KEGG   Ornithorhynchus anatinus (platypus): 100077524Help
Entry
100077524         CDS       T01045                                 

Gene name
HADHA
Definition
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
Orthology
K07515  
enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
Fatty acid elongation
Fatty acid degradation
Valine, leucine and isoleucine degradation
Lysine degradation
Tryptophan metabolism
beta-Alanine metabolism
Propanoate metabolism
Butanoate metabolism
Biosynthesis of unsaturated fatty acids
Metabolic pathways
Carbon metabolism
Fatty acid metabolism
Module
Malonate semialdehyde pathway, propanoyl-CoA => Acetyl-CoA
Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
Fatty acid biosynthesis, elongation, mitochondria
beta-Oxidation
Brite
KEGG Orthology (KO) [BR:oaa00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    100077524 (HADHA)
   01212 Fatty acid metabolism
    100077524 (HADHA)
  Carbohydrate metabolism
   00640 Propanoate metabolism
    100077524 (HADHA)
   00650 Butanoate metabolism
    100077524 (HADHA)
  Lipid metabolism
   00062 Fatty acid elongation
    100077524 (HADHA)
   00071 Fatty acid degradation
    100077524 (HADHA)
   01040 Biosynthesis of unsaturated fatty acids
    100077524 (HADHA)
  Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    100077524 (HADHA)
   00310 Lysine degradation
    100077524 (HADHA)
   00380 Tryptophan metabolism
    100077524 (HADHA)
  Metabolism of other amino acids
   00410 beta-Alanine metabolism
    100077524 (HADHA)
Enzymes [BR:oaa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.211  long-chain-3-hydroxyacyl-CoA dehydrogenase
     100077524 (HADHA)
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.17  enoyl-CoA hydratase
     100077524 (HADHA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
Un
AA seq 763 aa AA seqDB search
MVAARAIGSLSRLTVNGRSRFPGYVSRNFTQSSTLLSRTHINYAVKGDVAVVRINSPNSK
VNTLNKELKLEFMQVMNEIWASEAIRSAVLISAKPGCFIAGADLNMLADCKSPQEVTQLS
QEGQQMLEKLEKSPKPIVAAISGSCLGGGLELAIACQYRIATKDKKTVLGVPEVLLGILP
GAGGTQRLPKMVGVPAAFDMMLTGRNIRADRAKKMGLVDQLVEPLGPGLKAPEERTIEYL
EEVAVTFAKDLADKKVSAKKNKSLVEKVTSYAMTIPFVRQQIYKTVEEKVRKQTKGLYPA
PLKIIDVVKTGLEEGNDAGYLSESQKFGELIMTNESKALVGLYHGQVLCKKNKFGAPQKD
VKHLAILGAGLMGAGIAQVSVDKGLKTILKDTTLTGLGRGQQQVFKGLNDKVKKKNLTSF
ERDSIFSTLTGQLDYQGFEKADMVIEAVFEDLNIKHKVLKEVEAVIPAHCVFASNTSALP
INEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTTASAVAVGLKQGKVIIVVK
DGPGFYTTRCLAPMMSEVVRALQEGVEPKKLDSLTTSFGFPVGAATLVDEVGVDVAGHVS
EELGKAFGERLGGGSPELLKLMVNKGFLGRKAGKGFYIYQEGVKNRSLNSGMDEILTQLR
VSARPEVSTDEDIQYRLVTRFVNEAAMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRF
TDLYGARKLVDRLKKYEDVYGKQFTPCQLLVDHANNPDKKFYQ
NT seq 2292 nt NT seq  +upstreamnt  +downstreamnt
atggtggccgcgcgggccatcggcagcctcagccgcctcaccgtcaacggccggagccgc
ttcccaggttatgtctcccgaaactttactcagtcttccactttactatccagaacccat
attaactatgccgtcaaaggggatgtggccgtggtccgaatcaactccccaaattcaaag
gtaaacactctgaacaaagagttgaagttggagttcatgcaagtaatgaatgagatttgg
gccagtgaagccatcagaagtgcagtcctcatttcagcaaagccaggctgctttattgct
ggtgctgatctcaacatgctagcagattgtaagagtcctcaggaagtgacacaactatct
caagaaggacagcaaatgctggagaagcttgaaaagtccccgaagcctattgtagctgcc
atcagtggatcctgcttgggaggaggactggagcttgccatcgcctgccagtacagaata
gcaacaaaagacaaaaagactgtattgggtgttcctgaagtgctactggggatattgcca
ggggcgggaggcacacagaggctcccaaagatggtgggtgtccccgctgcctttgacatg
atgcttactggtagaaacattcgtgctgacagagcaaagaagatgggacttgttgaccaa
ttggtggagcctctgggaccaggtttgaaagctccagaagaaaggacaattgaatacctt
gaagaagtagccgttacttttgctaaagacctagctgataaaaaggtttctgccaagaag
aacaagagtctggtggagaaggtgacatcctacgccatgacaattccatttgtcaggcaa
cagatctacaaaacagtggaagaaaaagttagaaagcagaccaaagggctgtatcctgct
cccctgaagatcattgatgttgttaagactggacttgaagaggggaatgatgctgggtat
ctgtcggaatcccagaaatttggtgaacttataatgaccaatgaatccaaggctttggtt
ggactctaccatggtcaagttctgtgcaagaaaaataagtttggggcccctcagaaggat
gtcaagcatctggctattcttggagcagggctcatgggagctggcattgctcaagtctca
gtggataaggggttgaagaccattctcaaagacaccacattaacaggcttgggcagagga
cagcagcaagtcttcaaagggttaaatgacaaagtgaagaagaagaatctgacgtcattt
gaaagggactccatcttcagcaccctaacggggcagctcgattaccagggatttgagaag
gcagacatggtgattgaagctgtctttgaggacctcaacattaagcacaaagtgctgaag
gaggtggaagctgtaattcctgctcactgtgtctttgccagtaacacatctgctctccca
atcaatgaaattgctgccgtcagcaaaaggcctgaaaaggttattggcatgcactacttc
tctccagtggacaagatgcagttactagagatcatcacgacagaaaaaacctccaaagac
acaactgcctctgctgtagcagttggcctcaaacagggcaaagtcatcattgtggtcaag
gatgggccgggcttttacaccaccaggtgcctcgcccccatgatgtctgaagttgtccgg
gctctgcaggaaggcgttgagcctaagaaattggattccttgaccaccagctttggcttt
cctgtgggtgctgccaccctggtggatgaagttggtgtggatgtggccggacacgtctca
gaggagctgggcaaagcctttggggagcggttaggcggtggaagcccagaactgctgaag
ctcatggtgaataaaggcttcctgggtcgcaaagctgggaaaggtttttatatctaccag
gagggcgtcaagaaccgaagtttgaattctggcatggatgagattctgacccagttgagg
gtctcggcccgacctgaggtctccactgatgaagacattcaatatcgactggtgacgcgg
ttcgtcaatgaggcagccatgtgcctacaggaggggatcctggccacgcccgcggaggga
gacatcggggcagtgttcgggctcggcttcccgccttgtctcggaggtcccttccgtttc
acagacctgtacggtgcccggaagcttgtggatcgactcaagaagtatgaggatgtgtat
gggaaacagttcaccccatgtcagctgctggtagaccacgctaacaacccagacaagaag
ttttatcagtga

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