KEGG   Ornithorhynchus anatinus (platypus): 100078046Help
Entry
100078046         CDS       T01045                                 

Gene name
PIK3CG
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Signaling pathways regulating pluripotency of stem cells
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:oaa00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100078046 (PIK3CG)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100078046 (PIK3CG)
   04015 Rap1 signaling pathway
    100078046 (PIK3CG)
   04012 ErbB signaling pathway
    100078046 (PIK3CG)
   04370 VEGF signaling pathway
    100078046 (PIK3CG)
   04630 Jak-STAT signaling pathway
    100078046 (PIK3CG)
   04668 TNF signaling pathway
    100078046 (PIK3CG)
   04066 HIF-1 signaling pathway
    100078046 (PIK3CG)
   04068 FoxO signaling pathway
    100078046 (PIK3CG)
   04070 Phosphatidylinositol signaling system
    100078046 (PIK3CG)
   04024 cAMP signaling pathway
    100078046 (PIK3CG)
   04022 cGMP - PKG signaling pathway
    100078046 (PIK3CG)
   04151 PI3K-Akt signaling pathway
    100078046 (PIK3CG)
   04152 AMPK signaling pathway
    100078046 (PIK3CG)
   04150 mTOR signaling pathway
    100078046 (PIK3CG)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100078046 (PIK3CG)
  Cell growth and death
   04210 Apoptosis
    100078046 (PIK3CG)
  Cellular commiunity
   04510 Focal adhesion
    100078046 (PIK3CG)
   04550 Signaling pathways regulating pluripotency of stem cells
    100078046 (PIK3CG)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100078046 (PIK3CG)
   04620 Toll-like receptor signaling pathway
    100078046 (PIK3CG)
   04650 Natural killer cell mediated cytotoxicity
    100078046 (PIK3CG)
   04660 T cell receptor signaling pathway
    100078046 (PIK3CG)
   04662 B cell receptor signaling pathway
    100078046 (PIK3CG)
   04664 Fc epsilon RI signaling pathway
    100078046 (PIK3CG)
   04666 Fc gamma R-mediated phagocytosis
    100078046 (PIK3CG)
   04670 Leukocyte transendothelial migration
    100078046 (PIK3CG)
   04062 Chemokine signaling pathway
    100078046 (PIK3CG)
  Endocrine system
   04910 Insulin signaling pathway
    100078046 (PIK3CG)
   04915 Estrogen signaling pathway
    100078046 (PIK3CG)
   04914 Progesterone-mediated oocyte maturation
    100078046 (PIK3CG)
   04917 Prolactin signaling pathway
    100078046 (PIK3CG)
   04921 Oxytocin signaling pathway
    100078046 (PIK3CG)
   04919 Thyroid hormone signaling pathway
    100078046 (PIK3CG)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100078046 (PIK3CG)
  Digestive system
   04973 Carbohydrate digestion and absorption
    100078046 (PIK3CG)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100078046 (PIK3CG)
  Nervous system
   04725 Cholinergic synapse
    100078046 (PIK3CG)
   04722 Neurotrophin signaling pathway
    100078046 (PIK3CG)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100078046 (PIK3CG)
  Development
   04380 Osteoclast differentiation
    100078046 (PIK3CG)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100078046 (PIK3CG)
   05230 Central carbon metabolism in cancer
