KEGG   Ornithorhynchus anatinus (platypus): 100075676
Entry
100075676         CDS       T01045                                 
Symbol
ABL1
Name
(RefSeq) tyrosine-protein kinase ABL1 isoform X1
  KO
K06619  abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
oaa04012  ErbB signaling pathway
oaa04014  Ras signaling pathway
oaa04110  Cell cycle
oaa04360  Axon guidance
oaa04722  Neurotrophin signaling pathway
oaa05200  Pathways in cancer
oaa05206  MicroRNAs in cancer
oaa05208  Chemical carcinogenesis - reactive oxygen species
oaa05220  Chronic myeloid leukemia
oaa05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:oaa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    100075676 (ABL1)
   04014 Ras signaling pathway
    100075676 (ABL1)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    100075676 (ABL1)
 09150 Organismal Systems
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100075676 (ABL1)
  09158 Development and regeneration
   04360 Axon guidance
    100075676 (ABL1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100075676 (ABL1)
   05206 MicroRNAs in cancer
    100075676 (ABL1)
   05208 Chemical carcinogenesis - reactive oxygen species
    100075676 (ABL1)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    100075676 (ABL1)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    100075676 (ABL1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oaa01001]
    100075676 (ABL1)
Enzymes [BR:oaa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     100075676 (ABL1)
Protein kinases [BR:oaa01001]
 Non-receptor tyrosine kinases
  ABL family
   100075676 (ABL1)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase F_actin_bind SH2 SH3_1 SH3_2 SH3_9 Haspin_kinase Kinase-like SH3_6
Other DBs
NCBI-GeneID: 100075676
NCBI-ProteinID: XP_001507150
Ensembl: ENSOANG00000001046
UniProt: A0A6I8PFF6
Position
4:34627621..34767553
AA seq 1149 aa
MGQQPGKVLGDQRRPSLPALHFIKGAGKKEPSRHGGPPCNVFVEHEALQRPVASDFESQG
LSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCE
AQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQR
SISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRN
KPTIYGVSPNYDKWEIERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVE
EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLL
YMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKF
PIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERP
EGCPEKVYELMRACWQWSLSDRPSFAEIHQAFETMFQESSISDEVEKELGKKGVRGVVSN
LLQAPELPTKTRTSRRTAENRDANETPETPNPRGPGECDPLDHEPPVSPLLPRKERTPQD
SGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGPADRKAGGEEETRDL
SNGACTGPPSDAADPNKFQNPSNGAALPNGGVSANSGFRSPHLWKKCSTLTNSRLAANDE
ETNSNSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLSTGRQFDSSTFAGHKSEKPALPR
KRASETKTEVTARGTVTPPPRLLKKNEEAADDVFRDAESSPGSSPPNLTPKLTRRQIAMA
PSSGPTHKDEPGKAPAALGTPGTADLLAPVSKNSSGAFVGNSKASAEESRVRRPKHASES
AGKDKGKLSKLKPAPPPPPPPSSGGKSGKHCHNLSHETAGDPGPGTKSKQPSQPAEPANN
EAAKPNQVGEGAKKPVLPSAPKLQSSAKLLLSSSTTPAPSPSTVPSASSTLGGDQQSSTA
FIPLISTRVSLRKTRQPPERIASGTITKGVVLESTDALCLAISRNSEQMASHSAVLEAGK
NLYTFCVNYVDSIQQMRNKFAFREAINKLENNLRELQICPATAGGGPAATQDFSKLLSSV
KEISDIVQR
NT seq 3450 nt   +upstreamnt  +downstreamnt
atggggcaacagcctggaaaagttcttggggaccagaggcgaccaagtttgcctgccctg
cactttatcaaaggagcagggaagaaggaaccatccaggcacggaggtccaccttgcaat
gtttttgtggaacatgaagcccttcagagaccagtagcatctgattttgaatcccaaggc
ctgagtgaagcagctcgttggaactctaaggaaaatcttcttgctggtcccagtgaaaat
gaccctaacctttttgttgcactctatgattttgtggccagtggagacaacactctaagc
