KEGG   Ornithorhynchus anatinus (platypus): 100076965Help
Entry
100076965         CDS       T01045                                 

Gene name
TGFBR2
Definition
transforming growth factor, beta receptor II (70/80kDa)
Orthology
K04388  
TGF-beta receptor type-2 [EC:2.7.11.30]
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
MAPK signaling pathway
Cytokine-cytokine receptor interaction
FoxO signaling pathway
Endocytosis
TGF-beta signaling pathway
Osteoclast differentiation
Hippo signaling pathway
Adherens junction
Chagas disease (American trypanosomiasis)
HTLV-I infection
Pathways in cancer
Transcriptional misregulation in cancer
Colorectal cancer
Pancreatic cancer
Chronic myeloid leukemia
Module
TGF-beta signaling
Brite
KEGG Orthology (KO) [BR:oaa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    100076965 (TGFBR2)
   04350 TGF-beta signaling pathway
    100076965 (TGFBR2)
   04390 Hippo signaling pathway
    100076965 (TGFBR2)
   04068 FoxO signaling pathway
    100076965 (TGFBR2)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100076965 (TGFBR2)
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    100076965 (TGFBR2)
  Cellular commiunity
   04520 Adherens junction
    100076965 (TGFBR2)
 Organismal Systems
  Development
   04380 Osteoclast differentiation
    100076965 (TGFBR2)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100076965 (TGFBR2)
   05202 Transcriptional misregulation in cancers
    100076965 (TGFBR2)
   05210 Colorectal cancer
    100076965 (TGFBR2)
   05212 Pancreatic cancer
    100076965 (TGFBR2)
   05220 Chronic myeloid leukemia
    100076965 (TGFBR2)
  Infectious diseases
   05166 HTLV-I infection
    100076965 (TGFBR2)
   05142 Chagas disease (American trypanosomiasis)
    100076965 (TGFBR2)
Enzymes [BR:oaa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     100076965 (TGFBR2)
Protein kinases [BR:oaa01001]
 Serine/threonine protein kinases: TKL group
  TGFBR2 family [OT]
   100076965 (TGFBR2)
Enzyme-linked receptors [BR:oaa01020]
 Receptor serine/threonine kinases
  Type II TGF-beta receptor
   100076965 (TGFBR2)
Cytokine receptors [BR:oaa04050]
 TGF-beta receptors
  Type II TGF-beta receptor
   100076965 (TGFBR2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 559 aa AA seqDB search
MGRPVLGLLTGLLGTCLAATVPPPGRTSDNLFPNHVAESAMKFPGLCKFCDVESTICTNQ
GVCKSNCSITSICENTFDICAAVWRKNDENITLETICHDQRLPLHGFDLDDIGSSKCMMK
EKKMLGETMFMCSCSSEECNDLLYFSEEVAANPELMAVTVISLLPPLGIAVAVIVTFYCY
RVQRRRKLNTAWEKSSKGRKHMECSDRCAMMIDDDRSDISSTCANNLNHNTELLPIELDT
LVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLKHENVLQFL
TAEERKTELGKQYWLITAFHSRGNLQEYLTRHVISWEDLWKLGSSLSRGIAHLHSDHTPC
GRPKTPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPE
VLESRMNLENVESFKQTDVYSMALVLWEMTSRCNGIGEVKDYEPPFGSKVREHPCVESMK
DNVLRDRGRPEIPNTWLSHQGIQTVCETLTECWDHDPEARLTAQCVAERFGELEHLDRLS
GRSCSEEKIPEDCSVNATK
NT seq 1680 nt NT seq  +upstreamnt  +downstreamnt
atgggccggcccgtcctggggctgctgaccggcctcctggggacctgcctggccgccacc
gtcccccctccgggccggacttcggataatttatttcctaatcatgtggccgagagtgcc
atgaaattccccggattgtgcaagttttgtgatgtggaatcaactatctgcaccaaccag
ggggtctgcaagagcaactgcagcatcacttctatctgtgagaatacctttgacatctgt
gcagctgtttggagaaagaatgacgaaaatataaccttggagaccatctgccatgatcag
aggctcccactccatggctttgacctagatgacattggatcttcaaaatgtatgatgaag
gaaaaaaaaatgcttggagaaacaatgttcatgtgttcctgcagctctgaggaatgcaat
gatttgctttacttctcagaagaagtcgccgccaacccagagctgatggcggtgacggtg
atcagcctcctccccccgctggggatcgccgtcgctgtgatcgtcaccttctactgctac
cgggtgcagcgcaggcggaagctgaacacggcctgggagaagagctcgaagggccggaag
cacatggagtgcagcgaccgctgcgccatgatgatcgacgacgaccgctccgacatcagc
tccacctgcgccaacaacctcaaccacaacaccgagctgctgcccatcgagctggacacc
ctggtggggaagggaaggttcgccgaggtctacaaggccaagctgaagcagaacacgtcc
gagcagttcgagacggtggcggtgaagatcttcccctacgaggagtacgcctcctggaag
acggagaaggacatcttctccgacatcaacctgaagcacgagaacgtcctccagttcctc
acggccgaggagcggaagacggagctgggcaagcagtattggctgatcaccgccttccac
tcgcgggggaacctgcaggagtacctgacccggcacgtcatcagctgggaggacctgtgg
aagctgggcagctccctgtcgcggggcatcgcccacctgcacagcgaccacaccccttgc
gggcggcccaagacccccatcgtgcacagagacctgaagagttccaacatcctcgtcaag
aacgacctgacctgctgcctctgtgacttcgggctgtccctgaggctggatcccacgctc
tccgtggacgacctggccaacagcgggcaggtcggcacagcgagatacatggctcctgaa
gtcttggagtcccgaatgaacttagagaacgttgagtctttcaagcaaactgatgtgtac
tccatggctctggtcctctgggagatgacctctcgctgcaacggaataggagaagttaaa
gactacgaacctcccttcggttccaaggtgagagagcatccctgcgtagaaagcatgaag
gacaacgtgttgagagatcgaggacggcccgagatacccaacacgtggctcagtcaccag
gggatccagacggtgtgcgagacgctgacagagtgctgggatcacgaccccgaagctcgg
ctcacggctcagtgcgtggcggagcggttcggcgaactggagcacctggacaggctgtcg
gggagaagttgttcggaggagaagatccccgaggactgctccgtgaacgctaccaaatag

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