KEGG   Ornithorhynchus anatinus (platypus): 100078757Help
Entry
100078757         CDS       T01045                                 

Gene name
PLCG1
Definition
phospholipase C, gamma 1
Orthology
K01116  
phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
Inositol phosphate metabolism
Metabolic pathways
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
NF-kappa B signaling pathway
HIF-1 signaling pathway
Phosphatidylinositol signaling system
VEGF signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Inflammatory mediator regulation of TRP channels
Thyroid hormone signaling pathway
Epstein-Barr virus infection
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Glioma
Non-small cell lung cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:oaa00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100078757 (PLCG1)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100078757 (PLCG1)
   04015 Rap1 signaling pathway
    100078757 (PLCG1)
   04012 ErbB signaling pathway
    100078757 (PLCG1)
   04370 VEGF signaling pathway
    100078757 (PLCG1)
   04064 NF-kappa B signaling pathway
    100078757 (PLCG1)
   04066 HIF-1 signaling pathway
    100078757 (PLCG1)
   04020 Calcium signaling pathway
    100078757 (PLCG1)
   04070 Phosphatidylinositol signaling system
    100078757 (PLCG1)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    100078757 (PLCG1)
   04660 T cell receptor signaling pathway
    100078757 (PLCG1)
   04664 Fc epsilon RI signaling pathway
    100078757 (PLCG1)
   04666 Fc gamma R-mediated phagocytosis
    100078757 (PLCG1)
   04670 Leukocyte transendothelial migration
    100078757 (PLCG1)
  Endocrine system
   04919 Thyroid hormone signaling pathway
    100078757 (PLCG1)
  Nervous system
   04722 Neurotrophin signaling pathway
    100078757 (PLCG1)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100078757 (PLCG1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100078757 (PLCG1)
   05206 MicroRNAs in cancer
    100078757 (PLCG1)
   05205 Proteoglycans in cancer
    100078757 (PLCG1)
   05214 Glioma
    100078757 (PLCG1)
   05223 Non-small cell lung cancer
    100078757 (PLCG1)
  Infectious diseases
   05169 Epstein-Barr virus infection
    100078757 (PLCG1)
Enzymes [BR:oaa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100078757 (PLCG1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 623 aa AA seqDB search
MAAAAGAVGAFNGFAPCIQSEAQAAHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETR
QITWSRGSDKIEGGTACHLSCFIWCCTGVVASLNFSLLYRWYHASLTRTQAEHMLMRVPR
DGAFLVRKRSEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLY
RKMRLRYPINEETLEKIGTAGGRGGTEGILQEFSGGAQSDRDGLSPESWRLGMTQPGSPR
ASNCPGPGTLRVGVGERAGRLGVRLTAPPHASSPAAIRPEGKNSRLYVFSVSMASLSHWS
LDVAADTQEDLQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYCRPVPFDEE
TAAVWVGVAAAAPPLPTDKPMQMNQALFMSGGRCGYVMQPCSMRDDVFDPFDKNSLRGLE
SWTINIEVLGARHLPKNGRGIVCPFVEIEVSGADYDNAKQKTEFVVDNGLNPVWPPKPFQ
FQIINPEFAFLRFVVYEEDMFSDQNFLAQATFLVKGLKSGYRAVPLKNNYSEDLELASLL
IKINIHPAKENGELSQFSPASLRERGSDSGQLLNSRPRVGSFEARYQQPFEDFRLSPEQL
AEHFEVRERRALRRTRVNGDNRL
NT seq 1872 nt NT seq  +upstreamnt  +downstreamnt
atggcagcagcggcaggggctgtgggcgccttcaacggtttcgcgccctgcatccagtcc
gaggcccaggccgcccacctctgccggagcctggaggtgggcaccgtgatgactttgttt
tactcgaaaaaatctcagcggccggagaggaaaactttccaggtcaaactggaaaccagg
cagatcacatggagcagaggctcggataaaatcgaaggaggcaccgcctgccacctctcc
tgcttcatctggtgctgcaccggtgtggtggccagtttgaatttctctcttctgtatagg
tggtaccacgccagcctaacgcggacccaggcggagcacatgctcatgagggtcccgcgg
gatggggccttccttgtgcgcaagaggagcgagcccaactcctacgccatttccttccgg
gcggaagggaagatcaagcactgccgcgtccagcaggagggccagacggtcatgctgggc
aactcggagttcgacagcctcgtggacctcatcagctactacgagaagcacccgctgtac
cgcaagatgagactgcgttatcctatcaatgaggagacgctggagaagataggcaccgcg
ggggggaggggcggcacagagggaattttacaagagttttccgggggcgcacaaagtgac
cgggacgggctctctccggagagctggcggttggggatgacacagccgggctctccgaga
gccagcaactgccccgggcctgggaccctccgggtgggggtgggggaacgggctggaagg
ctcggcgtccggctgacggccccaccccacgcttcgtccccggcagccatccgcccggag
gggaagaacagccggctgtacgtattctccgtgagcatggcctcgttgtcgcactggtct
ctggacgtggcggccgacacgcaggaggacctgcaggactgggtgaagaagattcgcgag
gtggcccagaccgcagacgccaggctcacagaagggaagatgatggaacgaaggaagaag
atcgccttggagctgtccgagctggtcgtctactgccggccggtgcctttcgatgaagag
acagcagcggtgtgggtgggcgtggccgctgcagcccctcccctgcccacagacaagccc
atgcagatgaaccaggcgctgttcatgtccggcggccgctgtggctacgtgatgcagccc
tgcagcatgcgcgacgacgtcttcgaccccttcgacaagaacagcctccgcggtctcgag
tcgtggaccattaacatcgaggtcctgggggctcggcatctgcccaagaacggcaggggc
atcgtgtgcccatttgtggagatcgaggtgtctggggccgactatgacaacgccaagcag
aagaccgaatttgtggtggacaacggtctgaaccccgtatggccccccaagcccttccag
ttccagatcatcaaccctgagtttgccttcctgcgcttcgtcgtgtatgaagaggacatg
ttcagtgaccaaaacttcctggcccaggccacattcctggtgaaaggactgaaatcagga
tacagagcggtgcccctgaagaacaactacagcgaggacttggagttggcttctctcctc
attaagatcaacatccacccggccaaggagaacggcgagctgagccagttcagccccgcg
tccctgcgagagcggggtagcgactcgggccagctcctcaatagccgcccccgcgtgggc
tccttcgaagcccgctaccagcagccgttcgaggacttccgtctttccccggagcagcta
gccgagcacttcgaggtccgggagcgaagggccttgcggaggaccagagtcaacggagac
aatcgcctctag

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