KEGG   Ornithorhynchus anatinus (platypus): 100084432Help
Entry
100084432         CDS       T01045                                 

Gene name
PDGFRA
Definition
platelet-derived growth factor receptor, alpha polypeptide
Orthology
K04363  
platelet-derived growth factor receptor alpha [EC:2.7.10.1]
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
Cytokine-cytokine receptor interaction
Endocytosis
PI3K-Akt signaling pathway
Focal adhesion
Gap junction
Regulation of actin cytoskeleton
HTLV-I infection
Pathways in cancer
MicroRNAs in cancer
Glioma
Prostate cancer
Melanoma
Central carbon metabolism in cancer
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:oaa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100084432 (PDGFRA)
   04015 Rap1 signaling pathway
    100084432 (PDGFRA)
   04010 MAPK signaling pathway
    100084432 (PDGFRA)
   04020 Calcium signaling pathway
    100084432 (PDGFRA)
   04151 PI3K-Akt signaling pathway
    100084432 (PDGFRA)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100084432 (PDGFRA)
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    100084432 (PDGFRA)
  Cell motility
   04810 Regulation of actin cytoskeleton
    100084432 (PDGFRA)
  Cellular commiunity
   04510 Focal adhesion
    100084432 (PDGFRA)
   04540 Gap junction
    100084432 (PDGFRA)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100084432 (PDGFRA)
   05230 Central carbon metabolism in cancer
    100084432 (PDGFRA)
   05231 Choline metabolism in cancer
    100084432 (PDGFRA)
   05206 MicroRNAs in cancer
    100084432 (PDGFRA)
   05214 Glioma
    100084432 (PDGFRA)
   05218 Melanoma
    100084432 (PDGFRA)
   05215 Prostate cancer
    100084432 (PDGFRA)
  Infectious diseases
   05166 HTLV-I infection
    100084432 (PDGFRA)
Enzymes [BR:oaa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100084432 (PDGFRA)
Protein kinases [BR:oaa01001]
 Tyrosine protein kinases
  PDGFR family [OT]
   100084432 (PDGFRA)
Enzyme-linked receptors [BR:oaa01020]
 Receptor tyrosine kinases
  RTK class III (PDGF receptor family)
   100084432 (PDGFRA)
Cytokine receptors [BR:oaa04050]
 Receptor tyrosine kinase
  RTK class III (PDGF receptor family)
   100084432 (PDGFRA)
Cellular antigens [BR:oaa04090]
 Proteins
  100084432 (PDGFRA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 856 aa AA seqDB search
MGPSPWTCLILGYLLSGLRRGACQPPFPTIVPDEEELVVSLHMSFSLRCTGDSEVSWQFP
TLDDGSPGVSVRSEENNSGSFVAVLEVANASAVHTGLYTCYYNHTQTQEAEAEGRDVYVY
VPDPDVAFVPSVMVDHFIVVEEDDSTVIPCRSTDPQARVTLHASDGKEVSAFYDSRQGFL
GHFDMGSYTCETTIRGRKFQTLEFNVYTLRATPEIVVEMEAPKTVYKTGETIVVTCAVLD
NEVVDFQWNYPGKVRDKGIIKLDEIKVPSIKLVYTLTVPEATAKDGGDYECAARHATKEA
KQIKKVTITVHERGFVRLQPGFGPVEAVNLHEVRHFGVELEAYPPPRVSWLKNDVSLTEN
LTEITTSLEKIQEIRYQSKLKLIRAKEEDSGHYTIVVQNEDDIMNYTFELLVQVPASILD
LVDDHHGSAGGQTVRCVAEGTPLPDVDWMVCRDIKKCNNETSWTLLTANASDIAVEAHVG
DRDTMESQVTFQQVEETLAVRCLAKNHLGAVTRELKLVAPALRSELTVAAAVLVLLVIVI
VSLIVLVIIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRIL
GSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVN
LLGACTKSGPIYIITEYCFYGDLVNYLHKNRDNFLTRHPEKTKKELDIFGMSPADESTRS
YVILSFENNGDYMDMKQADATQYVSMLERKESSKYSDIQRSLYNRPASYKKKSVSDSEVT
DLLSDDGSEGLGLLDLLSFTYQVSRGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGL
ARDIMHDSNYVSKGSV
NT seq 2569 nt NT seq  +upstreamnt  +downstreamnt
atgggtccttccccatggacatgcctgatcttggggtatctgctgtcagggctacgacgc
ggggcctgccagcccccgtttcccaccatcgtgccggacgaggaggagctggtggtgtcc
ctgcacatgtccttctccctgcggtgcaccggggacagcgaggtcagctggcagttcccc
acgctggacgacgggagccccggcgtgtccgtccgcagtgaggagaacaacagcggctcc
ttcgtggccgtgctggaggtggccaacgcctcggccgtgcacaccggcctctacacctgc
tattacaaccacacgcagacccaggaggccgaggccgaaggccgggatgtctacgtctac
gtgcctgaccccgacgtcgccttcgtgccctcggtcatggtcgaccacttcatcgtcgtg
gaggaagacgattccaccgtgatcccctgtcgctccaccgacccgcaggcgcgggtgacc
ctgcacgccagcgacggcaaggaggtctctgccttctacgacagccgccaaggtttcctg
ggtcacttcgacatggggtcctacacgtgcgagacgaccatccgcggcaggaagttccag
accctcgagttcaacgtctacaccttgcgagccaccccggagatcgtcgtggagatggag
gccccgaagacggtgtacaagacgggcgagaccatcgtggtcacctgcgccgtcctggac
aacgaggtggtcgatttccagtggaactacccggggaaggtgagggacaagggcatcatc
aagctggacgagattaaggtcccgtccatcaagctggtgtacaccctgacggtgcccgag
gccacggccaaggacggcggcgattacgagtgtgctgcccgccacgccaccaaggaggcg
aagcagataaagaaggtcaccatcaccgtccacgagagaggcttcgtccggctccagccc
ggcttcggccccgtggaggccgtgaacctgcacgaggtccggcattttggcgtggagctg
gaggcctaccccccgcccagggtgtcctggctgaagaacgacgtgtcgctcaccgagaac
ctgaccgagatcaccaccagcctggagaagatccaggagatcaggtatcagagcaagctg
aagctaatccgagcaaaggaggaagacagtgggcactacacaatcgtggtgcaaaacgag
gatgatattatgaactacacctttgagctgctggttcaagtgccggcctccatcttggat
ctggtggacgaccaccatggctcggcggggggccagaccgtccgctgtgtcgccgaaggg
acgccgctgcccgacgtcgactggatggtttgcagggacattaaaaaatgcaacaacgag
acctcgtggaccctcctcaccgccaacgcgtccgacatcgccgtggaggcccacgtgggt
gacagggacacgatggagagtcaggtgaccttccagcaggtggaggagacgctggcggtg
cgctgcttggccaagaaccaccttggggccgtgacgcgggagctgaagctggtggcccct
gccctgcgctctgagttgaccgtggctgctgccgtcctggtgctcctggtgatcgtcatc
gtctccctcatcgtgctggtcatcatctggaaacagaagccgcgctatgagatccgatgg
cgggtcatcgagtccatcagcccggacggccacgagtatatctacgtggacccgatgcag
ctcccctacgactcgcgctgggagtttccgagggacgggctggtgctgggccgaatcctt
gggtccggagcatttgggaaggtggtggaaggcactgcatacgggctgagccgctcccag
cccgtgatgaaggtggccgtgaaaatgttaaaacccacggctcgatccagcgagaagcag
gccctcatgtcggagctgaagatcatgacgcatctgggcccccatctgaacatcgtgaac
ctcctgggggcctgcaccaaatcaggacccatctacatcatcaccgagtactgcttctac
ggcgacctggtcaactacctgcacaagaaccgcgataacttcctgactcgccacccggag
aagacgaagaaagagctggacatcttcggcatgagccctgccgacgagagcaccaggagc
tacgtcatcctctcatttgaaaacaacggggactacatggacatgaagcaggcggacgcc
acacagtacgtgtccatgttggagaggaaggagtcgtccaagtactcggacatccagcga
tccctgtacaaccggccggcctcctacaagaagaagtccgtgtcggactctgaagtcacg
gacctcctgtcggacgatggttcggaaggccttggcctgctggacctgctgagctttacc
taccaggtgtctcgcgggatggagttcctagcttcgaaaaactgcgtccaccgggatctg
gctgcgcggaacgtcctgctggcccaagggaagatcgtgaagatctgcgacttcgggctg
gcgagggacatcatgcacgactccaactacgtgtccaagggcagcgtac

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