KEGG   Ornithorhynchus anatinus (platypus): 100075352Help
Entry
100075352         CDS       T01045                                 

Gene name
PRKAA1
Definition
protein kinase, AMP-activated, alpha 1 catalytic subunit
Orthology
K07198  
5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
FoxO signaling pathway
Regulation of autophagy
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Circadian rhythm
Insulin signaling pathway
Adipocytokine signaling pathway
Oxytocin signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Hypertrophic cardiomyopathy (HCM)
Brite
KEGG Orthology (KO) [BR:oaa00001]
 Environmental Information Processing
  Signal transduction
   04068 FoxO signaling pathway
    100075352 (PRKAA1)
   04151 PI3K-Akt signaling pathway
    100075352 (PRKAA1)
   04152 AMPK signaling pathway
    100075352 (PRKAA1)
   04150 mTOR signaling pathway
    100075352 (PRKAA1)
 Cellular Processes
  Transport and catabolism
   04140 Regulation of autophagy
    100075352 (PRKAA1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    100075352 (PRKAA1)
   04920 Adipocytokine signaling pathway
    100075352 (PRKAA1)
   04921 Oxytocin signaling pathway
    100075352 (PRKAA1)
  Environmental adaptation
   04710 Circadian rhythm
    100075352 (PRKAA1)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    100075352 (PRKAA1)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100075352 (PRKAA1)
Enzymes [BR:oaa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     100075352 (PRKAA1)
Protein kinases [BR:oaa01001]
 Serine/threonine protein kinases: CAMK group
  CAMKL family
   100075352 (PRKAA1)
Mitochondrial biogenesis [BR:oaa03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    100075352 (PRKAA1)
  Mitophagy factors
   Other mitophagy factors
    100075352 (PRKAA1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 627 aa AA seqDB search
MSLPRSYPAIKQRALAEPFQAMDFGAENVLSIPYAERENKWLLLSLPPKPLGPEAKTVSE
KNLESDRRLLFEERSRHKKKPSCKSFPFEPELKPESRFDYPEITLGKERCVGKHELTGHK
VAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGEL
FDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLS
NMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPT
LFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIRDIREHEWFKQDLPKYLFPEDP
SYSNTMIDDEALKEVCEKFECTEEEVLSCLYSRNHQDPLAVAYHLIIDNRRIMNEAKDFY
LATSPPDSFLDDHHLSRPHPERVPFLVAETPRSRHTLDELNPQKSKHQGVRRAKWHLGIR
SQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLL
DFRSIDDEIIEAKSGTTTPQRSGSVSNYRSGQKNDSDAEAPGKSSGASLTSSVTSLESPT
ADLTSRPGSHTIEFFEMCANLIKILAQ
NT seq 1884 nt NT seq  +upstreamnt  +downstreamnt
atgtccttaccccgctcttaccctgctattaaacagagagccttggccgaaccttttcaa
gcgatggactttggggcagaaaatgttttatccattccttacgcagagcgagaaaataag
tggctcttgttatcgttacccccgaaaccgctcggacccgaagccaagacagtgtccgag
aaaaatttggagtcggacagacgtctcctttttgaggaacgctcccggcacaagaagaaa
ccctcctgcaaaagttttcctttcgagcctgaactcaaacccgagtcacgattcgactac
cctgaaattactttggggaaggagcgttgcgtcggtaaacatgaactgaccgggcacaaa
gtggccgtgaagatcttgaaccgtcagaagatccggagcctcgatgtagtgggcaagatt
cgccgggagattcagaacctcaagctcttcaggcaccctcatataattaaactgtaccag
gtcatcagcacaccgtctgatattttcatggtgatggagtatgtctcgggaggagagttg
ttcgattacatctgtaaaaatggaaggctggacgagaaggagagtcgccgcctattccag
cagatcctctctggggtggactactgtcacagacatatggtggtccacagagacctgaaa
cctgaaaacgtactgctcgatgctcacatgaatgcaaaaatagccgattttggtctttca
aatatgatgtcagatggagaatttttaagaacaagctgcggctcccccaactatgcagca
ccagaagtaatttcaggaaggttgtatgcgggtccagaagtcgacatatggagcagtgga
gtgattctctatgcgttattgtgtggtacccttccatttgacgacgaccacgtgccaact
ctctttaagaagatatgtgatggcatcttctatactcctcagtacttgaatccttccgtg
ataagccttctgaaacacatgctgcaggtggaccccatgaaaagagccacgatcagagac
atcagggaacacgagtggtttaagcaggacctcccgaagtacctctttcccgaggacccg
tcgtacagtaacaccatgatcgacgacgaagccttgaaagaggtgtgcgagaaattcgag
tgcaccgaggaagaggtgctcagctgcctgtacagcagaaaccaccaggaccctctggcc
gttgcctaccacctcataatcgataaccgaaggataatgaacgaggccaaagacttctat
ctggcgaccagcccgcccgattccttcctggacgatcaccatttgtcccgcccccacccc
gagagagtgccgttcctggtagcggagaccccccggtctcgccacaccctcgacgagctg
aaccctcaaaagtccaagcatcagggggtgcggagggccaagtggcatttgggcatccgg
agtcagagccgacccaacgacatcatggccgaagtttgccgagccatcaagcagctggat
tacgaatggaaggtggtgaacccttattatttacgggtccgacggaagaacccggtgacg
agcacgtactcgaagatgagtctgcagctgtaccaggtggacagcaggacgtacttactg
gatttccgcagcatcgatgatgagatcatcgaagcgaagtccgggacgacaactccgcag
agatcaggttcggtgagcaactatcggtccggccagaagaacgactccgacgcggaagcg
ccgggaaaatcctcgggcgcttccctcacctcatccgtgacctcgctcgaatctcccaca
gccgacttaacctcgcgaccgggaagtcacacgatagagtttttcgagatgtgtgcaaat
ctcattaaaatcctcgcccagtaa

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