    100078046 (PIK3CG)
   05205 Proteoglycans in cancer
    100078046 (PIK3CG)
   05203 Viral carcinogenesis
    100078046 (PIK3CG)
   05210 Colorectal cancer
    100078046 (PIK3CG)
   05212 Pancreatic cancer
    100078046 (PIK3CG)
   05214 Glioma
    100078046 (PIK3CG)
   05221 Acute myeloid leukemia
    100078046 (PIK3CG)
   05220 Chronic myeloid leukemia
    100078046 (PIK3CG)
   05218 Melanoma
    100078046 (PIK3CG)
   05211 Renal cell carcinoma
    100078046 (PIK3CG)
   05215 Prostate cancer
    100078046 (PIK3CG)
   05213 Endometrial cancer
    100078046 (PIK3CG)
   05222 Small cell lung cancer
    100078046 (PIK3CG)
   05223 Non-small cell lung cancer
    100078046 (PIK3CG)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100078046 (PIK3CG)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100078046 (PIK3CG)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    100078046 (PIK3CG)
   05166 HTLV-I infection
    100078046 (PIK3CG)
   05162 Measles
    100078046 (PIK3CG)
   05164 Influenza A
    100078046 (PIK3CG)
   05161 Hepatitis B
    100078046 (PIK3CG)
   05160 Hepatitis C
    100078046 (PIK3CG)
   05169 Epstein-Barr virus infection
    100078046 (PIK3CG)
   05146 Amoebiasis
    100078046 (PIK3CG)
   05145 Toxoplasmosis
    100078046 (PIK3CG)
   05142 Chagas disease (American trypanosomiasis)
    100078046 (PIK3CG)
Enzymes [BR:oaa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     100078046 (PIK3CG)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 1109 aa AA seqDB search
MDPEAPEPPVLLREAAKRRRRRMKAYGTPGPPVPPAPSELIPIEFTLPARRRDSPETPET
VTLDVPGNGSVEQMKAQLWAHAAELGPVGAFFQRSCPDQFLLLYQKRGQWYEVYDRHQAV
QTLDCVLHWKVTRLPVGHIRVAPRPQPTPEVLDFQRRLTELIGYDVTDVSNVHDDELEST
RRRLLAPRAAEVAGRDPGLYAMHPWVTSKPLPAYLQGKVANGHVLLVIHRGTTSQTVKVS
VDETPGAILRGFFTRMAKKKSLMGIPEGLGERDFVLRVCGRDEYLVGETPVKNFQWVRQC
LKNGEDIHLVLDAPPDPALDRVREEEWPLVDDGPGATGYHDQLTVAGKSHERVLTVSLWD
CDRRFRVKIRGFDGPAAPPRGPEPTVFVEAKVQHGQQLLSQSRTTSKPWAEEVLWNQWLE
FGIRIKDLPRGALLNLQIYCGRAQGGPPPAPGSPGPGSDPRARHQLLYYVNLLLVDHRSL
LRRGGYVLHMWKTSGKEDGRGSLNADKLTSATNPDKENSVAISVLLDDYCHPVALPKHRP
ASGPDGAGAGAGGRAEMPNQLRKQLEEIVATDPLHPLSAEDKELLWHFRHESLKHPEAYP
KLFSAVDWGRQETVAVAYRLLARREVWDRSALDVGLTLQLLDCNFSDENVRAMAVQKLES
LEDDDVLHFLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSPHYQ
QRFAVLLEAYLRGCGQAMLQDFTRQVQVTRLLHKLTLEIKSLSADKYDVTPQVVAQLKEK
LENLQNSHLPDSFRVPYDPGLKAGKLVIEKCKVMASKKKPLWLEFQCADPTALSSETIGV
IFKHGDDLRQDMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGKPPLGASENSLSX
AISQKDLGSDPGSANCLLCDLGRVTSLLCASVSSAVQRVFNTCSLKLTSTLYTGAXNPDS
SLLLGNLFHIDFGHILGNYKSFLGISKERVPFVLTPDFLFVMGTAGKKTSKHFQKFQEVC
VRAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIAYIRDALTVGKSEEEAEKYFLDQIE
VCRDKGWTVQCNWFLHLVLGIKQGEKHST
NT seq 3330 nt NT seq  +upstreamnt  +downstreamnt
atggatcccgaggccccggagccgcccgtccttctgagagaggcggccaagaggaggcgg
cggaggatgaaggcctacggcaccccgggcccgccggtccccccggctccctcggagctg
atccccatcgagttcaccctgcccgcccggcggcgggactccccggagacccccgagacg
gtgaccctggacgtgccggggaacggcagcgtggagcagatgaaggcccagctgtgggcc
cacgcggccgagctgggcccggtcggggccttcttccagcgcagctgccctgaccagttc
ctgctgctctaccagaagaggggccagtggtacgaggtgtatgaccggcaccaggccgtg