atcactaaaggtgaaaagctccgcgtcttgggctacaatcacaacggggaatggtgcgaa
gcccagaccaagaatgggcaagggtgggtccccagcaactacatcactccagtaaatagt
ttggagaaacattcttggtaccacggaccggtctcccgcaacgcggccgagtacctgctg
agcagcggaatcaatgggagttttctggtgcgggagagcgagagcagtccagggcagagg
tccatatcattgagatacgagggaagggtttaccactacaggatcaacactgcatccgac
ggaaagctgtacgtctcctcggagagtcgctttaacactctggcggagttggtccaccac
cactcaacggtagcagatggattgattaccactttacattacccggctcccaagaggaac
aagcccaccatctacggagtgtctcccaactacgataagtgggaaattgagcggacagat
atcaccatgaagcacaagttaggaggcgggcagtatggtgaagtgtacgaaggcgtatgg
aagaaatatagcctgacggtggctgtaaaaaccttaaaggaggacactatggaggtggaa
gagttcctgaaagaagctgcagtaatgaaagagatcaaacatcctaacttggtacaatta
ctaggggtctgtacccgggagcccccgttctatataatcaccgagttcatgacctatggg
aacctgttggattacctgcgagagtgtaaccggcaggaggtgaacgctgtggtgctactg
tacatggccactcagatctcatcagctatggagtatctggagaagaaaaacttcatccac
agggatctggctgcccgaaactgccttgtaggggaaaaccacttggtgaaggtagcggat
tttggtttgagcagattaatgacgggggacacctacaccgcccacgctggggccaagttc
ccgatcaaatggacggcaccggaaagcctggcctataataaattttccattaagtcggat
gtgtgggcatttggtgttttgctgtgggaaatcgccacttatggcatgtccccttatcct
gggattgatctgtcacaagtgtacgagctgttggaaaaagactatcggatggagcgtcct
gaaggctgcccggaaaaggtctatgaactcatgagagcatgctggcagtggagtctttcc
gaccgaccctcctttgctgaaatccaccaggcttttgaaacgatgttccaggagtccagt
atatcagatgaggtggagaaggagctgggaaagaaaggagtacgaggtgtggttagtaac
ttgctgcaggctccggaactgccaaccaaaaccaggacgtccaggagaacagctgaaaac
cgagatgcgaacgaaacacctgaaactcctaatcccagaggcccaggagaatgtgatccg
ttggaccacgaacctcccgtgtctccgctgctcccccggaaagaaagaacaccccaagac
agtgggttgaatgaagacgagcgcctccttccgaaagataagaagaccaacctgttcagc
gccctaatcaagaagaagaagaaaacggcccccacgccgccgaaacgcagcagttccttc
cgggagatggacggccccgcagaccgcaaggccggaggggaggaagagacccgagacctc
agcaacggggcctgcaccggccctccctcggatgcggccgacccgaataagttccagaac
ccgagcaacggggcggccctccccaacgggggcgtgtcggctaattcgggcttccgatct
cctcacttgtggaagaagtgcagcacgctcaccaacagccggttggcggccaacgacgaa
gagactaactccaactcgagcaaacgcttcttgagatcctgttcagcgtcctgcgtgccc
cacggggccaaggacaccgagtggcggtccgtcaccctgccccgggatctgtccaccggg
cgacagttcgactcctccacgttcgcgggccacaaaagcgaaaagccggccttgcctcgg
aagcgggcgagcgagaccaagaccgaagtaaccgcccggggcacggtgacccccccgccc
cggctgctgaagaagaacgaagaagcggccgacgacgtcttcagggacgccgagtccagc
cccggctccagtcctcccaacctgacgcccaagctcacccgtaggcagatcgcgatggcg
ccttcctccggcccgacccacaaggatgagcctggaaaggcccctgcggccttggggacc
cccgggaccgctgacctcctggcgccggtcagcaagaactcgtccggcgccttcgtgggg
aacagcaaggcctccgccgaggagtccagagtgaggaggcccaagcacgcttcggagtcg
gcgggaaaggacaagggaaaattatcgaagctcaagcccgccccgcccccgccaccgcca
ccatcctctgggggcaagtccgggaagcactgccataacctcagccacgaaacggcaggg
gacccggggcccgggaccaaatccaaacagccgtctcagccggccgagccggcgaacaac
gaagccgccaagccaaaccaggtaggggagggggccaaaaagcccgtcctcccatcggcc
cccaagctgcagtcgtcggctaagctgttgctctcttcctcgacgactccggccccctcg
ccctccaccgtgccatctgcttcctccactctaggaggggaccagcagtcttccaccgcc
ttcatacctctcatatccacccgcgtgtctctgcggaaaacccgccagccgccagagagg
attgccagcggcaccatcaccaagggggtggttttggaaagcaccgacgccctgtgcctg
gccatctccagaaactccgagcaaatggccagccacagcgcggtgttggaagcgggcaag
aacctctatacgttctgcgtgaactacgtggactccatccagcagatgagaaacaaattc
gccttccgagaggccatcaacaaattggaaaataacctccgggagctgcagatctgcccc
gccaccgctggcggcggccccgcggccacccaagactttagcaaactcctcagctcggtc
aaagaaatcagtgacattgttcagaggtag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (31)   
   KEGG ORTHOLOGY (1)   
   RefGene (26)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (10)   
   Pfam (10)   
All databases (63)   

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