgcctgtcagatgacgcctgccaaattcgaccaaaccaccgtc
gatattaccgtcggcaaaggcgtattccgcgtaaccggacaagtgcaaaccttcgcaggc
ttcttgagcgtttatgaagaaagcagcgacgatgaagaaggcgaagacagcaaaaaactg
cccgaaatgagcgaaggcgataaattgcccgtggacaaactctacggcgaacaacacttt
accactccgccgccacgctacaacgaagccacgctggttaaagccctcgaagaatacggc
atcggccgcccctcgacctacgccagcatcatctccacgctcaaagaccgcgaatacgtt
acccttgagcaaaaacgcttcatgcccaccgacacaggcgacatcgtcaacaaattcctg
accgaacacttcgcccaatacgtcgattaccactttaccgccaaactcgaagaccagctt
gacgaaatcgccggcggcaaacgccaatggattcccttgatggacaaattctggaaaccg
ttcatcaaacaagtggaagaaaaagaaggcatcgaacgcgccaaatttaccacgcaggaa
cttgatgaaacctgcccgaaatgcggcgaacacaaactgcaaatcaagttcggcaaaatg
ggccgtttcgttgcgtgtgccggctatcccgagtgcagctacacgcgcaatgtcaatgaa
accgccgaagaagccgcagagcgcatcgccaaagccgaagccgaacaggcagaactcgac
ggacgcgaatgtcctaaatgtggtggacggctggtgtacaaatacagccgtaccggcagt
aaattcatcggttgcgccaactaccccaaatgcaaacacgtcgagccgctggaaaaaccg
aaagataccggcgtccagtgtccgcaatgtaaaaaaggcaacctcgtcgagcgtaaatcc
cgctacggcaaactgttttacagttgcagcacctatcccgactgtaactacgccacatgg
aacccacccgttgcagaaagctgtccaaaatgcgcatggccggttttgaccatcaaaacc
accaaacgctggggtgtagaaaaagtctgcccacaaaaagaatgcggctggaaagaacag
attgaaccgcccgcgccgaaggagtaa

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Ontology (4)   
   KEGG BRITE (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (5)   
   Pfam (5)   
All databases (15)   

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