cagaccctggactgcgtgctccactggaaggtcacgcgtctgcccgtgggccacatccgg
gtggcgcccaggccgcagcccaccccggaggtgctggacttccagcgccgtctgaccgag
ctgatcggctacgacgtgacggacgtgagcaacgtgcacgacgacgagctggagtccacc
cgccgccggctgctggccccgcgggcggccgaagtggccggccgggaccccgggctctac
gccatgcacccctgggtcacgtccaagccgctgcccgcctacctgcagggcaaggtggcc
aacggccacgtcctgctggtcatccaccggggcaccaccagccagacggtgaaggtatcc
gtggacgagacccccggggccatcctgcggggcttcttcacccggatggccaagaagaag
tcgctgatgggcatccccgagggcctgggcgagcgggacttcgtgctgcgggtctgcggg
cgggacgagtacctggtgggcgagacacccgtcaagaacttccagtgggtccggcagtgc
ctgaagaacggcgaggacatccacctggtcctggacgcgccgcccgacccggccctggac
cgggtgcgggaggaggagtggccgctggtggacgacgggcccggcgccacgggctaccac
gaccagctgacggtggcgggcaagagccacgagcgggtgctcaccgtgtccctctgggac
tgcgaccggcgcttccgggtcaagatccggggcttcgacgggccggccgcgcccccgcgg
ggccccgagcccaccgtgttcgtggaggccaaggtccagcacgggcagcagctgctgagc
cagagcaggacgaccagcaagccctgggccgaggaggtgctgtggaatcagtggctcgag
ttcggcatccgcatcaaggatctgccccggggggccctgctcaacctgcagatctactgc
ggccgggcccagggcgggccgccccccgcgcccggctcccccgggcccggctccgacccc
cgggcccggcaccagctgctctactacgtcaacctgctgctggtggaccaccgctccctc
ctgcgccgcgggggctacgtcctgcacatgtggaagacctccgggaaggaggacggccgc
ggcagcctcaacgccgacaagctcacctcggccaccaaccccgacaaggagaactccgtg
gccatctcagtcctgctggacgactactgccacccagtcgccctgcccaagcaccggccc
gcctccggccccgacggggccggggccggggcggggggccgggccgagatgcccaaccag
ctccgcaagcagctggaggagatcgtcgccaccgaccccctccacccgctcagcgccgag
gacaaggagctgctctggcacttccggcacgagagcctgaagcaccccgaggcctacccc
aagctcttcagcgccgtcgactgggggcggcaggagaccgtggccgtggcctaccggctg
ctcgcccgccgggaggtctgggaccggagcgccctggacgtcggcttgaccctgcagctc
ctggactgcaacttctccgacgagaacgtgcgagccatggccgtgcagaagctggagagc
ctggaggacgacgacgtcctgcacttcctgctgcagctggtgcaggccgtgaagtttgaa
ccgtaccacgatagcgccctggcccgattcctgctgaagcgtggtctgaggaacaagagg
atcggccactttctgttctggttcttgaggagcgagatcgctcagtcgccgcactaccag
cagaggttcgcggtgctcctggaggcctacctccggggctgcggccaagccatgctccaa
gacttcaccaggcaggtccaggtcacccgcctgctgcacaagctcacgctcgaaatcaag
tcgctctccgccgacaagtacgacgtcaccccccaagtcgttgctcaacttaaggaaaag
cttgaaaacctgcagaactctcaccttccggacagcttcagagttccctacgatcctggc
ctgaaggccggaaagttggtgattgaaaaatgcaaagtgatggcctccaagaaaaagccc
ctctggctggagttccagtgcgccgaccccacggccctgtccagcgaaaccatcggggtc
atcttcaaacatggcgatgacctccggcaggacatgctcatccttcagatcctacgaatt
atggagtcgatctgggagacggagtctttggacttgtgtctgctgccttatggctgcatt
tccactggagataaaataggtaagccgcctctgggagccagtgagaactctctcagctaa
gcgataagtcagaaggacctgggttctgatcccggctctgccaattgcttgctgtgtgac
cttgggcgagtcacttcacttctctgtgcctcagtttcctcagctgtacagcgggtgttc
aatacctgttctctcaagctcacctccaccctctatacaggtgctnncaatcctgactct
tcccttctcctaggaaatctgttccatatcgactttgggcacattcttgggaattacaaa
agtttcctgggcatcagtaaagagagagtccccttcgtgctgacccccgacttcctgttt
gtgatggggacagctgggaagaagaccagcaagcacttccagaaatttcaggaagtttgt
gtccgagcttacctggccctccggcaccacaccaacctgctgatcatcctgttctccatg
atgctgatgacggggatgccccagctgaccagtaaggaggacatcgcctacatcagggac
gccctgaccgtggggaagagcgaagaggaggcggagaagtacttcctggaccagattgag
gtgtgccgagacaagggctggaccgtgcagtgtaactggtttctgcacctggtgctgggc
atcaaacaaggcgagaagcactctacatag

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